{"id":"https://openalex.org/W9696029","doi":"https://doi.org/10.1007/0-306-46875-1_45","title":"The Use of Peptones as Medium Additives for High-Density Perfusion Cultures of Animal Cells","display_name":"The Use of Peptones as Medium Additives for High-Density Perfusion Cultures of Animal Cells","publication_year":2008,"publication_date":"2008-08-14","ids":{"openalex":"https://openalex.org/W9696029","doi":"https://doi.org/10.1007/0-306-46875-1_45","mag":"9696029"},"language":"en","primary_location":{"id":"doi:10.1007/0-306-46875-1_45","doi":"https://doi.org/10.1007/0-306-46875-1_45","is_oa":false,"landing_page_url":"https://doi.org/10.1007/0-306-46875-1_45","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Cell Technology: Products from Cells, Cells as Products","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2477113365","display_name":"Animal Cell Technology: Products from Cells, Cells as Products"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042450378","display_name":"R\u00fcdiger Heidemann","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Heidemann","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041451807","display_name":"Chuqi Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Zhang","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102335873","display_name":"Haijun Qi","orcid":"https://orcid.org/0009-0005-8436-4526","observed_orcids":["https://orcid.org/0009-0005-8436-4526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Qi","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053177941","display_name":"James Larrick Rule","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Rule","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072979132","display_name":"Carl Rozales","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Rozales","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003485809","display_name":"S. Park","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Park","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063893560","display_name":"Sandra L. Chuppa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Chuppa","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111634012","display_name":"Manas K. Ray","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Ray","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113469126","display_name":"James D. Michaels","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Michaels","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017208832","display_name":"Konstantin Konstantinov","orcid":"https://orcid.org/0000-0003-4919-6385","observed_orcids":["https://orcid.org/0000-0003-4919-6385"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Konstantinov","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089584128","display_name":"David Naveh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Naveh","raw_affiliation_strings":["Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","Bayer Corporation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Corporation, 800 Dwight Way, Berkeley, CA, 94710, USA","institution_ids":[]},{"raw_affiliation_string":"Bayer Corporation;","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00525701,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"195","last_page":"197"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10864","display_name":"Fluid Dynamics and Mixing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peptone","display_name":"peptone","score":0.9649999737739563},{"id":"https://openalex.org/keywords/perfusion-culture","display_name":"perfusion culture","score":0.7630000114440918},{"id":"https://openalex.org/keywords/high-cell-density-culture","display_name":"high cell density culture","score":0.6990000009536743},{"id":"https://openalex.org/keywords/animal-cell-culture","display_name":"animal cell culture","score":0.5180000066757202},{"id":"https://openalex.org/keywords/bhk-cells","display_name":"BHK cells","score":0.824999988079071},{"id":"https://openalex.org/keywords/specific-productivity","display_name":"specific productivity","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C28800991","wikidata":"https://www.wikidata.org/wiki/Q15634405","display_name":"Hydrolysate","level":3,"score":0.6929616332054138},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.6730462312698364},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5692882537841797},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5621800422668457},{"id":"https://openalex.org/C168170006","wikidata":"https://www.wikidata.org/wiki/Q864699","display_name":"Bioreactor","level":2,"score":0.43960756063461304},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3640565872192383},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34491369128227234},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.33754104375839233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25225794315338135},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.21427512168884277},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/0-306-46875-1_45","doi":"https://doi.org/10.1007/0-306-46875-1_45","is_oa":false,"landing_page_url":"https://doi.org/10.1007/0-306-46875-1_45","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Animal Cell Technology: Products from Cells, Cells as Products","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4359000027179718,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"sustainable_development_goals_aurora":[{"score":0.8100000023841858,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1976724356","https://openalex.org/W1983866106","https://openalex.org/W1994929719","https://openalex.org/W2058726380","https://openalex.org/W2072290511","https://openalex.org/W2081519519","https://openalex.org/W2091300510","https://openalex.org/W2139433719"],"related_works":["https://openalex.org/W2103598808","https://openalex.org/W4248839768","https://openalex.org/W2358052181","https://openalex.org/W2327117200","https://openalex.org/W2052058434","https://openalex.org/W3043133313","https://openalex.org/W2576188444","https://openalex.org/W2127656351","https://openalex.org/W2377972770","https://openalex.org/W2366452656"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2025-10-10T00:00:00"}