{"id":"https://openalex.org/W92122859","doi":null,"title":"Examination of nervous system effects and other health effects in tunnel workers exposed to acrylamide and N-methylolacrylamide in Romeriksporten, Norway","display_name":"Examination of nervous system effects and other health effects in tunnel workers exposed to acrylamide and N-methylolacrylamide in Romeriksporten, Norway","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W92122859","mag":"92122859"},"language":"en","primary_location":{"id":"pmh:oai:stami.brage.unit.no:11250/288415","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/288415","pdf_url":"http://hdl.handle.net/11250/288415","source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/report"},"volume":null,"type":"report","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11250/288415","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073353861","display_name":"Helge Kjuus","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Helge Kjuus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031155719","display_name":"Lars Ole Goffeng","orcid":"https://orcid.org/0000-0002-5227-9344","observed_orcids":["https://orcid.org/0000-0002-5227-9344"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lars Ole Goffeng","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5227-9344","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104364466","display_name":"Mona Skard Heier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mona Skard Heier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031035593","display_name":"Steinar \u00d8vreb\u00f8","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steinar \u00d8vreb\u00f8","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029703491","display_name":"Vidar Skaug","orcid":"https://orcid.org/0000-0002-5226-2681","observed_orcids":["https://orcid.org/0000-0002-5226-2681"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vidar Skaug","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5226-2681","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002342254","display_name":"David Ryberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Ryberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051470351","display_name":"Hans Sj\u00f6holm","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hans Sj\u00f6holm","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111456061","display_name":"Inger\u2010Lise Hansteen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Inger\u2010Lise Hansteen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022617563","display_name":"Margretha T\u00f6rnqvist","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margretha T\u00f6rnqvist","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048491299","display_name":"Birgit Paulsson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Birgit Paulsson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076994772","display_name":"Bj\u00f8rn T. Langeland","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bj\u00f8rn T. Langeland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049242464","display_name":"Stein Brudal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stein Brudal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066592720","display_name":"\u00d8rn Terje Foss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d8rn Terje Foss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11745","display_name":"Potato Plant Research","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11745","display_name":"Potato Plant Research","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13315","display_name":"Occupational Health and Safety in Workplaces","score":0.04989999905228615,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acrylamide","display_name":"acrylamide","score":0.9800000190734863},{"id":"https://openalex.org/keywords/n-hydroxymethyl-acrylamide","display_name":"N-methylolacrylamide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tunnel-workers","display_name":"tunnel workers","score":0.968999981880188},{"id":"https://openalex.org/keywords/occupational-exposure","display_name":"occupational exposure","score":0.6589999794960022},{"id":"https://openalex.org/keywords/nerve-conduction-velocity","display_name":"nerve conduction velocity","score":0.6890000104904175},{"id":"https://openalex.org/keywords/sensory-nerve-conduction","display_name":"sensory nerve conduction","score":0.7689999938011169},{"id":"https://openalex.org/keywords/ulnar-nerve","display_name":"ulnar nerve","score":0.656000018119812},{"id":"https://openalex.org/keywords/median-nerve","display_name":"median nerve","score":0.9430000185966492},{"id":"https://openalex.org/keywords/sensory-nerve-action-potential","display_name":"sensory nerve action potential","score":0.5070000290870667},{"id":"https://openalex.org/keywords/visual-evoked-potentials","display_name":"visual evoked potentials","score":0.7080000042915344},{"id":"https://openalex.org/keywords/electroretinography","display_name":"electroretinogram","score":0.9679999947547913},{"id":"https://openalex.org/keywords/hemoglobin-adducts","display_name":"hemoglobin adducts","score":0.8489999771118164},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.9750000238418579},{"id":"https://openalex.org/keywords/chromatid-gaps","display_name":"chromatid gaps","score":0.902999997138977},{"id":"https://openalex.org/keywords/grouting","display_name":"grouting","score":0.48899999260902405},{"id":"https://openalex.org/keywords/post-exposure-recovery","display_name":"recovery after exposure","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C2779402116","wikidata":"https://www.wikidata.org/wiki/Q342939","display_name":"Acrylamide","level":4,"score":0.6777409315109253},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6565732955932617},{"id":"https://openalex.org/C2779746960","wikidata":"https://www.wikidata.org/wiki/Q332293","display_name":"Carpal tunnel syndrome","level":2,"score":0.6438151597976685},{"id":"https://openalex.org/C179253579","wikidata":"https://www.wikidata.org/wiki/Q6276958","display_name":"Nerve conduction velocity","level":2,"score":0.6099786758422852},{"id":"https://openalex.org/C2776458010","wikidata":"https://www.wikidata.org/wiki/Q23786","display_name":"Eye color","level":3,"score":0.5569444298744202},{"id":"https://openalex.org/C2778931672","wikidata":"https://www.wikidata.org/wiki/Q254580","display_name":"Ulnar nerve","level":3,"score":0.5333345532417297},{"id":"https://openalex.org/C2775907655","wikidata":"https://www.wikidata.org/wiki/Q2635510","display_name":"Sensory nerve","level":3,"score":0.497847318649292},{"id":"https://openalex.org/C2779110535","wikidata":"https://www.wikidata.org/wiki/Q1364876","display_name":"Median nerve","level":2,"score":0.4301723837852478},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.4238091707229614},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.4180905222892761},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35267430543899536},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.333839476108551},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28478866815567017},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.13011053204536438},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.10937541723251343},{"id":"https://openalex.org/C2781184374","wikidata":"https://www.wikidata.org/wiki/Q42586","display_name":"Elbow","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:stami.brage.unit.no:11250/288415","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/288415","pdf_url":"http://hdl.handle.net/11250/288415","source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/report"},{"id":"pmh:oai:openarchive.usn.no:11250/2439278","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/2439278","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/report"},{"id":"mag:92122859","doi":null,"is_oa":false,"landing_page_url":"https://brage.bibsys.no/xmlui/handle/11250/2439278","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:stami.brage.unit.no:11250/288415","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/288415","pdf_url":"http://hdl.handle.net/11250/288415","source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/report"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W92122859.pdf","grobid_xml":"https://content.openalex.org/works/W92122859.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W41308541","https://openalex.org/W46370401","https://openalex.org/W189590033","https://openalex.org/W1042522063","https://openalex.org/W1489071388","https://openalex.org/W1831259184","https://openalex.org/W1883482843","https://openalex.org/W1961969173","https://openalex.org/W1963634283","https://openalex.org/W1968637118","https://openalex.org/W1973075579","https://openalex.org/W1973564273","https://openalex.org/W1974895891","https://openalex.org/W1975973052","https://openalex.org/W1984526404","https://openalex.org/W1992683123","https://openalex.org/W2002976054","https://openalex.org/W2005373772","https://openalex.org/W2005405521","https://openalex.org/W2005901865","https://openalex.org/W2007263773","https://openalex.org/W2007418168","https://openalex.org/W2007531409","https://openalex.org/W2010128992","https://openalex.org/W2021450808","https://openalex.org/W2023335568","https://openalex.org/W2023474291","https://openalex.org/W2024805816","https://openalex.org/W2033298355","https://openalex.org/W2043161194","https://openalex.org/W2057215289","https://openalex.org/W2057474661","https://openalex.org/W2057583631","https://openalex.org/W2068287372","https://openalex.org/W2081742199","https://openalex.org/W2097765108","https://openalex.org/W2126036294","https://openalex.org/W2126141337","https://openalex.org/W2147080306","https://openalex.org/W2150005688","https://openalex.org/W2170963316","https://openalex.org/W2321923744","https://openalex.org/W2327026770","https://openalex.org/W2418839968","https://openalex.org/W2469855636"],"related_works":["https://openalex.org/W7065774022","https://openalex.org/W2315468778","https://openalex.org/W2027296849","https://openalex.org/W2320140084","https://openalex.org/W1992410627","https://openalex.org/W2164378985","https://openalex.org/W2505888914","https://openalex.org/W2762849064","https://openalex.org/W2057474661","https://openalex.org/W2023474291"],"abstract_inverted_index":{"OBJECTIVES:":[0],"This":[1],"study":[2],"examined":[3,99],"nervous":[4,370],"system":[5,371],"effects":[6,10,366,401,423],"and":[7,17,24,37,43,55,70,85,95,105,111,167,218,221,223,295,308,320,380],"other":[8],"health":[9],"in":[11,30,100,139,146,213,234,239,249,261,272,285,326,331,372,396,418,427],"tunnel":[12,20,32,78,373],"workers":[13,33,79,118,374],"exposed":[14,34,103,117,274,306,333],"to":[15,35,108,129,158,205,277,291,355,376,378,404],"acrylamide":[16,36,67,381],"N-methylolacrylamide":[18,38,379],"during":[19,39,125,382],"work.":[21],"METHODS:":[22],"Symptoms":[23],"nerve":[25,142,149,216,226,242,252],"conduction":[26,143],"properties":[27],"were":[28,58,68,74,97,106,180,210,253,269,281],"recorded":[29],"25":[31,102,109,305,309],"grouting":[40,126,383],"operations,":[41],"four":[42,204],"16":[44,60,133,206,257,410],"months":[45,61,153,207,411],"after":[46,132,256],"the":[47,86,101,130,147,159,193,198,214,224,235,240,250,262,273,278,286,304,311,332,358,368,397,400,419,428,432,437],"cessation":[48],"of":[49,66,88,123,197,310,350,431,436],"exposure.":[50,63,413],"Visual":[51],"evoked":[52],"response":[53],"(VEP)":[54],"electroretinography":[56,263],"(ERG)":[57],"performed":[59],"post":[62,154,208,412],"Hemoglobin":[64],"adducts":[65],"measured":[69,184],"qualitative":[71,194],"exposure":[72,155,195,209,377],"indices":[73,196],"developed.":[75],"Fifty":[76],"unexposed":[77],"served":[80],"as":[81],"referents.":[82,114,279],"Chromosome":[83,297],"aberrations":[84],"distribution":[87],"Glutathion":[89],"S":[90],"transferase":[91],"(GST)":[92],"genotypes":[93,293],"(M":[94],"T)":[96],"also":[98,244],"workers,":[104,200],"compared":[107,128,157,276,354],"age":[110],"smoking":[112],"matched":[113],"RESULTS:":[115],"The":[116,259,362,434],"reported":[119],"an":[120],"increased":[121],"prevalence":[122],"symptoms":[124],"work":[127],"examination":[131],"months.":[134,258],"A":[135,230,323,414],"statistically":[136],"significant":[137,231,301,324],"reduction":[138,233],"mean":[140,168,236],"sensory":[141,219,237,247,394],"velocity":[144],"(NCV)":[145],"ulnar":[148,169,225],"was":[150,172,243,329],"observed":[151,211,330],"4":[152],"when":[156,183],"reference":[160],"group":[161],"(52.3":[162],"vs.":[163],"58.9":[164],"m/s,":[165],"p=0.001),":[166],"distal":[170],"delay":[171],"prolonged":[173],"(3.1":[174],"vs":[175],"2.5ms,":[176],"p=0.001).":[177],"Both":[178],"measures":[179],"significantly":[181,254,270],"improved":[182],"one":[185],"year":[186],"later.":[187],"By":[188],"correlating":[189],"outcome":[190,288],"measurements":[191],"with":[192,343,357,408],"individual":[199],"exposure-related":[201],"improvements":[202],"from":[203,386],"both":[212],"median":[215,241],"(motor":[217],"NCV":[220],"F-response)":[222],"(sensory":[227],"NCV,":[228],"F-response).":[229],"reversible":[232],"amplitude":[238],"observed,":[245],"while":[246],"amplitudes":[248,260],"sural":[251,398],"reduced":[255],"on":[264,367,393,424],"photoptic":[265],"(30":[266],"Hz)":[267],"stimulation":[268],"lower":[271],"subjects":[275,307],"There":[280],"no":[282,300,336],"clear":[283],"differences":[284,302],"neurophysiological":[287],"parameters":[289,353],"related":[290,375],"GST":[292],"M":[294],"T.":[296],"examinations":[298],"showed":[299],"between":[303],"referents":[312,356],"for":[313],"chromosome":[314,318,321,438],"aberrations,":[315],"chromatid":[316,327],"breaks,":[317],"breaks":[319],"gaps.":[322],"increase":[325],"gaps":[328],"subjects,":[334],"but":[335],"exposureresponse":[337],"relationship":[338],"could":[339],"be":[340],"found.":[341],"Subjects":[342],"GSTM1-/GSTT1":[344],"genotype":[345],"had":[346],"slightly":[347],"higher":[348],"frequencies":[349],"all":[351],"effect":[352,392],"same":[359],"genotype.":[360],"CONCLUSION:":[361],"results":[363,439],"indicate":[364,441],"slight":[365,416,444],"peripheral":[369],"operations.":[384],"Apart":[385],"a":[387,442],"3":[388],"possible":[389,415,443],"delayed":[390],"axonal":[391],"fibres":[395],"nerve,":[399],"seemed":[402],"largely":[403],"have":[405],"been":[406],"reversible,":[407],"normalisation":[409],"change":[417],"ERG":[420],"suggests":[421],"subclinical":[422],"photoreceptors":[425],"(cones)":[426],"central":[429],"part":[430],"retina.":[433],"pattern":[435],"may":[440],"genotoxic":[445],"effect.":[446]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
