{"id":"https://openalex.org/W95237908","doi":"https://doi.org/10.1023/a:1019861721160","title":"Purkinje Cell Size Is Reduced in Cerebellum of Patients with Autism","display_name":"Purkinje Cell Size Is Reduced in Cerebellum of Patients with Autism","publication_year":2002,"publication_date":"2002-04-01","ids":{"openalex":"https://openalex.org/W95237908","doi":"https://doi.org/10.1023/a:1019861721160","mag":"95237908","pmid":"https://pubmed.ncbi.nlm.nih.gov/12363198","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11533743"},"language":"en","primary_location":{"id":"doi:10.1023/a:1019861721160","doi":"https://doi.org/10.1023/a:1019861721160","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1019861721160","pdf_url":null,"source":{"id":"https://openalex.org/S33948212","display_name":"Cellular and Molecular Neurobiology","issn_l":"0272-4340","issn":["0272-4340","1573-6830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Neurobiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11533743","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064921002","display_name":"S. Hossein Fatemi","orcid":"https://orcid.org/0000-0002-6859-2626","observed_orcids":["https://orcid.org/0000-0002-6859-2626"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S. Hossein Fatemi","raw_affiliation_strings":["Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA. fatem002@umn.edu","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA. fatem002@umn.edu","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011297111","display_name":"Amy R. Halt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy R. Halt","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109924968","display_name":"George M. Realmuto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Realmuto","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111864136","display_name":"Julie A. Earle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie Earle","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088111233","display_name":"David A. Kist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Kist","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079436328","display_name":"PAUL D. THURAS","orcid":"https://orcid.org/0000-0003-0888-3074","observed_orcids":["https://orcid.org/0000-0003-0888-3074"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Thuras","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019253015","display_name":"Amelia Merz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amelia Merz","raw_affiliation_strings":["Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Department of Psychiatry, Division of Neuroscience Research, University of Minnesota Medical School, Minneapolis","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064921002"],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":2.9638,"has_fulltext":false,"cited_by_count":357,"citation_normalized_percentile":{"value":0.90365934,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"2","first_page":"171","last_page":"175"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.8889999985694885},{"id":"https://openalex.org/keywords/purkinje-cells","display_name":"Purkinje cells","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.9779999852180481},{"id":"https://openalex.org/keywords/postmortem-brain","display_name":"postmortem brain","score":0.6819999814033508}],"concepts":[{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.8048928380012512},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.6942002177238464},{"id":"https://openalex.org/C2778472085","wikidata":"https://www.wikidata.org/wiki/Q1570272","display_name":"Purkinje cell","level":3,"score":0.6653033494949341},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6480696797370911},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3875472843647003},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3248155415058136},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3202860653400421},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30585604906082153},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.19673284888267517}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001321","descriptor_name":"Autistic Disorder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001321","descriptor_name":"Autistic Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002525","descriptor_name":"Cerebellar Cortex","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":true},{"descriptor_ui":"D002525","descriptor_name":"Cerebellar Cortex","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002525","descriptor_name":"Cerebellar Cortex","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009421","descriptor_name":"Nervous System Malformations","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009421","descriptor_name":"Nervous System Malformations","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011689","descriptor_name":"Purkinje Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D048429","descriptor_name":"Cell Size","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1023/a:1019861721160","doi":"https://doi.org/10.1023/a:1019861721160","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1019861721160","pdf_url":null,"source":{"id":"https://openalex.org/S33948212","display_name":"Cellular and Molecular Neurobiology","issn_l":"0272-4340","issn":["0272-4340","1573-6830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and Molecular Neurobiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11533743","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11533743","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Mol Neurobiol","raw_type":"Text"},{"id":"pmid:12363198","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12363198","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular and molecular neurobiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11533743","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11533743","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Mol Neurobiol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307534","display_name":"Autism Research Foundation","ror":"https://ror.org/00ssgfx80"},{"id":"https://openalex.org/F4320309636","display_name":"University of Minnesota","ror":"https://ror.org/03grvy078"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1528746151","https://openalex.org/W1975996377","https://openalex.org/W1994159682","https://openalex.org/W2099631476","https://openalex.org/W4245552230"],"related_works":["https://openalex.org/W1992581884","https://openalex.org/W1963898650","https://openalex.org/W2154672996","https://openalex.org/W2116964354","https://openalex.org/W2099631476","https://openalex.org/W2136932965","https://openalex.org/W2038679877","https://openalex.org/W2144696231","https://openalex.org/W7098653970","https://openalex.org/W4246242808"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":19},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":19},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":19},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}