{"id":"https://openalex.org/W95239080","doi":null,"title":"Developing a distributed research network to conduct population-based studies and safety surveillance.","display_name":"Developing a distributed research network to conduct population-based studies and safety surveillance.","publication_year":2008,"publication_date":"2008-11-06","ids":{"openalex":"https://openalex.org/W95239080","mag":"95239080","pmid":"https://pubmed.ncbi.nlm.nih.gov/18999251"},"language":"en","primary_location":{"id":"pmid:18999251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18999251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA ... Annual Symposium proceedings. AMIA Symposium","raw_type":"Journal Article"},"volume":null,"type":"conference-abstract","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032708536","display_name":"John H. Holmes","orcid":"https://orcid.org/0000-0003-2167-3602","observed_orcids":["https://orcid.org/0000-0003-2167-3602"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H Holmes","raw_affiliation_strings":["University of Pennsylvania School of Medicine, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060381803","display_name":"Jeffrey Scott Brown","orcid":"https://orcid.org/0000-0002-9340-7189","observed_orcids":["https://orcid.org/0000-0002-9340-7189"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Brown","raw_affiliation_strings":["Harvard University, Cambridge, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012370449","display_name":"Sean Hennessy","orcid":"https://orcid.org/0000-0003-4726-9413","observed_orcids":["https://orcid.org/0000-0003-4726-9413"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean Hennessy","raw_affiliation_strings":["University of Pennsylvania, Philadelphia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Philadelphia, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kimberly Lane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Lane","raw_affiliation_strings":["Harvard University, Cambridge, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104110437","display_name":"Robert D. Langer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert D Langer","raw_affiliation_strings":["Massachusetts Institute of Technology, Cambridge, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology, Cambridge, United States","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006440422","display_name":"Ross M Lazarus","orcid":"https://orcid.org/0000-0003-3939-1961","observed_orcids":["https://orcid.org/0000-0003-3939-1961"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ross Lazarus","raw_affiliation_strings":["Harvard University, Cambridge, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043355190","display_name":"Patrick J. O\u2019Connor","orcid":"https://orcid.org/0000-0002-2324-6228","observed_orcids":["https://orcid.org/0000-0002-2324-6228"]},"institutions":[{"id":"https://openalex.org/I1282532422","display_name":"Regions Hospital","ror":"https://ror.org/02bfqd210","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282532422"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick J O'Connor","raw_affiliation_strings":["Regions Hospital, Saint Paul, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regions Hospital, Saint Paul, United States","institution_ids":["https://openalex.org/I1282532422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103451864","display_name":"Brian L. Strom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian L Strom","raw_affiliation_strings":["University of Pennsylvania, Philadelphia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Philadelphia, United States","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014967450","display_name":"Richard G. Platt","orcid":"https://orcid.org/0000-0002-3248-3583","observed_orcids":["https://orcid.org/0000-0002-3248-3583"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Platt","raw_affiliation_strings":["Harvard University, Cambridge, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard University, Cambridge, United States","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"973","last_page":"973"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.7437000274658203,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.7437000274658203,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.045499999076128006,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.028300000354647636,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/distributed-research-networks","display_name":"distributed research networks","score":0.9819999933242798},{"id":"https://openalex.org/keywords/population-based-study","display_name":"population-based study","score":0.7239999771118164},{"id":"https://openalex.org/keywords/pharmacovigilance","display_name":"pharmacovigilance","score":0.8259999752044678},{"id":"https://openalex.org/keywords/comparative-effectiveness-research","display_name":"comparative effectiveness research","score":0.8460000157356262},{"id":"https://openalex.org/keywords/therapeutics","display_name":"therapeutics","score":0.628000020980835},{"id":"https://openalex.org/keywords/antihypertensive-therapy","display_name":"antihypertensive therapy","score":0.7559999823570251},{"id":"https://openalex.org/keywords/health-maintenance-organizations","display_name":"health maintenance organizations","score":0.625},{"id":"https://openalex.org/keywords/network-design","display_name":"network design","score":0.4300000071525574},{"id":"https://openalex.org/keywords/prototype-system","display_name":"prototype system","score":0.4000000059604645}],"concepts":[{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.7034766674041748},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5829033255577087},{"id":"https://openalex.org/C2777532764","wikidata":"https://www.wikidata.org/wiki/Q31855","display_name":"Research center","level":2,"score":0.46927204728126526},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.4488983154296875},{"id":"https://openalex.org/C110354214","wikidata":"https://www.wikidata.org/wiki/Q6314146","display_name":"Engineering management","level":1,"score":0.4420262575149536},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.36129170656204224},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.23172083497047424},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23117172718048096},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003195","descriptor_name":"Computer Communication Networks","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D003299","descriptor_name":"Cooperative Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010414","descriptor_name":"Pennsylvania","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011159","descriptor_name":"Population Surveillance","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017751","descriptor_name":"Safety Management","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:18999251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18999251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA ... Annual Symposium proceedings. AMIA Symposium","raw_type":"Journal Article"},{"id":"mag:95239080","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18999251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1963672880","https://openalex.org/W2122580076","https://openalex.org/W2105398884","https://openalex.org/W2997626061","https://openalex.org/W2787196553","https://openalex.org/W2405799747","https://openalex.org/W7100986315","https://openalex.org/W7014123006","https://openalex.org/W4412063881","https://openalex.org/W2996356967"],"abstract_inverted_index":{"The":[0,63],"Developing":[1],"Evidence":[2],"to":[3,40,48],"Inform":[4],"Decisions":[5],"about":[6],"Effectiveness":[7],"(DEcIDE)":[8],"centers":[9],"at":[10],"the":[11,25,87],"HMO":[12],"Research":[13,19],"Network":[14],"Center":[15],"for":[16,33,83],"Education":[17],"and":[18,24,54,80],"on":[20,77],"Therapeutics":[21],"(HMORN":[22],"CERT)":[23],"University":[26],"of":[27,45,60,73,86],"Pennsylvania":[28],"are":[29],"developing":[30],"a":[31,34,42,67,71],"design":[32],"scalable":[35],"distributed":[36],"research":[37,75],"network":[38],"(DRN)":[39],"support":[41],"wide":[43],"array":[44],"purposes":[46],"related":[47],"therapeutics,":[49],"including":[50],"comparative":[51],"effectiveness,":[52],"safety,":[53],"utilization,":[55],"as":[56,58],"well":[57],"quality":[59],"care":[61],"research.":[62],"project":[64,76],"will":[65],"implement":[66],"system":[68],"prototype,":[69],"conduct":[70],"proof":[72],"principle":[74],"hypertension":[78],"therapy,":[79],"make":[81],"recommendations":[82],"future":[84],"expansion":[85],"network.":[88]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}