{"id":"https://openalex.org/W94939561","doi":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","title":"Single Muscle Fiber Power Generation with Non\u2010Weightbearing Conditions: Does Muscle of Origin Play a Role?","display_name":"Single Muscle Fiber Power Generation with Non\u2010Weightbearing Conditions: Does Muscle of Origin Play a Role?","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W94939561","doi":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","mag":"94939561"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.27.1_supplement.lb711","doi":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050212596","display_name":"Jong\u2010Hee Kim","orcid":"https://orcid.org/0000-0002-1339-8156","observed_orcids":["https://orcid.org/0000-0002-1339-8156"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jong\u2010Hee Kim","raw_affiliation_strings":["Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006339128","display_name":"Windy S. Torgerud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Windy Torgerud","raw_affiliation_strings":["Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010129110","display_name":"Ted G. Graber","orcid":"https://orcid.org/0000-0002-5332-7838","observed_orcids":["https://orcid.org/0000-0002-5332-7838"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ted Graber","raw_affiliation_strings":["Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Haiming Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haiming Liu","raw_affiliation_strings":["Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088219712","display_name":"LaDora V. Thompson","orcid":"https://orcid.org/0000-0002-6481-9029","observed_orcids":["https://orcid.org/0000-0002-6481-9029"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"LaDora Thompson","raw_affiliation_strings":["Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Medicine and Rehabilitation University of Minnesota Minneapolis MN","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00622321,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.6259999871253967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.6259999871253967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.35420000553131104,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-weight-bearing","display_name":"non-weight bearing","score":0.7950000166893005},{"id":"https://openalex.org/keywords/hindlimb-unloading","display_name":"hindlimb unloading","score":0.9610000252723694},{"id":"https://openalex.org/keywords/myosin-heavy-chain-isoforms","display_name":"myosin heavy chain isoforms","score":0.9629999995231628},{"id":"https://openalex.org/keywords/fast-twitch-muscle","display_name":"fast-twitch muscle","score":0.6940000057220459},{"id":"https://openalex.org/keywords/type-i-muscle-fibres","display_name":"type I muscle fibers","score":0.9580000042915344},{"id":"https://openalex.org/keywords/soleus-muscle","display_name":"soleus muscle","score":0.8180000185966492},{"id":"https://openalex.org/keywords/plantaris","display_name":"plantaris","score":0.8339999914169312},{"id":"https://openalex.org/keywords/tibialis-anterior","display_name":"tibialis anterior","score":0.9990000128746033},{"id":"https://openalex.org/keywords/extensor-digitorum-longus","display_name":"extensor digitorum longus","score":1.0},{"id":"https://openalex.org/keywords/muscle-atrophy","display_name":"muscle atrophy","score":0.8769999742507935},{"id":"https://openalex.org/keywords/force-velocity-relationship","display_name":"force-velocity relationship","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.6113611459732056},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.559709370136261},{"id":"https://openalex.org/C2778640784","wikidata":"https://www.wikidata.org/wiki/Q168002","display_name":"Ankle","level":2,"score":0.5365016460418701},{"id":"https://openalex.org/C3017897630","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Muscle fibre","level":3,"score":0.4954768419265747},{"id":"https://openalex.org/C519885992","wikidata":"https://www.wikidata.org/wiki/Q161","display_name":"Fiber","level":2,"score":0.48584601283073425},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4825986623764038},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.2695056200027466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17022547125816345},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07080137729644775},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.27.1_supplement.lb711","doi":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.27.1_supplement.lb711","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2006416389","https://openalex.org/W1820918298","https://openalex.org/W2013861811","https://openalex.org/W1963527933","https://openalex.org/W2256760215","https://openalex.org/W2034583818","https://openalex.org/W2133255485","https://openalex.org/W2258082525","https://openalex.org/W2036135898","https://openalex.org/W121215751"],"abstract_inverted_index":{"The":[0,146,166],"purpose":[1],"of":[2,14,88,108,153,173,193,216],"this":[3],"study":[4],"was":[5,45,125],"to":[6,55,211],"examine":[7],"how":[8],"non\u2010weightbearing":[9],"(NWB)":[10],"alters":[11],"power":[12,80,135],"generation":[13],"myosin":[15],"heavy":[16],"chain":[17],"(MHC)":[18],"IIB,":[19],"IIXB,":[20],"and":[21,36,62,69,85,90,96,106,137,179],"IIX":[22],"fibers":[23,38,92,110,130,155,175,195,209],"from":[24,39,66,93,111,131,156,176,196],"the":[25,40,50,94,112,128,132,157,170,177,190,197,214],"plantaris":[26],"(PL),":[27],"tibialis":[28],"anterior":[29],"(TA),":[30],"extensor":[31],"digitorum":[32],"longus":[33],"(EDL)":[34],"muscles":[35],"MHCI":[37,154],"soleus":[41],"(SOL)":[42],"muscle.":[43],"NWB":[44,163],"achieved":[46],"in":[47,127],"rats":[48],"by":[49,74,117,164],"hindlimb":[51],"suspension":[52],"technique":[53],"(1":[54],"3":[56],"weeks).":[57],"Single":[58],"fiber":[59],"power,":[60],"force,":[61],"velocity":[63,86],"were":[64,72,114,159],"determined":[65],"force\u2010velocity":[67],"curves":[68],"MHC":[70,206],"isoforms":[71],"identified":[73],"SDS\u2010PAGE":[75],"(total":[76],"387":[77],"fibers).":[78],"Peak":[79],"(PP),":[81],"peak":[82],"force":[83,139],"(Po)":[84],"(Vmax)":[87],"MHCIIB":[89],"IIXB":[91],"TA":[95,178],"EDL":[97],"did":[98,141],"not":[99,142],"change":[100,143],"with":[101,119,144,162],"NWB.":[102,120,145,188],"In":[103],"contrast,":[104],"PP":[105],"Po":[107],"MHCII":[109,129,174,194],"PL":[113],"significantly":[115,160],"reduced":[116,161],"25\u201360%":[118],"Because":[121],"NWB\u2010induced":[122,203],"atrophy":[123],"(3\u201323%)":[124],"present":[126],"PL,":[133,198],"normalized":[134],"(NP)":[136],"specific":[138],"(SF)":[140],"contractile":[147,171,191],"parameters":[148],"(PP,":[149],"NP,":[150],"Po,":[151],"SF)":[152],"SOL":[158],"30\u201369%.":[165],"results":[167],"indicate":[168],"that":[169],"properties":[172,192],"EDL,":[180],"both":[181],"ankle":[182,200],"dorsiflexor":[183],"muscles,":[184],"are":[185,222],"maintained":[186],"during":[187],"However,":[189],"an":[199],"plantarflexor,":[201],"show":[202],"reductions.":[204],"Collectively,":[205],"type":[207],"II":[208],"adapt":[210],"NWB;":[212],"however,":[213],"extent":[215],"adaptation":[217],"is":[218],"muscle\u2010specific.":[219],"These":[220],"findings":[221],"important":[223],"when":[224],"designing":[225],"therapeutic":[226],"exercise":[227],"interventions.":[228]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}