{"id":"https://openalex.org/W96411552","doi":null,"title":"Effect of Ascorbate on Coagulation and Fibrinolytic Factors in the Septic Microvasculature","display_name":"Effect of Ascorbate on Coagulation and Fibrinolytic Factors in the Septic Microvasculature","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W96411552","mag":"96411552"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.685.6142","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.685.6142","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ir.lib.uwo.ca/cgi/viewcontent.cgi?article%3D3401%26context%3Detd","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044188481","display_name":"Scott B. Swarbreck","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Scott Swarbreck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5044188481"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00596539,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12554","display_name":"Vitamin C and Antioxidants Research","score":0.17180000245571136,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9559999704360962},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9549999833106995},{"id":"https://openalex.org/keywords/microcirculation","display_name":"microcirculation","score":0.6890000104904175},{"id":"https://openalex.org/keywords/microvascular-thrombosis","display_name":"microvascular thrombosis","score":0.824999988079071},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.925000011920929},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.9509999752044678},{"id":"https://openalex.org/keywords/platelets","display_name":"platelets","score":0.6600000262260437},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.9309999942779541},{"id":"https://openalex.org/keywords/streptokinase","display_name":"streptokinase","score":0.8410000205039978},{"id":"https://openalex.org/keywords/urokinase-type-plasminogen-activator","display_name":"urokinase","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tissue-plasminogen-activator","display_name":"tissue plasminogen activator","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7829999923706055},{"id":"https://openalex.org/keywords/ph-dependent-inhibition","display_name":"pH-dependent inhibition","score":0.4779999852180481},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.7703016996383667},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7590693235397339},{"id":"https://openalex.org/C2779679481","wikidata":"https://www.wikidata.org/wiki/Q13581432","display_name":"Plasminogen activator","level":2,"score":0.6268982887268066},{"id":"https://openalex.org/C2778734968","wikidata":"https://www.wikidata.org/wiki/Q823027","display_name":"Disseminated intravascular coagulation","level":2,"score":0.6143592000007629},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.6087260246276855},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5609127879142761},{"id":"https://openalex.org/C2776892390","wikidata":"https://www.wikidata.org/wiki/Q7119591","display_name":"Urokinase","level":2,"score":0.5308015942573547},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.5229183435440063},{"id":"https://openalex.org/C2776572282","wikidata":"https://www.wikidata.org/wiki/Q416351","display_name":"Tissue plasminogen activator","level":2,"score":0.4551917612552643},{"id":"https://openalex.org/C2780675426","wikidata":"https://www.wikidata.org/wiki/Q410485","display_name":"Plasminogen activator inhibitor-1","level":3,"score":0.4473414719104767},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.42807114124298096},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42372649908065796},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4207213819026947},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.41256183385849},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3493235409259796},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34334561228752136},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28037193417549133},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2676580548286438}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.685.6142","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.685.6142","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ir.lib.uwo.ca/cgi/viewcontent.cgi?article%3D3401%26context%3Detd","raw_type":"text"},{"id":"pmh:oai:ir.lib.uwo.ca:etd-3401","doi":null,"is_oa":false,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=3401&context=etd","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Thesis and Dissertation Repository","raw_type":"text"},{"id":"pmh:oai:uwo.scholaris.ca:20.500.14721/34823","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/20.500.14721/34823","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:96411552","doi":null,"is_oa":false,"landing_page_url":"https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=3401&context=etd","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":278,"referenced_works":["https://openalex.org/W99807885","https://openalex.org/W149664788","https://openalex.org/W247940974","https://openalex.org/W1135531092","https://openalex.org/W1235031025","https://openalex.org/W1498243413","https://openalex.org/W1507533499","https://openalex.org/W1520292841","https://openalex.org/W1551751498","https://openalex.org/W1566543831","https://openalex.org/W1578542647","https://openalex.org/W1596993093","https://openalex.org/W1650652405","https://openalex.org/W1670199153","https://openalex.org/W1706591859","https://openalex.org/W1753683453","https://openalex.org/W1754134899","https://openalex.org/W1832271492","https://openalex.org/W1837983320","https://openalex.org/W1845174424","https://openalex.org/W1849785625","https://openalex.org/W1858645903","https://openalex.org/W1880934458","https://openalex.org/W1892225420","https://openalex.org/W1896508015","https://openalex.org/W1930915741","https://openalex.org/W1940869776","https://openalex.org/W1943527316","https://openalex.org/W1963607779","https://openalex.org/W1963633267","https://openalex.org/W1963923094","https://openalex.org/W1965833894","https://openalex.org/W1966778344","https://openalex.org/W1968001274","https://openalex.org/W1968370071","https://openalex.org/W1969437137","https://openalex.org/W1969719203","https://openalex.org/W1972473400","https://openalex.org/W1973138645","https://openalex.org/W1973342199","https://openalex.org/W1973417048","https://openalex.org/W1973758538","https://openalex.org/W1975152371","https://openalex.org/W1975365056","https://openalex.org/W1976133531","https://openalex.org/W1977805115","https://openalex.org/W1978145860","https://openalex.org/W1979116900","https://openalex.org/W1979684801","https://openalex.org/W1979877104","https://openalex.org/W1980425507","https://openalex.org/W1980471018","https://openalex.org/W1981022170","https://openalex.org/W1982169353","https://openalex.org/W1982404108","https://openalex.org/W1982474751","https://openalex.org/W1983019829","https://openalex.org/W1983102624","https://openalex.org/W1983459827","https://openalex.org/W1983705436","https://openalex.org/W1983971452","https://openalex.org/W1984358837","https://openalex.org/W1984372443","https://openalex.org/W1984378104","https://openalex.org/W1985995339","https://openalex.org/W1986612880","https://openalex.org/W1986892842","https://openalex.org/W1987036848","https://openalex.org/W1987562115","https://openalex.org/W1988292100","https://openalex.org/W1988874765","https://openalex.org/W1988914477","https://openalex.org/W1989528047","https://openalex.org/W1990035048","https://openalex.org/W1992075095","https://openalex.org/W1992416484","https://openalex.org/W1993401250","https://openalex.org/W1993899027","https://openalex.org/W1994253596","https://openalex.org/W1995517654","https://openalex.org/W1996351596","https://openalex.org/W1997707248","https://openalex.org/W1998075600","https://openalex.org/W2000025994","https://openalex.org/W2001058555","https://openalex.org/W2003298222","https://openalex.org/W2003916882","https://openalex.org/W2005358532","https://openalex.org/W2005705211","https://openalex.org/W2006016016","https://openalex.org/W2006847107","https://openalex.org/W2007032123","https://openalex.org/W2012557847","https://openalex.org/W2012840031","https://openalex.org/W2015877067","https://openalex.org/W2016005395","https://openalex.org/W2016760535","https://openalex.org/W2017700181","https://openalex.org/W2017789103","https://openalex.org/W2019734149","https://openalex.org/W2024833873","https://openalex.org/W2024929151","https://openalex.org/W2025458140","https://openalex.org/W2026384914","https://openalex.org/W2028362773","https://openalex.org/W2029018980","https://openalex.org/W2029101566","https://openalex.org/W2029533353","https://openalex.org/W2029751479","https://openalex.org/W2031276022","https://openalex.org/W2031359454","https://openalex.org/W2031792227","https://openalex.org/W2031796113","https://openalex.org/W2032430567","https://openalex.org/W2033145724","https://openalex.org/W2034709854","https://openalex.org/W2038835389","https://openalex.org/W2041075406","https://openalex.org/W2042038416","https://openalex.org/W2042161439","https://openalex.org/W2042208046","https://openalex.org/W2042537629","https://openalex.org/W2042683011","https://openalex.org/W2042868166","https://openalex.org/W2043104532","https://openalex.org/W2043800489","https://openalex.org/W2043987331","https://openalex.org/W2045229779","https://openalex.org/W2045312983","https://openalex.org/W2045390477","https://openalex.org/W2047370470","https://openalex.org/W2048027358","https://openalex.org/W2049927822","https://openalex.org/W2050036363","https://openalex.org/W2051301499","https://openalex.org/W2053921507","https://openalex.org/W2054112641","https://openalex.org/W2054938569","https://openalex.org/W2057557143","https://openalex.org/W2057809738","https://openalex.org/W2058331365","https://openalex.org/W2058606051","https://openalex.org/W2059124184","https://openalex.org/W2060128665","https://openalex.org/W2061970901","https://openalex.org/W2063051980","https://openalex.org/W2063749178","https://openalex.org/W2064640971","https://openalex.org/W2064799108","https://openalex.org/W2065468254","https://openalex.org/W2066558479","https://openalex.org/W2067359199","https://openalex.org/W2068061404","https://openalex.org/W2068952217","https://openalex.org/W2072232259","https://openalex.org/W2072268299","https://openalex.org/W2072384179","https://openalex.org/W2073435581","https://openalex.org/W2074672488","https://openalex.org/W2076579607","https://openalex.org/W2078250306","https://openalex.org/W2078546046","https://openalex.org/W2079139796","https://openalex.org/W2079362770","https://openalex.org/W2079660420","https://openalex.org/W2080206806","https://openalex.org/W2080762678","https://openalex.org/W2080900526","https://openalex.org/W2081241968","https://openalex.org/W2081434876","https://openalex.org/W2081500697","https://openalex.org/W2083556566","https://openalex.org/W2083631490","https://openalex.org/W2084291206","https://openalex.org/W2084500917","https://openalex.org/W2085936016","https://openalex.org/W2087112240","https://openalex.org/W2090102169","https://openalex.org/W2090163639","https://openalex.org/W2091990097","https://openalex.org/W2092557691","https://openalex.org/W2093203564","https://openalex.org/W2094154670","https://openalex.org/W2094207502","https://openalex.org/W2094406134","https://openalex.org/W2095720502","https://openalex.org/W2095773179","https://openalex.org/W2095847632","https://openalex.org/W2097677851","https://openalex.org/W2097830168","https://openalex.org/W2098753357","https://openalex.org/W2100547118","https://openalex.org/W2101787166","https://openalex.org/W2102697938","https://openalex.org/W2103888323","https://openalex.org/W2104418170","https://openalex.org/W2104825124","https://openalex.org/W2105779371","https://openalex.org/W2107673518","https://openalex.org/W2108155348","https://openalex.org/W2108435955","https://openalex.org/W2108729511","https://openalex.org/W2110971703","https://openalex.org/W2111117400","https://openalex.org/W2111911518","https://openalex.org/W2112355201","https://openalex.org/W2112422039","https://openalex.org/W2112856303","https://openalex.org/W2113216559","https://openalex.org/W2115299313","https://openalex.org/W2115364257","https://openalex.org/W2116998724","https://openalex.org/W2118381070","https://openalex.org/W2118816397","https://openalex.org/W2118858814","https://openalex.org/W2119410610","https://openalex.org/W2121473161","https://openalex.org/W2122647885","https://openalex.org/W2127216982","https://openalex.org/W2129447731","https://openalex.org/W2129464080","https://openalex.org/W2132254218","https://openalex.org/W2134676097","https://openalex.org/W2135359106","https://openalex.org/W2136795074","https://openalex.org/W2137336593","https://openalex.org/W2138596623","https://openalex.org/W2139041338","https://openalex.org/W2139717119","https://openalex.org/W2141678261","https://openalex.org/W2142538185","https://openalex.org/W2142906420","https://openalex.org/W2145602609","https://openalex.org/W2146936549","https://openalex.org/W2148080069","https://openalex.org/W2149714337","https://openalex.org/W2151025275","https://openalex.org/W2151053125","https://openalex.org/W2151213765","https://openalex.org/W2151987671","https://openalex.org/W2152465977","https://openalex.org/W2153092930","https://openalex.org/W2153245357","https://openalex.org/W2153263227","https://openalex.org/W2153875441","https://openalex.org/W2154778382","https://openalex.org/W2155111071","https://openalex.org/W2155639918","https://openalex.org/W2157097093","https://openalex.org/W2159010478","https://openalex.org/W2159813710","https://openalex.org/W2160719120","https://openalex.org/W2160950389","https://openalex.org/W2161839431","https://openalex.org/W2164148159","https://openalex.org/W2165753570","https://openalex.org/W2165817065","https://openalex.org/W2167727535","https://openalex.org/W2167800708","https://openalex.org/W2168039900","https://openalex.org/W2168540621","https://openalex.org/W2170783786","https://openalex.org/W2172143029","https://openalex.org/W2173833672","https://openalex.org/W2184933850","https://openalex.org/W2253598100","https://openalex.org/W2315907040","https://openalex.org/W2331697328","https://openalex.org/W2333388184","https://openalex.org/W2395286598","https://openalex.org/W2399064450","https://openalex.org/W2400844733","https://openalex.org/W2411546224","https://openalex.org/W2411736856","https://openalex.org/W2412263542","https://openalex.org/W2414548278","https://openalex.org/W2768146862","https://openalex.org/W4322703177"],"related_works":["https://openalex.org/W1983705436","https://openalex.org/W2045229779","https://openalex.org/W2145602609","https://openalex.org/W99807885","https://openalex.org/W2080762678","https://openalex.org/W2731879171","https://openalex.org/W2151987671","https://openalex.org/W2281984878","https://openalex.org/W2328090920","https://openalex.org/W2073435581"],"abstract_inverted_index":{"Sepsis,":[0],"a":[1,9,75,83,171,224,304],"systemic":[2],"inflammatory":[3],"response":[4],"to":[5,25,43,69,82,234],"an":[6],"infection,":[7],"is":[8,54,301],"significant":[10],"cause":[11],"of":[12,31,38,50,61,97,125,247,249,287,289,330],"morbidity":[13],"and":[14,27,108,119,145,148,166,241,274,314],"mortality":[15],"worldwide.":[16],"The":[17],"microcirculation":[18],"during":[19],"sepsis":[20],"fails,":[21],"in":[22,115,121,150,174,177,227,253,261,269,277,316,321],"part,":[23],"due":[24],"microthrombosis":[26],"the":[28,48,62,79,91,95,103,116,138,209,245,254,285,293,322],"resulting":[29],"plugging":[30,81,300],"capillaries,":[32],"precipitating":[33],"organ":[34],"failure.":[35],"Intravenous":[36],"injection":[37],"ascorbate":[39,98,126,154,202,250,290,296],"has":[40,218,223],"been":[41,219],"shown":[42,220],"reduce":[44],"capillary":[45,80,299],"plugging,":[46],"however":[47],"mechanism":[49],"this":[51,70],"protective":[52,225],"effect":[53,96,124,248,288],"unclear.":[55],"We":[56,179,204],"hypothesized":[57],"that":[58,73,181,208,221,230,266,292],"ascorbate-mediated":[59],"destabilization":[60],"microthrombi":[63],"through":[64,297,303],"promoting":[65],"fibrinolysis":[66],"could":[67],"contribute":[68],"protection.\\nWe":[71],"showed":[72],"streptokinase,":[74],"pro-fibrinolytic":[76],"agent,":[77],"reduced":[78,298],"similar":[84],"degree":[85],"as":[86,310,327],"ascorbate.":[87,192,333],"This":[88],"similarity":[89],"provided":[90],"impetus":[92],"for":[93],"studying":[94],"on":[99,129,251],"fibrinolysis.":[100],"Sepsis":[101,135],"increased":[102,137,235,238,242],"urokinase":[104],"plasminogen":[105,110,139],"activator":[106,111,140],"(u-PA)":[107],"tissue":[109,255],"(t-PA)":[112],"mRNA":[113,144],"expression":[114,133,147,273],"skeletal":[117],"muscle":[118],"liver":[120],"mice.":[122],"No":[123],"was":[127,188,199,214],"observed":[128,180,265],"u-PA":[130],"or":[131],"t-PA":[132],"levels.":[134],"also":[136,206],"inhibitor":[141],"1":[142],"(PAI-1)":[143],"protein":[146],"activity":[149],"these":[151,158],"tissues,":[152],"but":[153],"did":[155],"not":[156,189,281,302],"affect":[157],"increases.\\nThe":[159],"local":[160],"PAI-1":[161,182,195,210,222,231,252,272],"release":[162,196,211],"by":[163,184,191,201,283,295,332],"both":[164],"platelets":[165,198,213],"endothelial":[167,186],"cells":[168,187],"may":[169,256],"play":[170],"critical":[172],"role":[173,226,260],"microthrombus":[175],"formation":[176],"capillaries.":[178],"released":[183],"isolated":[185],"affected":[190,282],"However,":[193],"thrombin-induced":[194],"from":[197,212],"inhibited":[200],"pH-dependently.":[203],"have":[205],"discovered":[207],"nitric":[215],"oxide":[216],"independent.\\nIt":[217],"sepsis,":[228],"namely":[229],"knockout":[232],"leads":[233],"bacterial":[236,270],"content,":[237],"neutrophil":[239],"apoptosis":[240],"mortality.":[243],"Therefore,":[244],"lack":[246,286],"maintain":[257],"PAI-1\u2019s":[258],"beneficial":[259],"sepsis.":[262],"Consistently,":[263],"we":[264],"sepsis-induced":[267],"increases":[268],"count,":[271],"myeloperoxidase":[275],"content":[276],"various":[278],"organs":[279],"were":[280],"ascorbate.\\nOverall,":[284],"indicates":[291],"protection":[294,331],"fibrinolytic":[305],"mechanism.":[306],"Other":[307],"mechanisms":[308,329],"such":[309],"platelet-endothelial":[311],"cell":[312,319],"adhesion":[313],"changes":[315],"red":[317],"blood":[318],"deformability":[320],"capillaries":[323],"should":[324],"be":[325],"explored":[326],"possible":[328]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
