{"id":"https://openalex.org/W965010486","doi":null,"title":"Over-Expression of (pro)renin Receptor in Mouse Retina Induces a Breakdown of Blood-Retinal-Barrier","display_name":"Over-Expression of (pro)renin Receptor in Mouse Retina Induces a Breakdown of Blood-Retinal-Barrier","publication_year":2010,"publication_date":"2010-04-17","ids":{"openalex":"https://openalex.org/W965010486","mag":"965010486"},"language":"en","primary_location":{"id":"mag:965010486","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2373105","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064648564","display_name":"Bo Lei","orcid":"https://orcid.org/0000-0002-5497-0905","observed_orcids":["https://orcid.org/0000-0002-5497-0905"]},"institutions":[{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bo Lei","raw_affiliation_strings":["Ophthalmology, The First Affiliated Hospital, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing Medical University, Chongqing, China"],"raw_orcid":"https://orcid.org/0000-0002-5497-0905","affiliations":[{"raw_affiliation_string":"Ophthalmology, The First Affiliated Hospital, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Amit Verma","orcid":"https://orcid.org/0000-0003-3851-2987","observed_orcids":["https://orcid.org/0000-0003-3851-2987"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit Verma","raw_affiliation_strings":["University of Florida, Gainesville, Florida"],"raw_orcid":"https://orcid.org/0000-0003-3851-2987","affiliations":[{"raw_affiliation_string":"University of Florida, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082321377","display_name":"Zhiying Jenny Shan","orcid":"https://orcid.org/0000-0002-9763-205X","observed_orcids":["https://orcid.org/0000-0002-9763-205X"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhiying Shan","raw_affiliation_strings":["University of Florida, Gainesville, Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Florida, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086264524","display_name":"William W. Hauswirth","orcid":"https://orcid.org/0000-0002-3244-4947","observed_orcids":["https://orcid.org/0000-0002-3244-4947"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William W. Hauswirth","raw_affiliation_strings":["University of Florida, Gainesville, Florida"],"raw_orcid":"https://orcid.org/0000-0002-3244-4947","affiliations":[{"raw_affiliation_string":"University of Florida, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071839746","display_name":"Mohan K. Raizada","orcid":"https://orcid.org/0000-0002-1654-9597","observed_orcids":["https://orcid.org/0000-0002-1654-9597"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohan K. Raizada","raw_affiliation_strings":["University of Florida, Gainesville, Florida"],"raw_orcid":"https://orcid.org/0000-0002-1654-9597","affiliations":[{"raw_affiliation_string":"University of Florida, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102781871","display_name":"Hui Peng","orcid":"https://orcid.org/0000-0003-4758-3752","observed_orcids":["https://orcid.org/0000-0003-4758-3752"]},"institutions":[{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Peng","raw_affiliation_strings":["Ophthalmology, The First Affiliated Hospital, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing Medical University, Chongqing, China"],"raw_orcid":"https://orcid.org/0000-0003-4758-3752","affiliations":[{"raw_affiliation_string":"Ophthalmology, The First Affiliated Hospital, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing Medical University, Chongqing, China","institution_ids":["https://openalex.org/I87780372"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100350156","display_name":"Qi Li","orcid":"https://orcid.org/0000-0001-8015-2298","observed_orcids":["https://orcid.org/0000-0001-8015-2298"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qi Li","raw_affiliation_strings":["University of Florida, Gainesville, Florida"],"raw_orcid":"https://orcid.org/0000-0001-8015-2298","affiliations":[{"raw_affiliation_string":"University of Florida, Gainesville, Florida","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.05742777,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"51","issue":"13","first_page":"4490","last_page":"4490"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.6190999746322632,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.6190999746322632,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.30219998955726624,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.02160000056028366,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prorenin-receptor","display_name":"prorenin receptor","score":0.9359999895095825},{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.9229999780654907},{"id":"https://openalex.org/keywords/blood-retinal-barrier","display_name":"blood-retinal barrier","score":0.8679999709129333},{"id":"https://openalex.org/keywords/retinal-endothelium","display_name":"retinal endothelium","score":0.6809999942779541},{"id":"https://openalex.org/keywords/retinal-permeability","display_name":"retinal permeability","score":0.5410000085830688},{"id":"https://openalex.org/keywords/mouse-retina","display_name":"mouse retina","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.7564636468887329},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6178842186927795},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5201380848884583},{"id":"https://openalex.org/C2778371105","wikidata":"https://www.wikidata.org/wiki/Q1622103","display_name":"Blood\u2013retinal barrier","level":4,"score":0.5033037066459656},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5003869533538818},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3754262328147888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3264343738555908},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29447484016418457},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.28668928146362305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2808445692062378},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.21824488043785095},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2066907286643982},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.0},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:965010486","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2373105","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W849484861","https://openalex.org/W987929406","https://openalex.org/W835292938","https://openalex.org/W893039945","https://openalex.org/W2994316381","https://openalex.org/W1239063465","https://openalex.org/W3120035683","https://openalex.org/W782998229","https://openalex.org/W1182615664","https://openalex.org/W979146856"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}