{"id":"https://openalex.org/W92280384","doi":null,"title":"Nocturnal elevation of intraocular pressure in young adults.","display_name":"Nocturnal elevation of intraocular pressure in young adults.","publication_year":1998,"publication_date":"1998-12-01","ids":{"openalex":"https://openalex.org/W92280384","mag":"92280384","pmid":"https://pubmed.ncbi.nlm.nih.gov/9856781"},"language":"en","primary_location":{"id":"pmid:9856781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9856781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055338307","display_name":"J H Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J H Liu","raw_affiliation_strings":["Department of Ophthalmology, University of California San Diego, La Jolla 92093-0946, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, University of California San Diego, La Jolla 92093-0946, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058840955","display_name":"D F Kripke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D F Kripke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026639773","display_name":"R E Hoffman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R E Hoffman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009749990","display_name":"Michael D. Twa","orcid":"https://orcid.org/0000-0003-4544-5153","observed_orcids":["https://orcid.org/0000-0003-4544-5153"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M D Twa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037247779","display_name":"Richard T. Loving","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R T Loving","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012879749","display_name":"Katharine M. Rex","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K M Rex","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056569020","display_name":"Neeru Gupta","orcid":"https://orcid.org/0000-0001-8141-7710","observed_orcids":["https://orcid.org/0000-0001-8141-7710"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Gupta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5043994887","display_name":"Robert Neal Weinreb","orcid":"https://orcid.org/0000-0001-9553-3202","observed_orcids":["https://orcid.org/0000-0001-9553-3202","https://orcid.org/0000-0003-4217-4853"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R N Weinreb","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6133,"has_fulltext":false,"cited_by_count":278,"citation_normalized_percentile":{"value":0.92470965,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"39","issue":"13","first_page":"2707","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11291","display_name":"Intraocular Surgery and Lenses","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraocular-pressure","display_name":"intraocular pressure","score":0.9919999837875366},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.9160000085830688},{"id":"https://openalex.org/keywords/posture-effects","display_name":"posture effects","score":0.6880000233650208},{"id":"https://openalex.org/keywords/supine-position","display_name":"supine position","score":0.6729999780654907},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.6100000143051147},{"id":"https://openalex.org/keywords/light-exposure","display_name":"light exposure","score":0.6439999938011169},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.42100000381469727}],"concepts":[{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.8698699474334717},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.8163899779319763},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.676461935043335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6170032024383545},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5511358976364136},{"id":"https://openalex.org/C2776370487","wikidata":"https://www.wikidata.org/wiki/Q1144593","display_name":"Sitting","level":2,"score":0.5240205526351929},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3040318191051483},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1318020224571228},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011187","descriptor_name":"Posture","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014065","descriptor_name":"Tonometry, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9856781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9856781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Journal Article"},{"id":"mag:92280384","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9856781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5234734580","display_name":"REGULATION OF INTRAOCULAR PRESSURE AND OCULAR BLOOD FLOW","funder_award_id":"R01EY007544","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W26461920","https://openalex.org/W44266720","https://openalex.org/W85435396","https://openalex.org/W87869944","https://openalex.org/W93259927","https://openalex.org/W112803784","https://openalex.org/W132383818","https://openalex.org/W194425808","https://openalex.org/W625501356","https://openalex.org/W1509486800","https://openalex.org/W1554147929","https://openalex.org/W1579688353","https://openalex.org/W1830741797","https://openalex.org/W1963733459","https://openalex.org/W1983103567","https://openalex.org/W1987984585","https://openalex.org/W1999696341","https://openalex.org/W1999771550","https://openalex.org/W2008008690","https://openalex.org/W2008396068","https://openalex.org/W2009875540","https://openalex.org/W2019027680","https://openalex.org/W2019701761","https://openalex.org/W2023358537","https://openalex.org/W2028583482","https://openalex.org/W2047097816","https://openalex.org/W2054348675","https://openalex.org/W2074871385","https://openalex.org/W2079194549","https://openalex.org/W2089398241","https://openalex.org/W2092846223","https://openalex.org/W2102876001","https://openalex.org/W2190492937","https://openalex.org/W2560497666"],"related_works":["https://openalex.org/W2034107636","https://openalex.org/W53927340","https://openalex.org/W123095488","https://openalex.org/W2089398241","https://openalex.org/W2023358537","https://openalex.org/W37008971","https://openalex.org/W2105105898","https://openalex.org/W1974939259","https://openalex.org/W2003780479","https://openalex.org/W2313690851"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"distinguish":[2],"24-hour":[3,200],"(circadian)":[4],"and":[5,34,96,145,180],"postural":[6],"effects":[7],"on":[8],"intraocular":[9],"pressure":[10,46,172,195],"(IOP)":[11],"in":[12,21,41,49,66,88,124,129,133,140,150,158,167,208,215,233,240],"healthy":[13],"young":[14,234],"adults.":[15],"METHODS:":[16],"Thirty-three":[17],"volunteers":[18],"were":[19,84,112,231],"housed":[20],"a":[22,29,56],"sleep":[23],"laboratory":[24],"for":[25],"1":[26],"day":[27],"under":[28],"strictly":[30],"controlled":[31],"16-hour":[32],"light":[33,72,179],"8-hour":[35],"dark":[36,43,100,126,153,243],"environment.":[37],"Sleep":[38],"was":[39,47,74,121,160,190,219],"encouraged":[40],"the":[42,67,70,77,89,93,99,103,115,125,130,141,146,151,168,176,183,186,199,205,209,212,216,223,237,241,267],"period.":[44,101,201,225,244],"Intraocular":[45,171,194],"measured":[48],"each":[50],"eye":[51],"every":[52],"2":[53],"hours":[54],"using":[55],"pneumatonometer.":[57],"Researchers":[58],"used":[59],"night-vision":[60],"goggles":[61],"to":[62,262,266],"perform":[63],"IOP":[64,110,120,138,148,159,188,207,214,230,247,270],"measurements":[65,83,111],"dark,":[68],"while":[69],"subject's":[71],"exposure":[73],"minimized.":[75],"In":[76,102,182,202],"first":[78,169,210],"group":[79,105,218],"of":[80,106,229,252,258],"12":[81],"subjects,":[82,108],"taken":[85,113],"with":[86,114,204,236],"subjects":[87,116],"sitting":[90,206],"position":[91,254],"during":[92,98,222],"light-wake":[94,131,143,224],"period":[95,127,132],"supine":[97,213],"second":[104,184,217],"21":[107],"all":[109],"supine.":[117],"RESULTS:":[118],"Average":[119],"significantly":[122,220],"higher":[123,221],"than":[128],"both":[134],"groups.":[135],"The":[136,155],"lowest":[137],"occurred":[139,149],"last":[142,152],"measurement,":[144],"peak":[147],"measurement.":[154],"trough-peak":[156,187],"difference":[157,189],"8.2+/-1.4":[161],"mm":[162,192],"Hg":[163],"(mean":[164],"+/-":[165],"SEM)":[166],"group.":[170],"changed":[173,196],"sharply":[174],"at":[175],"transitions":[177],"between":[178],"dark.":[181],"group,":[185,211],"3.8+/-0.9":[191],"Hg.":[193],"gradually":[197],"throughout":[198],"comparison":[203],"CONCLUSIONS:":[226],"Circadian":[227],"rhythms":[228],"shown":[232],"adults,":[235],"peaks":[238],"occurring":[239],"late":[242],"A":[245],"nocturnal":[246,269],"elevation":[248],"can":[249],"appear":[250],"independent":[251],"body":[253],"change,":[255],"but":[256],"change":[257],"posture":[259],"from":[260],"upright":[261],"recumbent":[263],"may":[264],"contribute":[265],"relative":[268],"elevation.":[271]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":21},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}