{"id":"https://openalex.org/W958458751","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","title":"Abstract 707: Nonuniformity of Left Ventricular Apical-to-Basal Diastolic Lengthening in Patients with Hypertrophic Nonobstructive Cardiomyopathy","display_name":"Abstract 707: Nonuniformity of Left Ventricular Apical-to-Basal Diastolic Lengthening in Patients with Hypertrophic Nonobstructive Cardiomyopathy","publication_year":2008,"publication_date":"2008-10-28","ids":{"openalex":"https://openalex.org/W958458751","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","mag":"958458751"},"language":"en","primary_location":{"id":"doi:10.1161/circ.118.suppl_18.s_603-b","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109133237","display_name":"Takeo Tanaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeo Tanaka","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006072526","display_name":"Kazuya Murata","orcid":"https://orcid.org/0000-0003-2315-2923","observed_orcids":["https://orcid.org/0000-0003-2315-2923"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuya Murata","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076391956","display_name":"Eizo Akagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eizo Akagawa","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042452953","display_name":"Chikage Kihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chikage Kihara","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064274363","display_name":"Hiroko Yoshino","orcid":"https://orcid.org/0000-0002-2087-128X","observed_orcids":["https://orcid.org/0000-0002-2087-128X"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroko Yoshino","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034490483","display_name":"Yoshio Nose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshio Nose","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008698678","display_name":"Yasuhiro Fukagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuhiro Fukagawa","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067652483","display_name":"Takehisa Susa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takehisa Susa","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101800181","display_name":"Shinichi Okuda","orcid":"https://orcid.org/0000-0003-2639-5373","observed_orcids":["https://orcid.org/0000-0003-2639-5373"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Okuda","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031835144","display_name":"Yasuaki Wada","orcid":"https://orcid.org/0000-0002-1586-6419","observed_orcids":["https://orcid.org/0000-0002-1586-6419"]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuaki Wada","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105788500","display_name":"Masunori Matsuzaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173915773","display_name":"Yamaguchi University","ror":"https://ror.org/03cxys317","country_code":"JP","type":"education","lineage":["https://openalex.org/I173915773"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masunori Matsuzaki","raw_affiliation_strings":["Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yamaguchi Univ Graduate Sch of Medicine, Ube, Japan","institution_ids":["https://openalex.org/I173915773"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I173915773"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"118","issue":"suppl_18","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.8726000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.12330000102519989,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertrophic-cardiomyopathy","display_name":"hypertrophic cardiomyopathy","score":0.8650000095367432},{"id":"https://openalex.org/keywords/non-obstructive-hypertrophic-cardiomyopathy","display_name":"non-obstructive hypertrophic cardiomyopathy","score":0.8830000162124634},{"id":"https://openalex.org/keywords/diastolic-function","display_name":"diastolic function","score":0.5450000166893005},{"id":"https://openalex.org/keywords/isovolumic-relaxation-time","display_name":"isovolumic relaxation time","score":0.906000018119812},{"id":"https://openalex.org/keywords/early-diastole","display_name":"early diastole","score":0.6949999928474426},{"id":"https://openalex.org/keywords/left-ventricular-filling","display_name":"left ventricular filling","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C2780185194","wikidata":"https://www.wikidata.org/wiki/Q1364270","display_name":"Hypertrophic cardiomyopathy","level":2,"score":0.78537917137146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7835658192634583},{"id":"https://openalex.org/C67139541","wikidata":"https://www.wikidata.org/wiki/Q2858200","display_name":"Apex (geometry)","level":2,"score":0.7641786336898804},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7237350344657898},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6602587699890137},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.6482776403427124},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.5964650511741638},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.29727011919021606},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circ.118.suppl_18.s_603-b","doi":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.118.suppl_18.s_603-b","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2010752834","https://openalex.org/W2136573815","https://openalex.org/W2126523062","https://openalex.org/W2165561827","https://openalex.org/W2462164761","https://openalex.org/W2005535196","https://openalex.org/W4240065761","https://openalex.org/W2492784800","https://openalex.org/W2083093071","https://openalex.org/W2736656583"],"abstract_inverted_index":{"Quantification":[0],"of":[1,27,40,90,119,123,185,200,220,230],"left":[2,202],"ventricular":[3,203],"(LV)":[4],"apex-to-base":[5,213],"dispersion":[6],"has":[7],"been":[8],"feasible":[9],"with":[10,34,66],"two-dimensional":[11],"echocardiographic":[12],"tissue":[13],"tracking":[14],"system":[15],"(2DTT,":[16],"Hitachi":[17],"EUB7500),":[18],"which":[19],"based":[20],"on":[21,77],"pattern":[22],"matching":[23],"algorithm.":[24],"Although":[25,148],"impairment":[26,229],"LV":[28,41,51,60,143,195,221,231],"relaxation":[29,135,232],"was":[30,138,171,192,208],"characterized":[31],"in":[32,63,83,131,157,169,210,218,233],"patients":[33,65],"hypertrophic":[35],"cardiomyopathy":[36],"(HCM),":[37],"the":[38,87,100,112,117,120,165],"behavior":[39],"apical":[42,59,150,166,216],"and":[43,47,58,69,86,95,103,145,151,190],"basal":[44,57,152],"diastolic":[45],"lengthening":[46,104,125,204,222],"its":[48],"relation":[49],"to":[50,116,174,194],"filling":[52],"are":[53],"unknown.":[54],"We":[55],"obtained":[56],"short-axis":[61],"views":[62],"22":[64],"non-obstructive":[67],"HCM":[68,170],"25":[70],"healthy":[71],"volunteers":[72],"(N).":[73],"Eight":[74],"equiangular":[75],"points":[76],"endo-myocardium":[78],"at":[79],"end-diastole":[80],"were":[81,93,106,129,155],"placed":[82],"each":[84,132],"view,":[85],"shortening":[88,102],"ratios":[89],"four":[91],"directions":[92],"calculated":[94],"averaged":[96],"by":[97,140],"2DTT.":[98],"Then,":[99],"time-LV":[101],"curves":[105],"obtained.":[107],"The":[108,182],"time":[109,136,183],"intervals":[110],"from":[111],"aortic":[113],"valve":[114],"closure":[115],"point":[118],"first":[121],"40%":[122],"peak":[124],"(T":[126],"40":[127,154,168,187],")":[128],"measured":[130,139],"view.":[133],"Isovolumic":[134],"(IRT)":[137],"pulsed":[141],"Doppler":[142],"in-":[144],"out-flow":[146],"recordings.":[147],"both":[149],"T":[153,167,186],"similar":[156],"N":[158],"(145.8\u00b138.4":[159],"vs.":[160,177],"134.3\u00b134.2msec":[161],"0.5":[162,179],",":[163,180],"ns.),":[164],"longer":[172],"compared":[173],"base":[175,191],"(118.7\u00b151.1":[176],"168.8\u00b152.5msec":[178],"p<0.0001).":[181,198],"difference":[184],"between":[188],"apex":[189],"related":[193],"IRT":[196],"(r=0.59,":[197],"Nonuniformity":[199],"apical-to-basal":[201],"during":[205],"early":[206],"diastole":[207],"present":[209],"HCM.":[211,234],"This":[212],"dispersion,":[214],"especially":[215],"delay":[217],"timing":[219],"may":[223],"have":[224],"a":[225],"physiologic":[226],"importance":[227],"for":[228]},"counts_by_year":[],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}