{"id":"https://openalex.org/W97001444","doi":null,"title":"Influence of malnutrition on regeneration and composition of the liver in rats.","display_name":"Influence of malnutrition on regeneration and composition of the liver in rats.","publication_year":1990,"publication_date":"1990-10-01","ids":{"openalex":"https://openalex.org/W97001444","mag":"97001444","pmid":"https://pubmed.ncbi.nlm.nih.gov/2264430"},"language":"en","primary_location":{"id":"pmid:2264430","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2264430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta chirurgica Scandinavica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022692463","display_name":"S. Skullman","orcid":"https://orcid.org/0000-0002-7649-9085","observed_orcids":["https://orcid.org/0000-0002-7649-9085"]},"institutions":[{"id":"https://openalex.org/I4210151885","display_name":"Link\u00f6ping University Hospital","ror":"https://ror.org/05h1aye87","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210151885"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"S Skullman","raw_affiliation_strings":["Department of Surgery, University Hospital, Link\u00f6ping, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, University Hospital, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I4210151885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037166555","display_name":"Ingemar Ihse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Ihse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111284449","display_name":"J Larsson","orcid":"https://orcid.org/0000-0003-2877-5943","observed_orcids":["https://orcid.org/0000-0003-2877-5943"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Larsson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8211,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.77389474,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"156","issue":"10","first_page":"717","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.9610000252723694},{"id":"https://openalex.org/keywords/liver-regeneration","display_name":"liver regeneration","score":0.9599999785423279},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.9769999980926514},{"id":"https://openalex.org/keywords/liver-composition","display_name":"liver composition","score":0.7960000038146973},{"id":"https://openalex.org/keywords/glycogen","display_name":"glycogen","score":0.675000011920929},{"id":"https://openalex.org/keywords/steatosis","display_name":"steatosis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/rna-content","display_name":"RNA content","score":0.6899999976158142},{"id":"https://openalex.org/keywords/liver-protein-content","display_name":"liver protein content","score":0.5730000138282776},{"id":"https://openalex.org/keywords/liver-water-content","display_name":"liver water content","score":0.6259999871253967},{"id":"https://openalex.org/keywords/cell-replication","display_name":"cell replication","score":0.4560000002384186},{"id":"https://openalex.org/keywords/postoperative-mortality","display_name":"postoperative mortality","score":0.7950000166893005},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C2776795407","wikidata":"https://www.wikidata.org/wiki/Q19597761","display_name":"Liver regeneration","level":3,"score":0.8280600309371948},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.7870067358016968},{"id":"https://openalex.org/C551997983","wikidata":"https://www.wikidata.org/wiki/Q12167","display_name":"Malnutrition","level":2,"score":0.7207075953483582},{"id":"https://openalex.org/C2776909242","wikidata":"https://www.wikidata.org/wiki/Q1514021","display_name":"Hepatectomy","level":3,"score":0.6675699949264526},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6240176558494568},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5967726111412048},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5681685209274292},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5285685658454895},{"id":"https://openalex.org/C2779613291","wikidata":"https://www.wikidata.org/wiki/Q4082071","display_name":"Protein\u2013energy malnutrition","level":3,"score":0.5272150039672852},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.25137823820114136},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22504934668540955},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006498","descriptor_name":"Hepatectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008112","descriptor_name":"Liver Glycogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008115","descriptor_name":"Liver Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009748","descriptor_name":"Nutrition Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009748","descriptor_name":"Nutrition Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009748","descriptor_name":"Nutrition Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2264430","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2264430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta chirurgica Scandinavica","raw_type":"Journal Article"},{"id":"mag:97001444","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2264430","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899},{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.5666999816894531}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2068622496","https://openalex.org/W2096498923","https://openalex.org/W2003763300","https://openalex.org/W2095039878","https://openalex.org/W2054847441","https://openalex.org/W2054449307","https://openalex.org/W342747258","https://openalex.org/W2337231093","https://openalex.org/W2235295462","https://openalex.org/W1970948919"],"abstract_inverted_index":{"Using":[0],"a":[1,133,138,149,164,174,179],"new":[2],"experimental":[3],"model":[4],"of":[5,10,33,83,95,103,115,125,141,160,202],"protein-calorie":[6],"starvation,":[7],"the":[8,16,81,88,193,200],"impact":[9],"malnutrition":[11,22,147,192],"on":[12],"liver":[13,19,116,168,208],"regeneration,":[14,24,189],"and":[15,23,61,86,109,137,154,178],"changes":[17],"in":[18,151,167,176,181],"composition":[20,169],"during":[21,146,188,191],"were":[25,29,41,54,67,78,90,99],"studied.":[26],"Forty-one":[27],"rats":[28,44,56,70,89],"allocated":[30],"to":[31],"one":[32],"3":[34],"groups:":[35],"group":[36,49,62],"I":[37],"(n":[38,51,64],"=":[39,52,65],"13)":[40],"normally":[42,68],"nourished":[43,69],"which":[45,57,71],"underwent":[46,58,72],"partial":[47,59,84],"hepatectomy,":[48,60],"II":[50],"16)":[53],"semistarved":[55],"III":[63],"12)":[66],"sham":[73],"operations.":[74],"Liver":[75],"biopsy":[76],"specimens":[77],"taken":[79],"at":[80],"time":[82],"hepatectomy":[85],"when":[87],"killed":[91],"after":[92,122],"48":[93,158],"hours":[94,159],"regeneration.":[96,142,209],"The":[97,112,143,197],"samples":[98],"used":[100],"for":[101,207],"determination":[102],"water,":[104],"fat,":[105],"glycogen,":[106],"protein,":[107],"DNA,":[108],"RNA":[110,184],"content.":[111,183],"replication":[113],"rate":[114,140],"cells":[117],"was":[118,130,163,186],"measured":[119],"by":[120],"autoradiography":[121],"continuous":[123],"incorporation":[124],"tritium":[126],"labelled":[127],"thymidine.":[128],"Malnutrition":[129],"associated":[131],"with":[132,148,170],"higher":[134],"postoperative":[135],"mortality":[136],"reduced":[139],"livers":[144],"changed":[145],"reduction":[150],"both":[152],"size":[153],"glycogen":[155,177],"concentration.":[156],"After":[157],"regeneration":[161],"there":[162],"marked":[165],"change":[166],"severe":[171],"fatty":[172],"degeneration,":[173],"fall":[175],"rise":[180],"water":[182],"concentration":[185],"stimulated":[187],"but":[190],"protein":[194],"content":[195],"decreased.":[196],"results":[198],"emphasise":[199],"importance":[201],"an":[203],"adequate":[204],"nutritional":[205],"state":[206]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}