{"id":"https://openalex.org/W970440434","doi":null,"title":"S1P Receptor-Mediated Effects in Human Schlemm\u2019s Canal Endothelial Cells","display_name":"S1P Receptor-Mediated Effects in Human Schlemm\u2019s Canal Endothelial Cells","publication_year":2008,"publication_date":"2008-05-14","ids":{"openalex":"https://openalex.org/W970440434","mag":"970440434"},"language":"en","primary_location":{"id":"mag:970440434","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2376376","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055833053","display_name":"Grant M. Sumida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grant M. Sumida","raw_affiliation_strings":["Ophthalmology and Vision Science, University of Arizona, Tucson, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology and Vision Science, University of Arizona, Tucson, Arizona","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052639747","display_name":"W. D. Stamer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. D. Stamer","raw_affiliation_strings":["Ophthalmology and Vision Science, University of Arizona, Tucson, Arizona"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology and Vision Science, University of Arizona, Tucson, Arizona","institution_ids":["https://openalex.org/I138006243"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I138006243"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05428904,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"49","issue":"13","first_page":"682","last_page":"682"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.7128999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.7128999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.19930000603199005,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sphingosine-1-phosphate","display_name":"sphingosine-1-phosphate","score":0.9359999895095825},{"id":"https://openalex.org/keywords/s1p-receptors","display_name":"S1P receptors","score":0.9399999976158142},{"id":"https://openalex.org/keywords/schlemm-s-canal-endothelial-cells","display_name":"Schlemm's canal endothelial cells","score":0.9739999771118164},{"id":"https://openalex.org/keywords/aqueous-humor-outflow","display_name":"aqueous humor outflow","score":0.9259999990463257},{"id":"https://openalex.org/keywords/uveoscleral-outflow","display_name":"uveoscleral outflow","score":0.8349999785423279},{"id":"https://openalex.org/keywords/aqueous-humor","display_name":"aqueous humor","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C2780186721","wikidata":"https://www.wikidata.org/wiki/Q1535320","display_name":"Schlemm's canal","level":4,"score":0.9836263060569763},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.45716726779937744},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.41250914335250854},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.36748218536376953},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22783353924751282},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22278419137001038},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.21145689487457275},{"id":"https://openalex.org/C2781121420","wikidata":"https://www.wikidata.org/wiki/Q750873","display_name":"Trabecular meshwork","level":3,"score":0.11280626058578491},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.08801081776618958},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:970440434","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2376376","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1201247432","https://openalex.org/W946213606","https://openalex.org/W959100840","https://openalex.org/W2576094115","https://openalex.org/W1014345279","https://openalex.org/W2915474521","https://openalex.org/W1217966882","https://openalex.org/W7062278877","https://openalex.org/W3213970422","https://openalex.org/W3182298362"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}