{"id":"https://openalex.org/W94823826","doi":null,"title":"Prenatal diagnosis by amniocentesis and chorionic villus biopsy.","display_name":"Prenatal diagnosis by amniocentesis and chorionic villus biopsy.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W94823826","mag":"94823826","pmid":"https://pubmed.ncbi.nlm.nih.gov/21274247","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2327586"},"language":"en","primary_location":{"id":"pmid:21274247","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21274247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian family physician Medecin de famille canadien","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2327586/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035548100","display_name":"Reynolds Jl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"J L Reynolds","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5035548100"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00980244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":null,"first_page":"105","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13275","display_name":"Medical and Health Sciences Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3308","display_name":"Law"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13147","display_name":"Ethics and bioethics in healthcare","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-diagnosis","display_name":"prenatal diagnosis","score":1.0},{"id":"https://openalex.org/keywords/amniocentesis","display_name":"amniocentesis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chorionic-villus-sampling","display_name":"chorionic villus sampling","score":0.9950000047683716},{"id":"https://openalex.org/keywords/genetic-disorders","display_name":"genetic disorders","score":0.828000009059906},{"id":"https://openalex.org/keywords/genetic-counseling","display_name":"genetic counseling","score":0.5799999833106995},{"id":"https://openalex.org/keywords/general-practitioners","display_name":"general practitioners","score":0.5529999732971191},{"id":"https://openalex.org/keywords/ethics-of-abortion","display_name":"ethics of abortion","score":0.6589999794960022},{"id":"https://openalex.org/keywords/recombinant-dna-technology","display_name":"recombinant DNA technology","score":0.9169999957084656}],"concepts":[{"id":"https://openalex.org/C2777966818","wikidata":"https://www.wikidata.org/wiki/Q473768","display_name":"Amniocentesis","level":5,"score":0.9246065616607666},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.8402467966079712},{"id":"https://openalex.org/C2776555163","wikidata":"https://www.wikidata.org/wiki/Q1076497","display_name":"Chorionic villus sampling","level":5,"score":0.7796580791473389},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6487667560577393},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6091734170913696},{"id":"https://openalex.org/C2781385326","wikidata":"https://www.wikidata.org/wiki/Q2272222","display_name":"Chorionic villi","level":5,"score":0.5882981419563293},{"id":"https://openalex.org/C2778642596","wikidata":"https://www.wikidata.org/wiki/Q8452","display_name":"Abortion","level":3,"score":0.5764970183372498},{"id":"https://openalex.org/C80227256","wikidata":"https://www.wikidata.org/wiki/Q1124169","display_name":"Genetic counseling","level":2,"score":0.5700352191925049},{"id":"https://openalex.org/C3019714739","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"First trimester","level":4,"score":0.45403406023979187},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.45217517018318176},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.37478041648864746},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.297698438167572},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1316816806793213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08998820185661316}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:21274247","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21274247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian family physician Medecin de famille canadien","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2327586","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2327586/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Fam Physician","raw_type":"Text"},{"id":"mag:94823826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21274247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2327586","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2327586/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Fam Physician","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2073511627","https://openalex.org/W2980269208","https://openalex.org/W2421943259","https://openalex.org/W2889354062","https://openalex.org/W2586380561","https://openalex.org/W2992849762","https://openalex.org/W7099868218","https://openalex.org/W2045222714","https://openalex.org/W146372107","https://openalex.org/W2159649781"],"abstract_inverted_index":{"Prenatal":[0],"diagnosis":[1,56],"forms":[2],"only":[3,99,113],"a":[4,24],"small":[5],"part":[6],"of":[7,15,22,81,94,104],"day-to-day":[8],"family":[9],"practice,":[10],"but":[11,47],"the":[12,48,71,92,112],"techniques":[13],"are":[14,57],"critical":[16],"importance":[17],"to":[18,54,65,77,91,120],"couples":[19,78],"at":[20,79],"risk":[21,80],"having":[23],"child":[25],"affected":[26],"by":[27,37,102],"genetic":[28,109],"disorder.":[29],"Second":[30],"trimester":[31,39],"amniocentesis":[32],"will":[33],"probably":[34],"be":[35,100,121],"replaced":[36],"first":[38],"chorionic":[40],"villus":[41],"biopsy":[42],"and":[43,50,97],"recombinant":[44],"DNA":[45],"technology,":[46],"ethical":[49],"moral":[51],"problems":[52],"related":[53],"prenatal":[55,95,105],"not":[58],"so":[59],"easily":[60],"solved.":[61],"Family":[62],"physicians":[63],"need":[64],"examine":[66],"their":[67,126],"own":[68],"attitudes":[69],"toward":[70],"handicapped":[72,83],"before":[73],"they":[74],"offer":[75,117],"counselling":[76],"bearing":[82],"children.":[84],"The":[85],"controversy":[86],"over":[87],"abortion":[88],"is":[89,119],"central":[90],"issue":[93],"diagnosis,":[96],"may":[98],"resolved":[101],"development":[103],"treatments":[106],"for":[107],"certain":[108],"disorders.":[110],"Sometimes":[111],"thing":[114],"we":[115],"can":[116],"patients":[118],"with":[122],"them,":[123],"in":[124],"whatever":[125],"decisions":[127],"bring.":[128]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}