{"id":"https://openalex.org/W93747925","doi":"https://doi.org/10.3920/978-90-8686-776-9_43","title":"Identification BMECs receptors interacting with Trypanosoma brucei brucei","display_name":"Identification BMECs receptors interacting with Trypanosoma brucei brucei","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W93747925","doi":"https://doi.org/10.3920/978-90-8686-776-9_43","mag":"93747925"},"language":"en","primary_location":{"id":"doi:10.3920/978-90-8686-776-9_43","doi":"https://doi.org/10.3920/978-90-8686-776-9_43","is_oa":false,"landing_page_url":"https://doi.org/10.3920/978-90-8686-776-9_43","pdf_url":null,"source":{"id":"https://openalex.org/S4306464271","display_name":"Wageningen Academic Publishers eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Farm animal proteomics 2013","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4246135517","display_name":"Farm animal proteomics 2013"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003811855","display_name":"Miroslava Vincova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3132579651","display_name":"University of Veterinary Medicine in Ko\u0161ice","ror":"https://ror.org/05btaka91","country_code":"SK","type":"education","lineage":["https://openalex.org/I3132579651"]}],"countries":["SK"],"is_corresponding":true,"raw_author_name":"Miroslava Vincova","raw_affiliation_strings":["Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","University of veterinary medicine and pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","institution_ids":["https://openalex.org/I3132579651"]},{"raw_affiliation_string":"University of veterinary medicine and pharmacy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072459478","display_name":"Andrej Kov\u00e1\u010d","orcid":"https://orcid.org/0000-0002-3223-8705","observed_orcids":["https://orcid.org/0000-0002-3223-8705"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210145572","display_name":"Institute of Neuroimmunology of the Slovak Academy of Sciences","ror":"https://ror.org/05c516317","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Andrej Kovac","raw_affiliation_strings":["Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","Slovak Academy of Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]},{"raw_affiliation_string":"Slovak Academy of Sciences","institution_ids":["https://openalex.org/I207624831"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003336976","display_name":"Lucia Pulzov\u00e1","orcid":"https://orcid.org/0000-0002-1691-366X","observed_orcids":["https://orcid.org/0000-0002-1691-366X"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I3132579651","display_name":"University of Veterinary Medicine in Ko\u0161ice","ror":"https://ror.org/05btaka91","country_code":"SK","type":"education","lineage":["https://openalex.org/I3132579651"]},{"id":"https://openalex.org/I4210136554","display_name":"University of Veterinary Medicine","ror":"https://ror.org/03vayv672","country_code":"HU","type":"education","lineage":["https://openalex.org/I4210136554"]},{"id":"https://openalex.org/I4210145572","display_name":"Institute of Neuroimmunology of the Slovak Academy of Sciences","ror":"https://ror.org/05c516317","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]}],"countries":["HU","SK"],"is_corresponding":false,"raw_author_name":"Lucia Pulzova","raw_affiliation_strings":["Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","Slovak Academy of Sciences","University of Veterinary Medicine and Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]},{"raw_affiliation_string":"Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","institution_ids":["https://openalex.org/I3132579651"]},{"raw_affiliation_string":"Slovak Academy of Sciences","institution_ids":["https://openalex.org/I207624831"]},{"raw_affiliation_string":"University of Veterinary Medicine and Pharmacy","institution_ids":["https://openalex.org/I4210136554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113797104","display_name":"Saskia Dolinsk\u00e1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3132579651","display_name":"University of Veterinary Medicine in Ko\u0161ice","ror":"https://ror.org/05btaka91","country_code":"SK","type":"education","lineage":["https://openalex.org/I3132579651"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Saskia Dolinska","raw_affiliation_strings":["Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","University of veterinary medicine and pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","institution_ids":["https://openalex.org/I3132579651"]},{"raw_affiliation_string":"University of veterinary medicine and pharmacy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086153199","display_name":"Mangesh Ramesh Bhide","orcid":"https://orcid.org/0000-0001-8734-4364","observed_orcids":["https://orcid.org/0000-0001-8734-4364"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I3132579651","display_name":"University of Veterinary Medicine in Ko\u0161ice","ror":"https://ror.org/05btaka91","country_code":"SK","type":"education","lineage":["https://openalex.org/I3132579651"]},{"id":"https://openalex.org/I4210136554","display_name":"University of Veterinary Medicine","ror":"https://ror.org/03vayv672","country_code":"HU","type":"education","lineage":["https://openalex.org/I4210136554"]},{"id":"https://openalex.org/I4210145572","display_name":"Institute of Neuroimmunology of the Slovak Academy of Sciences","ror":"https://ror.org/05c516317","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]}],"countries":["HU","SK"],"is_corresponding":false,"raw_author_name":"Mangesh R. Bhide","raw_affiliation_strings":["Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","Slovak Academy of Sciences","University of Veterinary Medicine and Pharmacy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210145572"]},{"raw_affiliation_string":"Laboratory of Biomedical Microbiology and Immunology, Department of microbiology and immunology, University of Veterinary Medicine and Pharmacy, Kosice, Slovakia","institution_ids":["https://openalex.org/I3132579651"]},{"raw_affiliation_string":"Slovak Academy of Sciences","institution_ids":["https://openalex.org/I207624831"]},{"raw_affiliation_string":"University of Veterinary Medicine and Pharmacy","institution_ids":["https://openalex.org/I4210136554"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5003811855"],"corresponding_institution_ids":["https://openalex.org/I3132579651"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04586534,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"163","last_page":"166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.03480000048875809,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trypanosoma-brucei-brucei","display_name":"Trypanosoma brucei brucei","score":0.9610000252723694},{"id":"https://openalex.org/keywords/brain-microvascular-endothelial-cells","display_name":"brain microvascular endothelial cells","score":0.9620000123977661},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.6940000057220459},{"id":"https://openalex.org/keywords/ligand-receptor-interactions","display_name":"ligand-receptor interactions","score":0.8880000114440918},{"id":"https://openalex.org/keywords/neuroinvasion","display_name":"neuroinvasion","score":0.7630000114440918},{"id":"https://openalex.org/keywords/trypanosomiasis","display_name":"trypanosomiasis","score":0.7760000228881836},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.699999988079071},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.8799999952316284}],"concepts":[{"id":"https://openalex.org/C2779502636","wikidata":"https://www.wikidata.org/wiki/Q33244","display_name":"Trypanosoma brucei","level":3,"score":0.9752938151359558},{"id":"https://openalex.org/C2778792689","wikidata":"https://www.wikidata.org/wiki/Q203133","display_name":"African trypanosomiasis","level":3,"score":0.6969609260559082},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6902602314949036},{"id":"https://openalex.org/C2779549974","wikidata":"https://www.wikidata.org/wiki/Q541987","display_name":"Trypanosoma","level":2,"score":0.5203016400337219},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5021231174468994},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.4763094186782837},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.454540491104126},{"id":"https://openalex.org/C2909346784","wikidata":"https://www.wikidata.org/wiki/Q33244","display_name":"Trypanosoma brucei rhodesiense","level":4,"score":0.4413875341415405},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.44132357835769653},{"id":"https://openalex.org/C2778143080","wikidata":"https://www.wikidata.org/wiki/Q2443552","display_name":"Trypanosomiasis","level":2,"score":0.3882037103176117},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2484654188156128},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19170141220092773},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.12973850965499878},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09516239166259766},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3920/978-90-8686-776-9_43","doi":"https://doi.org/10.3920/978-90-8686-776-9_43","is_oa":false,"landing_page_url":"https://doi.org/10.3920/978-90-8686-776-9_43","pdf_url":null,"source":{"id":"https://openalex.org/S4306464271","display_name":"Wageningen Academic Publishers eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Farm animal proteomics 2013","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1981971321","https://openalex.org/W1984431363","https://openalex.org/W2034995612","https://openalex.org/W2037492031","https://openalex.org/W2038428454","https://openalex.org/W2083034526","https://openalex.org/W2164491927"],"related_works":["https://openalex.org/W2561092291","https://openalex.org/W2134248390","https://openalex.org/W2016154498","https://openalex.org/W18445103","https://openalex.org/W2151627275","https://openalex.org/W214733707","https://openalex.org/W4254860060","https://openalex.org/W2042549084","https://openalex.org/W2034995612","https://openalex.org/W3199700521"],"abstract_inverted_index":{"Neural":[0],"Trypanosomiasis":[1],"is":[2,67,187],"fatal":[3],"disease":[4],"caused":[5],"by":[6,30,122],"Trypanosoma":[7,184],"brucei.":[8],"T.":[9,18,21,24,72],"brucei":[10,19,22,25,73],"complex":[11],"consists":[12],"of":[13,33,38,93,108,115,175,183],"three":[14],"major":[15],"subspecies":[16],"namely":[17],"brucei,":[20],"gambiense,":[23],"rhodesiense.":[26],"They":[27],"are":[28,45],"transmitted":[29],"the":[31,34,49,58,83,125,148,165,172],"saliva":[32],"infected":[35],"tsetse":[36],"flies":[37],"genus":[39],"Glossina":[40],"during":[41,168,181],"blood":[42,50,84],"meal.":[43],"Trypanosomas":[44],"extracellular,":[46],"spread":[47],"through":[48,185],"stream":[51],"to":[52,69,81,97,99,117,136,152,189],"various":[53],"niches,":[54],"and":[55],"consequently":[56],"invade":[57],"central":[59],"nervous":[60],"system":[61],"(Masocha":[62],"et":[63,142],"al.,":[64],"2007).":[65],"It":[66],"necessary":[68],"know":[70],"how":[71],"interacts":[74],"with":[75],"brain":[76,85],"microvascular":[77],"endothelial":[78],"cells":[79],"(BMECs)":[80],"cross":[82,137],"barrier.":[86],"Previous":[87],"studies":[88],"have":[89,96],"shown":[90],"that":[91,160],"majority":[92],"extracellular":[94,126],"pathogens":[95],"adhere":[98],"BMEC":[100],"first":[101],"(transient":[102],"adhesion),":[103,120],"which":[104,178],"then":[105],"induces":[106],"series":[107],"cell":[109],"events":[110],"causing":[111],"more":[112,132],"firm":[113],"adhesion":[114,156],"pathogen":[116,135],"BMECs":[118,159],"(stationary":[119],"followed":[121],"alteration":[123],"in":[124,140,164],"matrix":[127],"near":[128],"tight":[129],"junctions":[130],"allowing":[131],"space":[133],"for":[134],"BBB":[138,186],"(reviewed":[139],"Bencurova":[141],"al.":[143],"2011).":[144],"To":[145],"this":[146],"background,":[147],"study":[149],"was":[150],"aimed":[151],"identify":[153],"putative":[154],"surface":[155],"receptors":[157],"on":[158],"may":[161],"take":[162,179],"part":[163],"Trypanosoma:BMEC":[166],"interface":[167],"transient":[169],"adhesion.":[170],"Unfolding":[171],"underlying":[173],"principles":[174],"ligand:receptor":[176],"interactions,":[177],"place":[180],"passage":[182],"important":[188],"understand":[190],"its":[191],"neuroinvasive":[192],"mechanisms.":[193]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}