{"id":"https://openalex.org/W95857463","doi":null,"title":"Expression Level of Kita, Kitb, Kitla, and Kitlb in Zebrafish Gastrointestional Tract","display_name":"Expression Level of Kita, Kitb, Kitla, and Kitlb in Zebrafish Gastrointestional Tract","publication_year":2011,"publication_date":"2011-06-01","ids":{"openalex":"https://openalex.org/W95857463","mag":"95857463"},"language":"en","primary_location":{"id":"pmh:oai:soar.suny.edu:20.500.12648/4498","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.12648/4498","pdf_url":null,"source":{"id":"https://openalex.org/S4306400078","display_name":"SUNY Digital Repository Support (State University of New York System)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I63190737","host_organization_name":"University at Buffalo, State University of New York","host_organization_lineage":["https://openalex.org/I63190737"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020413360","display_name":"Jennifer B. Strouse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jennifer B. Strouse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5020413360"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12237","display_name":"Congenital gastrointestinal and neural anomalies","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kit-receptor","display_name":"KIT receptor","score":0.6449999809265137},{"id":"https://openalex.org/keywords/kita","display_name":"Kita","score":0.8970000147819519},{"id":"https://openalex.org/keywords/interstitial-cells-of-cajal","display_name":"interstitial cells of Cajal","score":0.9490000009536743},{"id":"https://openalex.org/keywords/gastrointestinal-motility","display_name":"gastrointestinal motility","score":0.9330000281333923},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.7129999995231628},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.5680000185966492},{"id":"https://openalex.org/keywords/tmem16a","display_name":"TMEM16A","score":0.765999972820282},{"id":"https://openalex.org/keywords/slow-waves","display_name":"slow waves","score":0.5210000276565552},{"id":"https://openalex.org/keywords/enteric-neurons","display_name":"enteric neurons","score":0.6010000109672546},{"id":"https://openalex.org/keywords/smooth-muscle-cells","display_name":"smooth muscle cells","score":0.734000027179718},{"id":"https://openalex.org/keywords/gastrointestinal-stromal-tumor","display_name":"gastrointestinal stromal tumor","score":0.5809999704360962},{"id":"https://openalex.org/keywords/stem-cell-factor","display_name":"stem cell factor","score":0.3449999988079071},{"id":"https://openalex.org/keywords/developmental-timing","display_name":"developmental timing","score":0.36000001430511475},{"id":"https://openalex.org/keywords/constipation","display_name":"constipation","score":0.39399999380111694},{"id":"https://openalex.org/keywords/delayed-gastric-emptying","display_name":"delayed gastric emptying","score":0.8360000252723694},{"id":"https://openalex.org/keywords/bloating","display_name":"bloating","score":0.5950000286102295},{"id":"https://openalex.org/keywords/receptor-tyrosine-kinase-signaling","display_name":"receptor tyrosine kinase signaling","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.8445811867713928},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5827120542526245},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38463830947875977},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.17621952295303345},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14586693048477173},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10483521223068237},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.05107143521308899}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:soar.suny.edu:20.500.12648/4498","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.12648/4498","pdf_url":null,"source":{"id":"https://openalex.org/S4306400078","display_name":"SUNY Digital Repository Support (State University of New York System)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I63190737","host_organization_name":"University at Buffalo, State University of New York","host_organization_lineage":["https://openalex.org/I63190737"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":"thesis"},{"id":"mag:95857463","doi":null,"is_oa":false,"landing_page_url":"http://digitalcommons.brockport.edu/cgi/viewcontent.cgi?article=1002&context=bio_theses","pdf_url":null,"source":{"id":"https://openalex.org/S4306525032","display_name":"published","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W645508545","https://openalex.org/W1556198965","https://openalex.org/W1559908984","https://openalex.org/W1577577364","https://openalex.org/W1975411923","https://openalex.org/W1986243430","https://openalex.org/W1987211770","https://openalex.org/W1988530903","https://openalex.org/W1989981798","https://openalex.org/W1991175004","https://openalex.org/W1998447762","https://openalex.org/W2003379238","https://openalex.org/W2007041001","https://openalex.org/W2018171716","https://openalex.org/W2041488113","https://openalex.org/W2047966069","https://openalex.org/W2051616442","https://openalex.org/W2063201232","https://openalex.org/W2073390510","https://openalex.org/W2088478091","https://openalex.org/W2099217384","https://openalex.org/W2104455852","https://openalex.org/W2109193947","https://openalex.org/W2128064909","https://openalex.org/W2143742454","https://openalex.org/W2152827122","https://openalex.org/W2155551954","https://openalex.org/W2158274448","https://openalex.org/W2159970653","https://openalex.org/W2160505438","https://openalex.org/W2161080750","https://openalex.org/W2168420558","https://openalex.org/W2170943429","https://openalex.org/W2187037224","https://openalex.org/W2188930007","https://openalex.org/W2253046940"],"related_works":["https://openalex.org/W2790874786","https://openalex.org/W2099217384","https://openalex.org/W1991736258","https://openalex.org/W2891659267","https://openalex.org/W2968546848","https://openalex.org/W2082196064","https://openalex.org/W2029869131","https://openalex.org/W846512561","https://openalex.org/W4401509971","https://openalex.org/W2791655193"],"abstract_inverted_index":{"Gastrointestinal":[0],"(GI)":[1],"motility":[2,29,229],"is":[3,19,30,65,81,124,133,150,185,203,218,226,435],"the":[4,75,90,94,153,166,176,186,207,216,234,338,387,419,430],"muscular":[5],"contractions":[6],"that":[7,227,315,412,434],"move":[8],"intestinal":[9],"contents":[10],"in":[11,93,110,138,141,165,233,281,307,334,404,418,429,437],"an":[12],"anterograde":[13],"(mouth":[14],"to":[15,89,151,206,222,253,382,401,441],"anus)":[16],"direction":[17],"and":[18,24,33,44,57,63,101,117,129,155,163,178,197,211,245,257,265,280,294,317,393,415,439,448,461,470,474],"necessary":[20,125],"for":[21,126,147,249,289,346,366,389],"nutrient":[22],"absorption":[23],"elimination":[25],"of":[26,39,78,108,119,159,182,194,261,331,342,349,427,466],"waste.":[27],"GI":[28,50,95,111,143,209,228,243,378,408,421,432],"highly":[31],"coordinated":[32],"rhythmic":[34],"contraction":[35,59],"patterns.":[36],"Interstitial":[37],"cells":[38,47,56,428],"Cajal":[40],"(ICC),":[41],"enteric":[42],"neurons,":[43],"smooth":[45],"muscle":[46],"all":[48,347],"regulate":[49],"motility.":[51],"ICC":[52,61,109,127,136,195,442],"function":[53],"as":[54,247,287,298,361],"pacemaker":[55],"determine":[58,152],"frequency.":[60],"growth":[62,128],"development":[64,137,196,335],"influenced":[66],"by":[67,444],"Kit,":[68],"a":[69,82,190,299,321,362,425],"tyrosine":[70],"kinase":[71],"receptor":[72,116],"located":[73],"on":[74],"plasma":[76],"membrane":[77],"ICC.":[79],"TMEM16A":[80,355,403,469],"calcium":[83],"activated":[84],"chloride":[85],"channel":[86],"which":[87,303,385],"contributes":[88],"slow":[91],"wave":[92],"tract.":[96,409,422],"Constipation,":[97],"delayed":[98],"gastric":[99],"emptying,":[100],"bloating":[102],"have":[103],"been":[104],"correlated":[105],"with":[106,121],"deficits":[107],"tissues.":[112],"A":[113],"functional":[114,300,322],"Kit":[115,120,122,445],"stimulation":[118],"ligand":[123],"development.":[130],"However,":[131],"little":[132],"known":[134],"about":[135],"adults":[139],"or":[140],"developing":[142],"tissue.":[144],"The":[145,199,310],"objective":[146],"this":[148,223],"project":[149],"relative":[154,179,311],"temporal":[156,177,258,449],"expression":[157,180,259,312,326,330,341,345,450],"levels":[158,260],"Kita,":[160,262],"Kitb,":[161,263,343],"Kitla,":[162,264],"Kitlb":[164,266,318],"zebrafish":[167,200,217,242,377,407,420,431],"model":[168,201,224],"system":[169,202,225],"at":[170,212,269,352,456,472],"several":[171],"developmental":[172],"time":[173,214,291,463,476],"points.":[174,464,477],"Understanding":[175],"pattern":[181],"these":[183],"genes":[184,348],"first":[187,305],"step":[188],"towards":[189],"more":[191,363],"complete":[192],"understanding":[193],"turnover.":[198],"anatomically":[204],"similar":[205,436],"human":[208],"tract":[210,379,433],"early":[213,333,339],"points":[215],"transparent.":[219],"One":[220],"advantage":[221],"may":[230],"be":[231],"examined":[232],"intact":[235],"larvae.":[236],"RNA":[237,373],"was":[238,267,304,359,380,451],"isolated":[239,374,455],"from":[240,375],"dissected":[241,376],"tissues":[244,284],"used":[246,381,400],"template":[248,288,388],"reverse":[250,390],"transcriptase":[251,391],"reactions":[252],"make":[254,383],"eDNA.":[255],"Relative":[256,447],"determined":[268,452],"5":[270],"days":[271],"post":[272],"fertilization":[273],"(dpf),":[274],"7":[275],"dpf,":[276,278],"11":[277,353],"28dpf,":[279,460],"adult":[282,462,475],"gut":[283],"using":[285,453],"eDNA":[286,384],"real":[290],"PCR.":[292],"Kita":[293],"Kitla":[295],"were":[296,399],"confirmed":[297],"receptor/ligand":[301,323],"pair":[302],"identified":[306,360],"melanocyte":[308],"migration19.":[309],"data":[313,327],"suggests":[314],"Kitb":[316,332],"are":[319],"also":[320],"pair.":[324],"Temporal":[325],"shows":[328],"high":[329,340],"(5dpf).":[336],"Besides":[337],"gene":[344],"interest":[350],"peak":[351],"dpf.":[354],"(also":[356],"called":[357],"ANOI)":[358],"accurate":[364],"marker":[365],"gastrointestinal":[367],"stromal":[368],"tumors":[369],"(GIST)":[370],"than":[371],"Kit24.":[372],"became":[386],"(RT)-PCR":[392],"real-tin1e":[394],"PCR":[395],"(q-PCR).":[396],"Anti-ANOI":[397],"antibodies":[398],"identify":[402],"dissected,":[405],"fixed":[406],"RT-PCR":[410],"showed":[411],"TMEM16A,":[413],"B,":[414],"Care":[416],"expressed":[417],"Immunohistochemistry":[423],"identifies":[424],"network":[426],"morphology":[438],"location":[440],"stained":[443],"antibodies.":[446],"samples":[454],"5,":[457],"7,":[458],"11,":[459],"Expression":[465],"TMEM16B":[467],"dominates":[468],"B":[471],"28dpf":[473]},"counts_by_year":[],"updated_date":"2026-09-01T08:31:24.195828","created_date":"2016-06-24T00:00:00"}
