{"id":"https://openalex.org/W9330873","doi":null,"title":"Imaging schizophrenia: data fusion approaches to characterize and classify","display_name":"Imaging schizophrenia: data fusion approaches to characterize and classify","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W9330873","mag":"9330873"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.rit.edu:theses-5554","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.rit.edu/theses/4550","pdf_url":"https://scholarworks.rit.edu/theses/4550","source":{"id":"https://openalex.org/S4306402456","display_name":"RIT Scholar Works (Rochester Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155173764","host_organization_name":"Rochester Institute of Technology","host_organization_lineage":["https://openalex.org/I155173764"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses","raw_type":"text"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.rit.edu/theses/4550","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016698254","display_name":"Andrew M. Michael","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andrew M. Michael","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5016698254"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.7006999850273132,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.7006999850273132,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.24979999661445618,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":1.0},{"id":"https://openalex.org/keywords/multimodal-fusion","display_name":"multimodal fusion","score":0.8669999837875366},{"id":"https://openalex.org/keywords/structural-mri","display_name":"structural MRI","score":0.8920000195503235},{"id":"https://openalex.org/keywords/fmri","display_name":"functional MRI","score":0.9819999933242798},{"id":"https://openalex.org/keywords/diffusion-tensor-imaging","display_name":"diffusion tensor imaging","score":0.9990000128746033},{"id":"https://openalex.org/keywords/canonical-correlation-analysis","display_name":"canonical correlation analysis","score":0.8809999823570251},{"id":"https://openalex.org/keywords/cross-correlation-function","display_name":"cross correlation function","score":0.6579999923706055},{"id":"https://openalex.org/keywords/symptom-scores","display_name":"symptom scores","score":0.515999972820282},{"id":"https://openalex.org/keywords/disconnection-hypothesis","display_name":"disconnection hypothesis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/cognitive-dysmetria","display_name":"cognitive dysmetria","score":0.9490000009536743},{"id":"https://openalex.org/keywords/superior-longitudinal-fasciculus","display_name":"superior longitudinal fasciculus","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.8339999914169312},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":1.0},{"id":"https://openalex.org/keywords/sensorimotor-tasks","display_name":"sensorimotor tasks","score":0.9150000214576721},{"id":"https://openalex.org/keywords/brain-classification","display_name":"brain classification","score":0.6359999775886536},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"neuroimaging","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C33954974","wikidata":"https://www.wikidata.org/wiki/Q486494","display_name":"Sensor fusion","level":2,"score":0.5668347477912903},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5537857413291931},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.49634677171707153},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4934164583683014},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4203539490699768},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32558298110961914},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:scholarworks.rit.edu:theses-5554","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.rit.edu/theses/4550","pdf_url":"https://scholarworks.rit.edu/theses/4550","source":{"id":"https://openalex.org/S4306402456","display_name":"RIT Scholar Works (Rochester Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155173764","host_organization_name":"Rochester Institute of Technology","host_organization_lineage":["https://openalex.org/I155173764"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses","raw_type":"text"},{"id":"pmh:oai:repository.rit.edu:theses-5554","doi":null,"is_oa":false,"landing_page_url":"https://repository.rit.edu/theses/4550","pdf_url":null,"source":{"id":"https://openalex.org/S4306402456","display_name":"RIT Scholar Works (Rochester Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155173764","host_organization_name":"Rochester Institute of Technology","host_organization_lineage":["https://openalex.org/I155173764"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses","raw_type":"text"},{"id":"mag:9330873","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.rit.edu/cgi/viewcontent.cgi?article=5554&context=theses","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.rit.edu:theses-5554","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.rit.edu/theses/4550","pdf_url":"https://scholarworks.rit.edu/theses/4550","source":{"id":"https://openalex.org/S4306402456","display_name":"RIT Scholar Works (Rochester Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155173764","host_organization_name":"Rochester Institute of Technology","host_organization_lineage":["https://openalex.org/I155173764"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theses","raw_type":"text"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W9330873.pdf","grobid_xml":"https://content.openalex.org/works/W9330873.grobid-xml"},"referenced_works_count":102,"referenced_works":["https://openalex.org/W1509285273","https://openalex.org/W1560724230","https://openalex.org/W1601835124","https://openalex.org/W1617570115","https://openalex.org/W1757694062","https://openalex.org/W1903033156","https://openalex.org/W1923168292","https://openalex.org/W1968870951","https://openalex.org/W1973871544","https://openalex.org/W1975427503","https://openalex.org/W1977421564","https://openalex.org/W1979773754","https://openalex.org/W1982142654","https://openalex.org/W1983695475","https://openalex.org/W1985327120","https://openalex.org/W1987498894","https://openalex.org/W1990577595","https://openalex.org/W1993616139","https://openalex.org/W1995362640","https://openalex.org/W1997677703","https://openalex.org/W1999514770","https://openalex.org/W1999887912","https://openalex.org/W1999992635","https://openalex.org/W2003288100","https://openalex.org/W2005726303","https://openalex.org/W2006883575","https://openalex.org/W2008016994","https://openalex.org/W2009077748","https://openalex.org/W2009580422","https://openalex.org/W2014693279","https://openalex.org/W2015393217","https://openalex.org/W2019410645","https://openalex.org/W2020789214","https://openalex.org/W2022496892","https://openalex.org/W2025274737","https://openalex.org/W2034089470","https://openalex.org/W2038381254","https://openalex.org/W2040709265","https://openalex.org/W2041042823","https://openalex.org/W2044004318","https://openalex.org/W2044829843","https://openalex.org/W2050626277","https://openalex.org/W2051203581","https://openalex.org/W2052644075","https://openalex.org/W2053717239","https://openalex.org/W2053742943","https://openalex.org/W2058034465","https://openalex.org/W2058046532","https://openalex.org/W2058492979","https://openalex.org/W2059752408","https://openalex.org/W2060012280","https://openalex.org/W2060899536","https://openalex.org/W2063237661","https://openalex.org/W2070287713","https://openalex.org/W2072486526","https://openalex.org/W2075578206","https://openalex.org/W2079937681","https://openalex.org/W2082094264","https://openalex.org/W2089488771","https://openalex.org/W2089868642","https://openalex.org/W2096052879","https://openalex.org/W2099159042","https://openalex.org/W2099626510","https://openalex.org/W2100235303","https://openalex.org/W2106654511","https://openalex.org/W2108646822","https://openalex.org/W2109187468","https://openalex.org/W2115428913","https://openalex.org/W2117663940","https://openalex.org/W2118421222","https://openalex.org/W2119848633","https://openalex.org/W2121678235","https://openalex.org/W2124529404","https://openalex.org/W2125277802","https://openalex.org/W2126159475","https://openalex.org/W2133215332","https://openalex.org/W2136763679","https://openalex.org/W2137231705","https://openalex.org/W2140343355","https://openalex.org/W2140606211","https://openalex.org/W2143785313","https://openalex.org/W2147655416","https://openalex.org/W2148601705","https://openalex.org/W2148828979","https://openalex.org/W2150174494","https://openalex.org/W2150667092","https://openalex.org/W2152380584","https://openalex.org/W2152644750","https://openalex.org/W2153525031","https://openalex.org/W2157752823","https://openalex.org/W2164255527","https://openalex.org/W2165152940","https://openalex.org/W2168251919","https://openalex.org/W2170644672","https://openalex.org/W2170916601","https://openalex.org/W2331797066","https://openalex.org/W2413084273","https://openalex.org/W2421603745","https://openalex.org/W2472388925","https://openalex.org/W2480728306","https://openalex.org/W2799061466","https://openalex.org/W3146425672"],"related_works":["https://openalex.org/W2790691033","https://openalex.org/W3159849182","https://openalex.org/W2931719897","https://openalex.org/W7140222405","https://openalex.org/W2125277802","https://openalex.org/W2137911531","https://openalex.org/W4393750606","https://openalex.org/W2767785333","https://openalex.org/W2097167879","https://openalex.org/W2128042129"],"abstract_inverted_index":{"Schizophrenia":[0],"is":[1,168,187,282],"a":[2,169,191,279],"complex,":[3],"chronic":[4],"and":[5,24,49,61,78,87,98,127,161,173,225,274,293,299,340,382,394,401],"disabling":[6],"mental":[7],"disorder":[8],"that":[9,268,320,350],"affects":[10],"about":[11,69],"one":[12],"percent":[13],"of":[14,20,73,82,113,124,130,142,213,240,314,338,343],"the":[15,70,80,84,88,111,131,136,203,269,297,300,335,341,353,370],"adult":[16],"population.":[17],"The":[18,166,217,250,264,310,331,373,389],"etiology":[19],"schizophrenia":[21,96,214,339],"remains":[22],"elusive":[23],"to":[25,33,45,66,107,138,152,189,208,223,236,243,261,305,323,385,399,406],"date":[26],"there":[27],"are":[28,91,102,215,220,259,303,392],"no":[29],"image":[30],"based":[31],"tools":[32],"diagnose":[34],"it.":[35],"Advancements":[36],"in":[37,50,284,287,296,308,352,369,376],"magnetic":[38],"resonance":[39],"imaging":[40,64],"(MRI)":[41],"have":[42,357],"enabled":[43],"researchers":[44],"develop":[46,150],"less":[47,326],"invasive":[48],"vivo":[51],"techniques,":[52],"such":[53],"as":[54],"structural":[55,294],"MRI":[56,59],"(sMRI),":[57],"functional":[58,85,178,275,291],"(fMRI)":[60],"diffusion":[62],"tensor":[63],"(DTI),":[65],"construct":[67],"theories":[68],"neural":[71],"underpinnings":[72],"schizophrenia.":[74,388],"With":[75],"sMRI,":[76],"fMRI":[77,157,160,317],"DTI":[79,162],"distribution":[81],"tissues,":[83],"activity":[86,179,276,292],"brain":[89,167,199,241,245,404,408],"network":[90],"imaged":[92],"respectively.":[93],"Subjects":[94],"with":[95,104,155,158,163,247],"(SZ)":[97],"healthy":[99,400],"controls":[100],"(HC)":[101],"scanned":[103],"different":[105,316,324],"modalities":[106,196],"identify":[108],"differences,":[109],"but":[110],"analysis":[112,129,194,234],"each":[114],"modality":[115],"has":[116],"traditionally":[117],"been":[118],"carried":[119],"out":[120],"separately.":[121],"Data":[122],"fusion":[123,257,266,313,348],"multimodal":[125],"data":[126,242,405],"an":[128],"joint":[132],"information":[133],"may":[134],"hold":[135],"key":[137],"reveal":[139,379],"hidden":[140],"traces":[141],"this":[143,147,377],"subtle":[144],"disorder.":[145],"In":[146,227],"work":[148,378],"we":[149,230],"techniques":[151],"correlate":[153],"sMRI":[154],"fMRI,":[156],"other":[159,402],"symptom":[164],"scores.":[165],"highly":[170],"interconnected":[171],"organ":[172],"local":[174],"morphology":[175],"can":[176,395],"influence":[177],"at":[180],"distant":[181],"regions.":[182],"Through":[183],"our":[184,256],"methods":[185,218,258,390],"it":[186],"possible":[188],"perform":[190],"cross":[192,205],"correlation":[193,206,233],"between":[195,271,290],"incorporating":[197],"all":[198],"voxels.":[200],"By":[201],"reducing":[202],"large":[204],"matrix":[207],"useful":[209],"statistics":[210],"new":[211,251],"aspects":[212],"revealed.":[216],"introduced":[219,391],"simple,":[221],"easy":[222],"implement":[224],"efficient.":[226],"another":[228],"effort":[229],"modify":[231],"canonical":[232],"(CCA)":[235],"fuse":[237],"two":[238],"sets":[239],"locate":[244],"regions":[246,295,351],"significant":[248],"correlations.":[249,360],"differential":[252],"features":[253],"identified":[254],"through":[255],"used":[260],"classify":[262],"subjects.":[263],"sMRI\u2013fMRI":[265],"indicates":[267,349],"linkage":[270],"gray":[272],"matter":[273],"probed":[277],"by":[278],"sensorimotor":[280],"task":[281],"weaker":[283],"SZ":[285,321],"than":[286,328],"HC.":[288,330],"Linkages":[289],"cerebellum":[298],"prefrontal":[301],"cortex":[302],"found":[304],"be":[306,396],"aberrant":[307],"SZ.":[309],"pair":[311],"wise":[312],"four":[315],"tasks":[318,325],"shows":[319],"activate":[322],"uniquely":[327],"do":[329],"above":[332],"results":[333,374],"support":[334],"\u2018disconnection":[336],"hypothesis\u2019":[337],"\u2018theory":[342],"cognitive":[344],"dysmetria\u2019.":[345],"DTI\u2013symptom":[346,359],"score":[347],"superior":[354],"longitudinal":[355],"fasciculus":[356],"high":[358,366],"Our":[361],"preliminary":[362],"classification":[363],"efforts":[364],"show":[365],"success":[367],"rates":[368],"leave\u2013one\u2013out":[371],"scheme.":[372],"presented":[375],"several":[380],"novel":[381],"interesting":[383],"findings":[384],"better":[386],"understand":[387],"general,":[393],"easily":[397],"applied":[398],"pathological":[403],"explore":[407],"behavior.":[409]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}