{"id":"https://openalex.org/W954047932","doi":"https://doi.org/10.1007/978-1-4615-5771-5_21","title":"Is Methioninase Useful for the Prevention of Hyperhomocysteinemia-Associated Cardiovascular Disease?","display_name":"Is Methioninase Useful for the Prevention of Hyperhomocysteinemia-Associated Cardiovascular Disease?","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W954047932","doi":"https://doi.org/10.1007/978-1-4615-5771-5_21","mag":"954047932"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4615-5771-5_21","doi":"https://doi.org/10.1007/978-1-4615-5771-5_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-5771-5_21","pdf_url":null,"source":{"id":"https://openalex.org/S2764412464","display_name":"Developments in cardiovascular medicine","issn_l":"0166-9842","issn":["0166-9842","2542-8373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Cardiovascular Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2145245816","display_name":"Homocysteine Metabolism: From Basic Science to Clinical Medicine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040819666","display_name":"Robert M. Hoffman","orcid":"https://orcid.org/0000-0002-0049-0041","observed_orcids":["https://orcid.org/0000-0002-0049-0041"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Robert M. Hoffman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5040819666"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13732394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"155","last_page":"156"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13551","display_name":"Biochemical effects in animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9240000247955322},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.847000002861023},{"id":"https://openalex.org/keywords/arteriosclerosis","display_name":"arteriosclerosis","score":0.9430000185966492},{"id":"https://openalex.org/keywords/pseudomonas-putida","display_name":"Pseudomonas putida","score":0.8619999885559082},{"id":"https://openalex.org/keywords/enzyme-therapy","display_name":"enzyme therapy","score":0.7570000290870667},{"id":"https://openalex.org/keywords/acute-intervention","display_name":"acute intervention","score":0.6140000224113464},{"id":"https://openalex.org/keywords/vitamin-b12","display_name":"vitamin B12","score":0.7139999866485596},{"id":"https://openalex.org/keywords/vitamin-b6","display_name":"vitamin B6","score":0.8669999837875366},{"id":"https://openalex.org/keywords/folic-acid","display_name":"folic acid","score":1.0}],"concepts":[{"id":"https://openalex.org/C2776523773","wikidata":"https://www.wikidata.org/wiki/Q1093815","display_name":"Hyperhomocysteinemia","level":3,"score":0.8718142509460449},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.862470805644989},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.8339638710021973},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48876452445983887},{"id":"https://openalex.org/C2780912031","wikidata":"https://www.wikidata.org/wiki/Q180341","display_name":"Methionine","level":3,"score":0.4370138645172119},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.42885464429855347},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3995516896247864},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11799666285514832},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07959529757499695},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4615-5771-5_21","doi":"https://doi.org/10.1007/978-1-4615-5771-5_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-5771-5_21","pdf_url":null,"source":{"id":"https://openalex.org/S2764412464","display_name":"Developments in cardiovascular medicine","issn_l":"0166-9842","issn":["0166-9842","2542-8373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Cardiovascular Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W90081202","https://openalex.org/W1544424898","https://openalex.org/W2030480736","https://openalex.org/W2057881489","https://openalex.org/W2122134113","https://openalex.org/W2332685851","https://openalex.org/W2418346118","https://openalex.org/W2444538184"],"related_works":["https://openalex.org/W2022707180","https://openalex.org/W1968530915","https://openalex.org/W1998358660","https://openalex.org/W2312339914","https://openalex.org/W4360898900","https://openalex.org/W2170703297","https://openalex.org/W1505269095","https://openalex.org/W2126013994","https://openalex.org/W2109804940","https://openalex.org/W7037240232"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}