{"id":"https://openalex.org/W915567808","doi":null,"title":"The gastrointestinal tract: safety pharmacology aspects relating to ageing, diet and natural/herbal remedies","display_name":"The gastrointestinal tract: safety pharmacology aspects relating to ageing, diet and natural/herbal remedies","publication_year":2009,"publication_date":"2009-12-31","ids":{"openalex":"https://openalex.org/W915567808","mag":"915567808"},"language":"en","primary_location":{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/fd0aa830-67e5-11df-928f-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/fd0aa830-67e5-11df-928f-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bartels , E M & Harrison , A P 2009 , ' The gastrointestinal tract : safety pharmacology aspects relating to ageing, diet and natural/herbal remedies ' , The Journal of Pre-Clinical and Clinical Research , vol. 3 , no. 2 , pp. 76-83 . < http://www.jpccr.eu/archive_pdf/2009_vol_3_nr_2/76_jpccr.pdf >","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.jpccr.eu/pdf-71306-8538?filename=The gastrointestinal.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005994510","display_name":"Else Marie Bartels","orcid":"https://orcid.org/0000-0001-9302-9678","observed_orcids":["https://orcid.org/0000-0001-9302-9678"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801150652","display_name":"Frederiksberg Hospital","ror":"https://ror.org/00d264c35","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801150652","https://openalex.org/I2802567020"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Else Marie Bartels","raw_affiliation_strings":["Copenhagen University Library, and The Parker Institute, Frederiksberg Hospital, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-9302-9678","affiliations":[{"raw_affiliation_string":"Copenhagen University Library, and The Parker Institute, Frederiksberg Hospital, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801150652"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079866195","display_name":"Adrian Paul Harrison","orcid":"https://orcid.org/0000-0002-6495-5629","observed_orcids":["https://orcid.org/0000-0002-6495-5629"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Adrian P. Harrison","raw_affiliation_strings":["Department of Animal and Veterinary Basic Sciences, Faculty of Life Science, Copenhagen University, Gronnegaardsvej 7, 1870 Frederiksberg C, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-6495-5629","affiliations":[{"raw_affiliation_string":"Department of Animal and Veterinary Basic Sciences, Faculty of Life Science, Copenhagen University, Gronnegaardsvej 7, 1870 Frederiksberg C, Denmark","institution_ids":["https://openalex.org/I124055696"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3216,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.66619357,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"3","issue":"2","first_page":"76","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.5067999958992004,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.5067999958992004,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.05820000171661377,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.05779999867081642,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastrointestinal-tract","display_name":"gastrointestinal tract","score":0.9729999899864197},{"id":"https://openalex.org/keywords/safety-pharmacology","display_name":"safety pharmacology","score":0.9539999961853027},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9620000123977661},{"id":"https://openalex.org/keywords/food-drug-interactions","display_name":"food-drug interactions","score":0.7049999833106995},{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.7260000109672546},{"id":"https://openalex.org/keywords/dietary-supplements","display_name":"dietary supplements","score":0.7699999809265137},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.5440000295639038},{"id":"https://openalex.org/keywords/gastrointestinal-dysfunction","display_name":"gastrointestinal dysfunction","score":0.75},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6110572218894958},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5939124822616577},{"id":"https://openalex.org/C2993106767","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Alimentary tract","level":2,"score":0.4901812672615051},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.43821603059768677},{"id":"https://openalex.org/C2992581678","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Digestive tract","level":2,"score":0.4174356758594513},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11275818943977356}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/fd0aa830-67e5-11df-928f-000ea68e967b","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/fd0aa830-67e5-11df-928f-000ea68e967b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bartels , E M & Harrison , A P 2009 , ' The gastrointestinal tract : safety pharmacology aspects relating to ageing, diet and natural/herbal remedies ' , The Journal of Pre-Clinical and Clinical Research , vol. 3 , no. 2 , pp. 76-83 . < http://www.jpccr.eu/archive_pdf/2009_vol_3_nr_2/76_jpccr.pdf >","raw_type":"article"},{"id":"mag:915567808","doi":null,"is_oa":true,"landing_page_url":"http://www.jpccr.eu/pdf-71306-8538?filename=The gastrointestinal.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764897176","display_name":"Journal of Pre-Clinical and Clinical Research","issn_l":"1898-2395","issn":["1898-2395","1898-7516"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","poland-40"],"host_organization":"https://openalex.org/P4310317348","host_organization_name":"Institute of Rural Health","host_organization_lineage":["https://openalex.org/P4310317348"],"host_organization_lineage_names":["Institute of Rural Health"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pre-Clinical and Clinical Research","raw_type":null}],"best_oa_location":{"id":"mag:915567808","doi":null,"is_oa":true,"landing_page_url":"http://www.jpccr.eu/pdf-71306-8538?filename=The gastrointestinal.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764897176","display_name":"Journal of Pre-Clinical and Clinical Research","issn_l":"1898-2395","issn":["1898-2395","1898-7516"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","poland-40"],"host_organization":"https://openalex.org/P4310317348","host_organization_name":"Institute of Rural Health","host_organization_lineage":["https://openalex.org/P4310317348"],"host_organization_lineage_names":["Institute of Rural Health"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pre-Clinical and Clinical Research","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1535954586","https://openalex.org/W1830830895","https://openalex.org/W1965930828","https://openalex.org/W1967819133","https://openalex.org/W1976303750","https://openalex.org/W1981987556","https://openalex.org/W1984573859","https://openalex.org/W1984697848","https://openalex.org/W1996833759","https://openalex.org/W1999572328","https://openalex.org/W2011467210","https://openalex.org/W2012256652","https://openalex.org/W2016204588","https://openalex.org/W2024503799","https://openalex.org/W2025932485","https://openalex.org/W2026350350","https://openalex.org/W2027229185","https://openalex.org/W2036499052","https://openalex.org/W2037992963","https://openalex.org/W2044333108","https://openalex.org/W2055657831","https://openalex.org/W2060716969","https://openalex.org/W2061350896","https://openalex.org/W2062904391","https://openalex.org/W2076790286","https://openalex.org/W2083038818","https://openalex.org/W2092310487","https://openalex.org/W2100597228","https://openalex.org/W2117188242","https://openalex.org/W2123378758","https://openalex.org/W2127081952","https://openalex.org/W2132806259","https://openalex.org/W2153242842","https://openalex.org/W2159975314","https://openalex.org/W2170646111","https://openalex.org/W2257326324","https://openalex.org/W2260813979","https://openalex.org/W2405101239","https://openalex.org/W2993340959","https://openalex.org/W4407824355"],"related_works":["https://openalex.org/W2337916718","https://openalex.org/W2405735866","https://openalex.org/W7131790795","https://openalex.org/W1944173211","https://openalex.org/W2207991426","https://openalex.org/W2075885670","https://openalex.org/W2145094876","https://openalex.org/W2333789759","https://openalex.org/W2974193369","https://openalex.org/W4237097447"],"abstract_inverted_index":{"The":[0],"gastrointestinal":[1],"tract":[2],"(GIT)":[3],"has":[4],"always":[5],"been":[6],"and":[7,20,88,91,95,98,104,110],"remains":[8,38],"a":[9],"major":[10],"source":[11],"of":[12,16,26,47,51,62,72,78,85,101,114,118],"interest":[13],"in":[14,29,83,116],"terms":[15,84,117],"both":[17],"its":[18,21],"function,":[19],"malfunction.":[22],"Our":[23],"current":[24],"knowledge":[25],"age-related":[27],"changes":[28],"this":[30],"system,":[31],"as":[32,34,60],"well":[33],"drug-food":[35],"interactions,":[36],"however,":[37],"relatively":[39],"limited.":[40],"Paradoxically,":[41],"the":[42,48,70],"GIT":[43,73,93,120],"is":[44],"not":[45],"one":[46],"core":[49],"battery":[50],"tests":[52],"that":[53],"pharmaceutical":[54],"companies":[55],"are":[56,108,122],"obliged":[57],"to":[58,68],"investigate":[59],"part":[61],"drug":[63,90,102,119],"development.":[64],"This":[65],"review":[66],"aims":[67],"cover":[69],"basics":[71],"function":[74],"before":[75],"highlighting":[76],"aspects":[77,100],"relevance":[79],"for":[80],"safety":[81],"pharmacology":[82],"age,":[86],"cancerogenesis,":[87],"noth":[89],"diet-related":[92],"damage":[94],"dysfunction.":[96],"New":[97],"novel":[99],"delivery":[103],"drug-dietary":[105],"supplement":[106],"interactions":[107],"discusses":[109],"much":[111],"needed":[112],"areas":[113],"focus":[115],"testing":[121],"identified.":[123]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
