{"id":"https://openalex.org/W95830692","doi":null,"title":"Rapid eye movement sleep measures of Alzheimer's-type dementia patients and optimally healthy aged individuals.","display_name":"Rapid eye movement sleep measures of Alzheimer's-type dementia patients and optimally healthy aged individuals.","publication_year":1984,"publication_date":"1984-05-01","ids":{"openalex":"https://openalex.org/W95830692","mag":"95830692","pmid":"https://pubmed.ncbi.nlm.nih.gov/6733181"},"language":"en","primary_location":{"id":"pmid:6733181","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6733181","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological psychiatry","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013037067","display_name":"Michael V. Vitiello","orcid":"https://orcid.org/0000-0002-9776-0473","observed_orcids":["https://orcid.org/0000-0002-9776-0473"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M V Vitiello","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012642822","display_name":"John A. Bokan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J A Bokan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060014836","display_name":"Walter A. Kukull","orcid":"https://orcid.org/0000-0001-8761-9014","observed_orcids":["https://orcid.org/0000-0001-8761-9014"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W A Kukull","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068720082","display_name":"Roberto Mu\u00f1iz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R L Muniz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023808097","display_name":"R. G. Smallwood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R G Smallwood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113492184","display_name":"Patricia N. Prinz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P N Prinz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9621,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.71822065,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"19","issue":"5","first_page":"721","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.5410000085830688,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.38839998841285706,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.06449999660253525,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rem-sleep","display_name":"REM sleep","score":0.8360000252723694},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9419999718666077},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.7300000190734863},{"id":"https://openalex.org/keywords/rem-latency","display_name":"REM latency","score":0.9369999766349792},{"id":"https://openalex.org/keywords/rem-density","display_name":"REM density","score":0.8370000123977661},{"id":"https://openalex.org/keywords/dementia-severity","display_name":"dementia severity","score":0.7749999761581421},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.828000009059906},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.6489999890327454},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.5519999861717224},{"id":"https://openalex.org/keywords/sleep-architecture","display_name":"sleep architecture","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.8208005428314209},{"id":"https://openalex.org/C2779213384","wikidata":"https://www.wikidata.org/wiki/Q211402","display_name":"Rapid eye movement sleep","level":3,"score":0.6480851173400879},{"id":"https://openalex.org/C153050134","wikidata":"https://www.wikidata.org/wiki/Q760256","display_name":"Eye movement","level":2,"score":0.6210411787033081},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6017003059387207},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.558537483215332},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5569540858268738},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5067585110664368},{"id":"https://openalex.org/C82876162","wikidata":"https://www.wikidata.org/wiki/Q17096504","display_name":"Latency (audio)","level":2,"score":0.41700437664985657},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.4114946722984314},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.34885090589523315},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32469233870506287},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2254784107208252},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19968339800834656},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:6733181","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6733181","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological psychiatry","raw_type":"Journal Article"},{"id":"mag:95830692","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6733181","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2047764959","https://openalex.org/W1967576578","https://openalex.org/W2042938678","https://openalex.org/W2400844645","https://openalex.org/W1993374091","https://openalex.org/W2414170536","https://openalex.org/W1966600045","https://openalex.org/W2007092083","https://openalex.org/W2121099423","https://openalex.org/W4406874904"],"abstract_inverted_index":{"It":[0],"has":[1],"been":[2],"suggested":[3],"that":[4,83,169],"rapid":[5],"eye":[6],"movement":[7],"(REM)":[8],"sleep":[9,38,85,97,174],"measures":[10,29,86,175],"may":[11,176],"be":[12],"useful":[13,178],"in":[14,31,117,124,165,179,187],"the":[15,36,95,138,144,180],"differential":[16,181],"diagnosis":[17,182],"of":[18,27,39,94,120,140,151,155,183],"affective":[19],"disorders.":[20],"To":[21],"determine":[22],"what":[23],"changes,":[24],"if":[25],"any,":[26],"REM":[28,37,70,72,74,77,84,96,109,112,125,127,141,162,173],"occur":[30],"Alzheimer's":[32,54],"dementia":[33,50,184],"we":[34],"examined":[35],"nine":[40,43,45,48],"control":[41,131],"and":[42,47,58,60,76,111,126,132,185],"mild,":[44],"moderate,":[46],"severe":[49],"subjects":[51,105],"with":[52,170],"probable":[53],"disease":[55],"(AD).":[56],"Control":[57],"mild":[59,91,103],"moderate":[61],"AD":[62,104,134],"groups":[63],"were":[64,79,114],"screened":[65],"to":[66,160],"exclude":[67],"major":[68,166],"depression.":[69],"latency,":[71],"time,":[73],"activity,":[75],"density":[78,142],"examined.":[80],"Results":[81],"indicated":[82],"are":[87],"minimally":[88],"affected":[89,116,148],"by":[90,149],"dementia.":[92,121,152],"None":[93],"variables":[98],"reported":[99],"here":[100],"successfully":[101,129],"discriminated":[102],"from":[106],"controls.":[107],"However,":[108],"time":[110,123],"latency":[113,128],"significantly":[115],"later":[118],"stages":[119],"Total":[122],"classified":[130],"moderate-severe":[133],"patients.":[135],"In":[136],"addition,":[137],"pattern":[139],"across":[143],"night":[145],"was":[146],"also":[147],"severity":[150],"The":[153],"results":[154],"this":[156],"study,":[157],"when":[158],"compared":[159],"published":[161],"measure":[163],"findings":[164],"depression,":[167],"indicate":[168],"proper":[171],"cautions":[172],"prove":[177],"depression":[186],"geriatric":[188],"patient":[189],"populations.":[190]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}