{"id":"https://openalex.org/W943153162","doi":null,"title":"Differences Between Oral and Skin Keratinocytes During Wound Healing","display_name":"Differences Between Oral and Skin Keratinocytes During Wound Healing","publication_year":2013,"publication_date":"2013-06-28","ids":{"openalex":"https://openalex.org/W943153162","mag":"943153162"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/10825346","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","pdf_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054492343","display_name":"Anna Turabelidze","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Anna Turabelidze","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5054492343"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-keratinocytes","display_name":"oral keratinocytes","score":0.796999990940094},{"id":"https://openalex.org/keywords/keratinocytes","display_name":"keratinocytes","score":0.9810000061988831},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.9549999833106995},{"id":"https://openalex.org/keywords/re-epithelialization","display_name":"re-epithelialization","score":0.9959999918937683},{"id":"https://openalex.org/keywords/keratinocyte-migration","display_name":"keratinocyte migration","score":0.9380000233650208},{"id":"https://openalex.org/keywords/keratinocyte-proliferation","display_name":"keratinocyte proliferation","score":0.8840000033378601},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9390000104904175},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.9350000023841858},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7580000162124634},{"id":"https://openalex.org/keywords/oral-mucosa","display_name":"oral mucosa","score":0.6499999761581421},{"id":"https://openalex.org/keywords/full-thickness-wounds","display_name":"full-thickness wounds","score":0.6140000224113464},{"id":"https://openalex.org/keywords/hypoxia-inducible-factor-1alpha","display_name":"hypoxia-inducible factor-1\u03b1","score":0.597000002861023},{"id":"https://openalex.org/keywords/hif-2alpha","display_name":"HIF-2\u03b1","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.8291757106781006},{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.7264509797096252},{"id":"https://openalex.org/C2779409057","wikidata":"https://www.wikidata.org/wiki/Q1776131","display_name":"Oral mucosa","level":2,"score":0.7150910496711731},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.6838544607162476},{"id":"https://openalex.org/C2779744641","wikidata":"https://www.wikidata.org/wiki/Q9614","display_name":"Tongue","level":2,"score":0.6086558103561401},{"id":"https://openalex.org/C2776193487","wikidata":"https://www.wikidata.org/wiki/Q32846","display_name":"Basement membrane","level":2,"score":0.5889995098114014},{"id":"https://openalex.org/C2776458125","wikidata":"https://www.wikidata.org/wiki/Q1827343","display_name":"Epidermis (zoology)","level":2,"score":0.528588056564331},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5231139063835144},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.5179871320724487},{"id":"https://openalex.org/C2777074287","wikidata":"https://www.wikidata.org/wiki/Q1473931","display_name":"Keratinocyte","level":3,"score":0.4925175607204437},{"id":"https://openalex.org/C2777624698","wikidata":"https://www.wikidata.org/wiki/Q505531","display_name":"Dermis","level":2,"score":0.4881749749183655},{"id":"https://openalex.org/C190567982","wikidata":"https://www.wikidata.org/wiki/Q7535422","display_name":"Skin repair","level":3,"score":0.45397496223449707},{"id":"https://openalex.org/C2779636128","wikidata":"https://www.wikidata.org/wiki/Q1978278","display_name":"Stratified squamous epithelium","level":3,"score":0.4505288898944855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44620105624198914},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.35131412744522095},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33126211166381836},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.14180967211723328},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.07631033658981323},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:figshare.com:article/10825346","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","pdf_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:943153162","doi":null,"is_oa":false,"landing_page_url":"https://indigo.uic.edu/articles/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:figshare.com:article/10825346","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","pdf_url":"https://figshare.com/articles/thesis/Differences_Between_Oral_and_Skin_Keratinocytes_During_Wound_Healing/10825346","source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W943153162.pdf","grobid_xml":"https://content.openalex.org/works/W943153162.grobid-xml"},"referenced_works_count":211,"referenced_works":["https://openalex.org/W98461984","https://openalex.org/W205789206","https://openalex.org/W206843295","https://openalex.org/W208081447","https://openalex.org/W1481988255","https://openalex.org/W1487581481","https://openalex.org/W1488482313","https://openalex.org/W1504954000","https://openalex.org/W1527514943","https://openalex.org/W1571209082","https://openalex.org/W1572867882","https://openalex.org/W1574135181","https://openalex.org/W1577577364","https://openalex.org/W1872370876","https://openalex.org/W1886866587","https://openalex.org/W1894380633","https://openalex.org/W1902236642","https://openalex.org/W1923917571","https://openalex.org/W1949832432","https://openalex.org/W1965274097","https://openalex.org/W1965434649","https://openalex.org/W1967058955","https://openalex.org/W1967087287","https://openalex.org/W1967802597","https://openalex.org/W1968084778","https://openalex.org/W1969124103","https://openalex.org/W1970516412","https://openalex.org/W1970794616","https://openalex.org/W1971248512","https://openalex.org/W1971634317","https://openalex.org/W1974113351","https://openalex.org/W1975392093","https://openalex.org/W1976068877","https://openalex.org/W1976155616","https://openalex.org/W1976794059","https://openalex.org/W1977631233","https://openalex.org/W1978235146","https://openalex.org/W1980035932","https://openalex.org/W1980398407","https://openalex.org/W1983424467","https://openalex.org/W1984002529","https://openalex.org/W1984821767","https://openalex.org/W1986080495","https://openalex.org/W1986097125","https://openalex.org/W1986308133","https://openalex.org/W1987383089","https://openalex.org/W1988683816","https://openalex.org/W1989021197","https://openalex.org/W1990669035","https://openalex.org/W1991272056","https://openalex.org/W1991671544","https://openalex.org/W1992153055","https://openalex.org/W1994387286","https://openalex.org/W1994435662","https://openalex.org/W1995438382","https://openalex.org/W1996108441","https://openalex.org/W1996994627","https://openalex.org/W1998699021","https://openalex.org/W1999835001","https://openalex.org/W2000292756","https://openalex.org/W2000566788","https://openalex.org/W2002633784","https://openalex.org/W2004386707","https://openalex.org/W2005784214","https://openalex.org/W2006120701","https://openalex.org/W2008052120","https://openalex.org/W2009414873","https://openalex.org/W2010051632","https://openalex.org/W2010717111","https://openalex.org/W2012030587","https://openalex.org/W2013214195","https://openalex.org/W2013987164","https://openalex.org/W2015031004","https://openalex.org/W2015050967","https://openalex.org/W2016484384","https://openalex.org/W2017775470","https://openalex.org/W2018204790","https://openalex.org/W2018243568","https://openalex.org/W2021861225","https://openalex.org/W2022380333","https://openalex.org/W2022467685","https://openalex.org/W2023030375","https://openalex.org/W2024580059","https://openalex.org/W2025032647","https://openalex.org/W2025497355","https://openalex.org/W2025799038","https://openalex.org/W2026028109","https://openalex.org/W2026803058","https://openalex.org/W2027150670","https://openalex.org/W2028543411","https://openalex.org/W2028627749","https://openalex.org/W2029227350","https://openalex.org/W2030281917","https://openalex.org/W2031809949","https://openalex.org/W2033620247","https://openalex.org/W2035185167","https://openalex.org/W2037585411","https://openalex.org/W2038818854","https://openalex.org/W2041235830","https://openalex.org/W2042202567","https://openalex.org/W2042289154","https://openalex.org/W2043332074","https://openalex.org/W2044538506","https://openalex.org/W2045243608","https://openalex.org/W2046700952","https://openalex.org/W2051038913","https://openalex.org/W2051574211","https://openalex.org/W2053343398","https://openalex.org/W2053404797","https://openalex.org/W2053800469","https://openalex.org/W2054012934","https://openalex.org/W2056819482","https://openalex.org/W2058703459","https://openalex.org/W2060100763","https://openalex.org/W2060847230","https://openalex.org/W2061329089","https://openalex.org/W2061559414","https://openalex.org/W2062025417","https://openalex.org/W2062199188","https://openalex.org/W2062352917","https://openalex.org/W2062877496","https://openalex.org/W2063220206","https://openalex.org/W2063339950","https://openalex.org/W2063700930","https://openalex.org/W2069837802","https://openalex.org/W2070167505","https://openalex.org/W2070402163","https://openalex.org/W2072640657","https://openalex.org/W2073292917","https://openalex.org/W2073450907","https://openalex.org/W2073505035","https://openalex.org/W2073917514","https://openalex.org/W2075853586","https://openalex.org/W2078009668","https://openalex.org/W2080964493","https://openalex.org/W2083170353","https://openalex.org/W2084458279","https://openalex.org/W2085600594","https://openalex.org/W2086491289","https://openalex.org/W2086696946","https://openalex.org/W2087239912","https://openalex.org/W2087272945","https://openalex.org/W2087904891","https://openalex.org/W2089173686","https://openalex.org/W2090026276","https://openalex.org/W2091094644","https://openalex.org/W2091664620","https://openalex.org/W2092084302","https://openalex.org/W2092716316","https://openalex.org/W2093301599","https://openalex.org/W2093985540","https://openalex.org/W2096813909","https://openalex.org/W2096852597","https://openalex.org/W2098510154","https://openalex.org/W2098676863","https://openalex.org/W2100742787","https://openalex.org/W2105652693","https://openalex.org/W2106059813","https://openalex.org/W2111002265","https://openalex.org/W2112006376","https://openalex.org/W2115465396","https://openalex.org/W2118654016","https://openalex.org/W2120102597","https://openalex.org/W2121073499","https://openalex.org/W2123550509","https://openalex.org/W2125366323","https://openalex.org/W2126091128","https://openalex.org/W2127938351","https://openalex.org/W2128443399","https://openalex.org/W2130074505","https://openalex.org/W2130793261","https://openalex.org/W2131986778","https://openalex.org/W2131987407","https://openalex.org/W2132670907","https://openalex.org/W2133284260","https://openalex.org/W2137178267","https://openalex.org/W2138354687","https://openalex.org/W2138642580","https://openalex.org/W2139786796","https://openalex.org/W2140273413","https://openalex.org/W2141366082","https://openalex.org/W2141880708","https://openalex.org/W2145040122","https://openalex.org/W2145858633","https://openalex.org/W2147372943","https://openalex.org/W2147689435","https://openalex.org/W2148927308","https://openalex.org/W2153149551","https://openalex.org/W2156234950","https://openalex.org/W2158902083","https://openalex.org/W2159193579","https://openalex.org/W2159489508","https://openalex.org/W2160085982","https://openalex.org/W2161682775","https://openalex.org/W2162303920","https://openalex.org/W2162338634","https://openalex.org/W2165399241","https://openalex.org/W2167928913","https://openalex.org/W2171118123","https://openalex.org/W2171282651","https://openalex.org/W2183019695","https://openalex.org/W2184860549","https://openalex.org/W2186509953","https://openalex.org/W2210990792","https://openalex.org/W2244958898","https://openalex.org/W2317364560","https://openalex.org/W2325727928","https://openalex.org/W2411727611","https://openalex.org/W2413791853","https://openalex.org/W2421597951","https://openalex.org/W2582112616"],"related_works":["https://openalex.org/W2133866074","https://openalex.org/W2052591431","https://openalex.org/W4293585624","https://openalex.org/W2342504605","https://openalex.org/W2026028109","https://openalex.org/W2085600594","https://openalex.org/W3190921687","https://openalex.org/W2063521119","https://openalex.org/W4290791577","https://openalex.org/W2064219573"],"abstract_inverted_index":{"Epithelial":[0],"cells":[1,132,157,409],"provide":[2],"barrier":[3],"protection":[4],"throughout":[5],"the":[6,27,44,48,59,67,83,86,98,125,142,149,154,160,206,212,237,249,276,290,311,317,329,368,414],"body.":[7],"Although":[8],"oral":[9,45,68,99,214,253,280,299,337,360,372],"mucosal":[10,32,69,383],"and":[11,61,81,89,145,166,169,182,209,319,332,338,356,385],"skin":[12,38,49,208,339],"epithelium":[13,60,65],"share":[14],"many":[15,51],"morphological":[16],"similarities":[17],"they":[18],"also":[19],"exhibit":[20],"distinct":[21],"capacities.\\nOne":[22],"significant":[23],"functional":[24],"difference":[25],"is":[26,54,101,119,122,187,255,264,282,306,374],"wound":[28,117,134,161,191,318],"healing":[29,118],"response,":[30],"as":[31,174,391],"wounds":[33,201,230],"heal":[34],"more":[35],"rapidly":[36],"than":[37,233,257,358],"(Szpaderska":[39,362],"2005).":[40,363],"The":[41,64],"structure":[42],"of":[43,56,66,85,116,124,177,185,211,252,259,268,279,314,328,352,382,398],"mucosa":[46,100,215,300,373],"resembles":[47],"in":[50,97,270,284,298,316,323,335,371,407],"ways.":[52],"It":[53],"composed":[55],"two":[57],"layers,":[58],"connective":[62,151],"tissue.":[63,152],"membrane":[70,144],"may":[71],"be":[72,302,377],"keratinized":[73,93],"or":[74,395],"nonkeratinized":[75],"depending":[76],"on":[77,204],"location.":[78],"In":[79,153,227],"humans":[80],"mice,":[82],"dorsum":[84],"tongue,":[87],"gingiva":[88],"hard":[90],"palate":[91],"are":[92,202,231,310],"tissues.":[94],"Keratinized":[95],"tissue":[96,384],"very":[102,218],"similar":[103],"to":[104,111,286,288,325,345,376,379,387,402,413,417],"skin,":[105],"making":[106],"it":[107],"a":[108,164,175,193],"good":[109],"model":[110],"study":[112,194,272,400],"healing.\\nOne":[113],"important":[114],"aspect":[115,267],"re-epithelialization,":[120,269],"which":[121],"restoration":[123],"epidermis":[126],"by":[127],"keratinocytes.":[128,261],"Upon":[129],"injury,":[130],"epithelial":[131,408],"from":[133,141],"edges":[135],"dissolve":[136],"their":[137],"hemidesmosomal":[138],"connections,":[139],"detach":[140],"basement":[143],"move":[146],"quickly":[147],"across":[148],"exposed":[150],"normal":[155],"situation,":[156],"just":[158],"behind":[159],"edge":[162],"undergo":[163],"proliferative":[165,181,250],"migratory":[167,183,277],"burst":[168],"effectively":[170],"replace":[171],"keratinocytes":[172,186,254,281,309,340,348,361],"lost":[173],"result":[176],"injury.":[178,418],"This":[179],"tremendous":[180],"capacity":[184,251,278],"critical":[188,266],"for":[189,295],"effective":[190],"re-epithelialization.\\nIn":[192],"where":[195],"equivalent":[196],"full":[197],"thickness":[198],"1mm":[199],"diameter":[200],"created":[203],"both":[205,353],"dorsal":[207],"tongue":[210],"mouse,":[213],"wounds\\nix\\nexhibit":[216],"re-epithelialization":[217],"rapidly,":[219],"with":[220],"100%":[221],"completion":[222],"at":[223,236],"24":[224,238],"hours":[225],"post-injury.":[226],"contrast,":[228],"cutaneous":[229],"less":[232],"25%":[234],"re-epithelialized":[235],"hour":[239],"time":[240],"point":[241],"(Schrementi":[242],"2008).":[243],"These":[244,364],"data":[245],"strongly":[246],"suggest":[247],"that":[248,258,292,367,410],"greater":[256],"dermal":[260],"As":[262],"migration":[263],"another":[265],"this":[271,399],"we":[273],"investigate":[274],"whether":[275],"different":[283],"comparison":[285],"skin.\\nEvidence":[287],"support":[289],"hypothesis":[291],"differences":[293,406],"responsible":[294],"rapid":[296],"repair":[297,370],"could":[301],"intrinsic":[303,380],"keratinocyte":[304],"characteristics":[305,381],"available.":[307],"Since":[308],"major":[312],"source":[313],"VEGF":[315,330,354],"produce":[320],"pro-angiogenic":[321],"factors":[322,389],"response":[324,416],"hypoxia,":[326,346],"investigation":[327],"mRNA":[331,357],"protein":[333,355],"levels":[334,351],"isolated":[336],"was":[341,401],"conducted.":[342],"When":[343],"subjected":[344],"epidermal":[347],"produced":[349],"higher":[350],"did":[359],"findings":[365],"imply":[366],"superior":[369],"likely":[375],"related":[378],"not":[386],"environmental":[388],"such":[390],"temperature,":[392],"salivary":[393],"flow":[394],"microflora.\\nThe":[396],"goal":[397],"identify":[403],"innate":[404],"positional":[405],"might":[411],"contribute":[412],"site-specific":[415]},"counts_by_year":[],"updated_date":"2026-09-16T18:09:00.828671","created_date":"2016-06-24T00:00:00"}