{"id":"https://openalex.org/W913558992","doi":"https://doi.org/10.3760/cma.j.issn.0412-4030.2009.06.001","title":"Drug susceptibility test for 16 Mycobacteria tuberculosis isolates from patients with cutaneous tuberculosis.","display_name":"Drug susceptibility test for 16 Mycobacteria tuberculosis isolates from patients with cutaneous tuberculosis.","publication_year":2009,"publication_date":"2009-06-15","ids":{"openalex":"https://openalex.org/W913558992","doi":"https://doi.org/10.3760/cma.j.issn.0412-4030.2009.06.001","mag":"913558992"},"language":"en","primary_location":{"id":"mag:913558992","doi":"https://doi.org/10.3760/cma.j.issn.0412-4030.2009.06.001","is_oa":false,"landing_page_url":"https://www.cabdirect.org/cabdirect/abstract/20093232577","pdf_url":null,"source":{"id":"https://openalex.org/S2764659248","display_name":"Chinese Journal of Dermatology","issn_l":"0412-4030","issn":["0412-4030"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4320800525","host_organization_name":"Chinese Medical Association","host_organization_lineage":["https://openalex.org/P4320800525"],"host_organization_lineage_names":["Chinese Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Dermatology","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068446181","display_name":"Caiping Zhang","orcid":"https://orcid.org/0000-0002-7395-2219","observed_orcids":["https://orcid.org/0000-0002-7395-2219"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Caiping Zhang","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":"https://orcid.org/0000-0002-7395-2219","affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076668920","display_name":"Ji Jiang","orcid":"https://orcid.org/0000-0001-9974-8171","observed_orcids":["https://orcid.org/0000-0001-9974-8171"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ji Jiang","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":"https://orcid.org/0000-0001-9974-8171","affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100342092","display_name":"Lin Lin","orcid":"https://orcid.org/0009-0008-8181-8758","observed_orcids":["https://orcid.org/0009-0008-8181-8758"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Lin","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":"https://orcid.org/0009-0008-8181-8758","affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101699895","display_name":"Yiqin Yang","orcid":"https://orcid.org/0000-0003-3479-5000","observed_orcids":["https://orcid.org/0000-0003-3479-5000"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiqin Yang","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":"https://orcid.org/0000-0003-3479-5000","affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103989060","display_name":"Pangen Cui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pangen Cui","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056860943","display_name":"Yumiao Feng","orcid":"https://orcid.org/0000-0001-5996-4654","observed_orcids":["https://orcid.org/0000-0001-5996-4654"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yumiao Feng","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":"https://orcid.org/0000-0001-5996-4654","affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048426938","display_name":"Xiaoyu Yue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyu Yue","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101929503","display_name":"Liang Zhao","orcid":"https://orcid.org/0000-0001-8841-351X","observed_orcids":["https://orcid.org/0000-0001-8841-351X"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Zhao","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113744007","display_name":"Xuesi Zeng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuesi Zeng","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110401156","display_name":"Qinxue Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinxue Wu","raw_affiliation_strings":["Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical college, Nanjing 210042, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100773094","display_name":"Hongsheng Wang","orcid":"https://orcid.org/0000-0001-5725-5053","observed_orcids":["https://orcid.org/0000-0001-5725-5053"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongsheng Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5725-5053","affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"6","first_page":"371","last_page":"373"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/cutaneous-tuberculosis","display_name":"cutaneous tuberculosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/drug-sensitivity","display_name":"drug sensitivity","score":0.6890000104904175},{"id":"https://openalex.org/keywords/streptomycin-resistance","display_name":"streptomycin resistance","score":0.9010000228881836},{"id":"https://openalex.org/keywords/isoniazid","display_name":"isoniazid","score":0.796999990940094},{"id":"https://openalex.org/keywords/rifampicin","display_name":"rifampicin","score":1.0},{"id":"https://openalex.org/keywords/ethambutol","display_name":"ethambutol","score":1.0},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C2776228421","wikidata":"https://www.wikidata.org/wiki/Q412318","display_name":"Ethambutol","level":4,"score":0.9705493450164795},{"id":"https://openalex.org/C2775843808","wikidata":"https://www.wikidata.org/wiki/Q192717","display_name":"Streptomycin","level":3,"score":0.9598178267478943},{"id":"https://openalex.org/C2776967927","wikidata":"https://www.wikidata.org/wiki/Q423169","display_name":"Isoniazid","level":3,"score":0.8750863075256348},{"id":"https://openalex.org/C2778607973","wikidata":"https://www.wikidata.org/wiki/Q422652","display_name":"Rifampicin","level":3,"score":0.8748316764831543},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.8370770215988159},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.8037118911743164},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6178689002990723},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.5716283321380615},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4521673619747162},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.4135287404060364},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40995627641677856},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3964240849018097},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0872596800327301}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:913558992","doi":"https://doi.org/10.3760/cma.j.issn.0412-4030.2009.06.001","is_oa":false,"landing_page_url":"https://www.cabdirect.org/cabdirect/abstract/20093232577","pdf_url":null,"source":{"id":"https://openalex.org/S2764659248","display_name":"Chinese Journal of Dermatology","issn_l":"0412-4030","issn":["0412-4030"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4320800525","host_organization_name":"Chinese Medical Association","host_organization_lineage":["https://openalex.org/P4320800525"],"host_organization_lineage_names":["Chinese Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Chinese Journal of Dermatology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2461421805","https://openalex.org/W2371600422","https://openalex.org/W2606351307","https://openalex.org/W2379743188","https://openalex.org/W2386802281","https://openalex.org/W2294026319","https://openalex.org/W2013395052","https://openalex.org/W2034648139","https://openalex.org/W2111280268","https://openalex.org/W2156027597"],"abstract_inverted_index":{"Objective":[0],"To":[1],"test":[2,53],"the":[3,21,54,74,104],"drug":[4],"susceptibility":[5,55],"of":[6,23,28,56,76,83,103,110,124,141],"16":[7,81],"Mycobactena":[8],"tuberculosis":[9,143],"isolates":[10,58],"from":[11,32],"patients":[12,33,147],"with":[13,34,148],"cutaneous":[14,35,149],"tuberculosis,and":[15,150],"to":[16,52,59,66,72,88,92,99,112],"provide":[17],"a":[18,108,122],"basis":[19],"for":[20],"treatment":[22],"this":[24],"entity.Methods":[25],"Sixteen":[26],"strains":[27,64,82],"mycobacterium":[29],"were":[30,38,70,86,97],"isolated":[31],"tuberculosis.and":[36],"they":[37],"consistently":[39],"identified":[40],"as":[41],"M.tuberculosis":[42],"by":[43],"biochemistry":[44],"and":[45,61,68,94,101,121],"molecular":[46],"biology.Absolute":[47],"concentration":[48],"method":[49],"was":[50,144],"used":[51],"these":[57,155],"isoniazid.streptomycin.rifampicin":[60],"ethambutol.For":[62],"two":[63],"resistant":[65,87,133],"streptomycin,PCR":[67],"sequencing":[69],"performed":[71],"analyse":[73],"mutation":[75,109],"rpsL":[77,105],"gene.Results":[78],"Out":[79],"ofthe":[80],"M":[84,142],"tuberculosis.2":[85],"streptomycin":[89,151],"but":[90],"sensitive":[91,98],"isoniazid,rifampicin":[93],"ethambutol,and":[95],"14":[96],"isoniazid,streptomycin,rifampicin":[100],"ethambutol.Sequencing":[102],"gene":[106],"revealed":[107],"AAG":[111],"AGG":[113],"at":[114,128],"codon":[115,129],"43":[116],"in":[117,131,146,154],"one":[118],"streptomycinresistant":[119],"strain":[120],"substitution":[123],"CGC":[125],"bv":[126],"CAC":[127],"54":[130],"another":[132],"strain.Conclusions":[134],"In":[135],"past":[136],"five":[137],"years,the":[138],"resistance":[139,152],"ratio":[140],"low":[145],"predominated":[153],"strains.\r\n\r\nKey":[156],"words:":[157],"\r\nMycobacterinm":[158],"tuberculosis;\u00a0Drug":[159],"resistance;\u00a0Streptomycin":[160],"resistance;\u00a0Genes,rpsL":[161]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}