{"id":"https://openalex.org/W96076501","doi":null,"title":"Abstract 14660: Severe Pulmonary Hypertension and Right Ventricular Dysfunction in Rats are Associated with Changes in Ubiquitin Proteasome System","display_name":"Abstract 14660: Severe Pulmonary Hypertension and Right Ventricular Dysfunction in Rats are Associated with Changes in Ubiquitin Proteasome System","publication_year":2011,"publication_date":"2011-11-22","ids":{"openalex":"https://openalex.org/W96076501","mag":"96076501"},"language":"en","primary_location":{"id":"mag:96076501","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.124.suppl_21.A14660","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049788059","display_name":"Soban Umar","orcid":"https://orcid.org/0000-0001-8036-3079","observed_orcids":["https://orcid.org/0000-0001-8036-3079"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soban Umar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8036-3079","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023812721","display_name":"Shannamar Dewey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shannamar Dewey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014409491","display_name":"Andrea Iorga","orcid":"https://orcid.org/0000-0001-7809-9184","observed_orcids":["https://orcid.org/0000-0001-7809-9184"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea Iorga","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7809-9184","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072698091","display_name":"Aldrin V. Gomes","orcid":"https://orcid.org/0000-0002-9819-3036","observed_orcids":["https://orcid.org/0000-0002-9819-3036"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aldrin V. Gomes","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9819-3036","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5016874335","display_name":"Mansoureh Eghbali","orcid":"https://orcid.org/0000-0002-6252-9976","observed_orcids":["https://orcid.org/0000-0002-6252-9976"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mansoureh Eghbali","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6252-9976","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"124","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.7656000256538391,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.7656000256538391,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.22499999403953552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-hypertension","display_name":"pulmonary hypertension","score":0.8320000171661377},{"id":"https://openalex.org/keywords/right-ventricular-dysfunction","display_name":"right ventricular dysfunction","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ubiquitin-proteasome-system","display_name":"ubiquitin-proteasome system","score":0.9929999709129333},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.9340000152587891}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9577632546424866},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.7203436493873596},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6017231345176697},{"id":"https://openalex.org/C27740335","wikidata":"https://www.wikidata.org/wiki/Q14878333","display_name":"Proteasome","level":2,"score":0.5951570868492126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5417718291282654},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.524137556552887},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.5239800810813904},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.10502627491950989},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06581002473831177},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:96076501","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.124.suppl_21.A14660","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.49000000953674316,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2125939035","https://openalex.org/W3176043961","https://openalex.org/W2587129949","https://openalex.org/W2060667552","https://openalex.org/W2980680280","https://openalex.org/W2058727367","https://openalex.org/W2920107878","https://openalex.org/W139283703","https://openalex.org/W2769427840","https://openalex.org/W1538864134","https://openalex.org/W2917071653","https://openalex.org/W1968975143","https://openalex.org/W2558690825","https://openalex.org/W2887461036","https://openalex.org/W68713677","https://openalex.org/W2061606124","https://openalex.org/W2357790135","https://openalex.org/W3199475134","https://openalex.org/W2313629054","https://openalex.org/W3159364440"],"abstract_inverted_index":{"Introduction.":[0],"Ubiquitin-proteasome":[1],"system":[2],"(UPS)":[3],"is":[4],"responsible":[5],"for":[6],"degradation":[7],"of":[8,16,21],"intracellular":[9],"proteins.":[10],"UPS":[11],"maintains":[12],"a":[13],"dynamic":[14],"equilibrium":[15],"proteins":[17],"and":[18,23],"prevents":[19],"accumulation":[20],"damaged":[22],"mi...":[24]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-14T23:32:53.992493","created_date":"2025-10-10T00:00:00"}