{"id":"https://openalex.org/W96838056","doi":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","title":"THE USE OF SPECIFIC ANTISERA TO STUDY THE DEVELOPMENTAL REGULATION OF GUANINE NUCLEOTIDE BINDING PROTEINS","display_name":"THE USE OF SPECIFIC ANTISERA TO STUDY THE DEVELOPMENTAL REGULATION OF GUANINE NUCLEOTIDE BINDING PROTEINS","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W96838056","doi":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","mag":"96838056"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-08-035588-7.50095-9","doi":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protides of the Biological Fluids","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4206466887","display_name":"Protides of the Biological Fluids"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051585961","display_name":"Graeme Milligan","orcid":"https://orcid.org/0000-0002-6946-3519","observed_orcids":["https://orcid.org/0000-0002-6946-3519"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"GRAEME MILLIGAN","raw_affiliation_strings":["Molecular Pharmacology Group, Departments of Biochemistry and Pharmacology, University of Glasgow, Glasgow G12 8QQ, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Pharmacology Group, Departments of Biochemistry and Pharmacology, University of Glasgow, Glasgow G12 8QQ, Scotland","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058305327","display_name":"Peter Gierschik","orcid":"https://orcid.org/0000-0001-9295-5231","observed_orcids":["https://orcid.org/0000-0001-9295-5231"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"PETER GIERSCHIK","raw_affiliation_strings":["Department of Pharmacology, University of Heidelberg, D-6900, Heidelberg, F.R.G"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Heidelberg, D-6900, Heidelberg, F.R.G","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018415215","display_name":"Cecilia G. Unson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"CECILIA G. UNSON","raw_affiliation_strings":["Department of Biochemistry, The Rockefeller University, New York, NY 10021, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, The Rockefeller University, New York, NY 10021, U.S.A","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111658095","display_name":"Allen M. Spiegel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ALLEN M. SPIEGEL","raw_affiliation_strings":["Metabolic Diseases Branch, National Institute of Diabetes, Digestive and Kidney Disease, N.I.H., Bethesda, MD 20892, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Metabolic Diseases Branch, National Institute of Diabetes, Digestive and Kidney Disease, N.I.H., Bethesda, MD 20892, U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3907,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54987147,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"415","last_page":"418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.08009999990463257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/g-proteins","display_name":"G proteins","score":0.9480000138282776},{"id":"https://openalex.org/keywords/alpha-subunit","display_name":"alpha subunit","score":0.7990000247955322},{"id":"https://openalex.org/keywords/antisera","display_name":"antisera","score":0.9139999747276306},{"id":"https://openalex.org/keywords/peptide-specific-antibodies","display_name":"peptide-specific antibodies","score":0.531000018119812},{"id":"https://openalex.org/keywords/developmental-regulation","display_name":"developmental regulation","score":0.925000011920929},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.6909999847412109},{"id":"https://openalex.org/keywords/developmental-biology","display_name":"developmental biology","score":0.3409999907016754}],"concepts":[{"id":"https://openalex.org/C2778301229","wikidata":"https://www.wikidata.org/wiki/Q169313","display_name":"Guanine","level":4,"score":0.8177745342254639},{"id":"https://openalex.org/C91523082","wikidata":"https://www.wikidata.org/wiki/Q420496","display_name":"Antiserum","level":3,"score":0.740473747253418},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.6464928984642029},{"id":"https://openalex.org/C94966510","wikidata":"https://www.wikidata.org/wiki/Q2252764","display_name":"DNA-binding protein","level":4,"score":0.5057938098907471},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5041497945785522},{"id":"https://openalex.org/C84148353","wikidata":"https://www.wikidata.org/wiki/Q863908","display_name":"Nucleic acid sequence","level":3,"score":0.4331549406051636},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4286803901195526},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.334725558757782},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31951919198036194},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.19322139024734497},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16298213601112366},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.10478004813194275}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-08-035588-7.50095-9","doi":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-035588-7.50095-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protides of the Biological Fluids","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1483853294","https://openalex.org/W1511887721","https://openalex.org/W1533101741","https://openalex.org/W1539001739","https://openalex.org/W1969814518","https://openalex.org/W1982177082","https://openalex.org/W1982840305","https://openalex.org/W1984430234","https://openalex.org/W2023023900","https://openalex.org/W2037804679","https://openalex.org/W2038993552","https://openalex.org/W2117750174","https://openalex.org/W2345675544"],"related_works":["https://openalex.org/W2032941398","https://openalex.org/W1969627143","https://openalex.org/W2510791818","https://openalex.org/W1686767996","https://openalex.org/W2345675544","https://openalex.org/W1619407925","https://openalex.org/W2038993552","https://openalex.org/W1530899180","https://openalex.org/W1543712339","https://openalex.org/W1972394592"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}