{"id":"https://openalex.org/W91195684","doi":"https://doi.org/10.1023/a:1027367624250","title":"Effect of Guanine Nucleotides on [3H]Glutamate Binding and on Adenylate Cyclase Activity in Rat Brain Membranes","display_name":"Effect of Guanine Nucleotides on [3H]Glutamate Binding and on Adenylate Cyclase Activity in Rat Brain Membranes","publication_year":1997,"publication_date":"1997-02-01","ids":{"openalex":"https://openalex.org/W91195684","doi":"https://doi.org/10.1023/a:1027367624250","mag":"91195684","pmid":"https://pubmed.ncbi.nlm.nih.gov/9016844"},"language":"en","primary_location":{"id":"doi:10.1023/a:1027367624250","doi":"https://doi.org/10.1023/a:1027367624250","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1027367624250","pdf_url":null,"source":{"id":"https://openalex.org/S174790897","display_name":"Neurochemical Research","issn_l":"0364-3190","issn":["0364-3190","1573-6903"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurochemical Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083728010","display_name":"Maribel Antonello Rubin","orcid":"https://orcid.org/0000-0002-2763-9619","observed_orcids":["https://orcid.org/0000-0002-2763-9619"]},"institutions":[{"id":"https://openalex.org/I33501960","display_name":"Universidade Federal de Santa Maria","ror":"https://ror.org/01b78mz79","country_code":"BR","type":"education","lineage":["https://openalex.org/I33501960"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Maribel A. Rubin","raw_affiliation_strings":["Departamento de Quimica, Centro de Ci\u00eancias Naturais e Exatas, Universidade Federal de Santa Maria, RS, Brasil","Departamento de Qu\u00edmica, Centro de Ci\u00eancias Naturais e Exatas, Universidade Federal de Santa Maria, RS Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Quimica, Centro de Ci\u00eancias Naturais e Exatas, Universidade Federal de Santa Maria, RS, Brasil","institution_ids":["https://openalex.org/I33501960"]},{"raw_affiliation_string":"Departamento de Qu\u00edmica, Centro de Ci\u00eancias Naturais e Exatas, Universidade Federal de Santa Maria, RS Brasil","institution_ids":["https://openalex.org/I33501960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032762051","display_name":"Alan Castoldi Medeiros","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alan C. Medeiros","raw_affiliation_strings":["Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107468732","display_name":"Paula C. B. Rocha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Paula C. B. Rocha","raw_affiliation_strings":["Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043134992","display_name":"Carolina Becker Livi","orcid":"https://orcid.org/0000-0001-8389-2830","observed_orcids":["https://orcid.org/0000-0001-8389-2830","https://orcid.org/0000-0002-9878-9374"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carolina B. Livi","raw_affiliation_strings":["Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031357012","display_name":"Galo Ram\u0131\u0301rez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I63634437","display_name":"Universidad Aut\u00f3noma de Madrid","ror":"https://ror.org/01cby8j38","country_code":"ES","type":"education","lineage":["https://openalex.org/I63634437"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Galo Ramirez","raw_affiliation_strings":["Centro de Biologia Molecular (CSIC-UAM), Universidade Aut\u00f3noma, Canto Blanco, 28049, Madrid, Spain","Centro de Biologia Molecular (CSIC-UAM), Universidade Aut\u00f3noma, Canto Blanco, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Biologia Molecular (CSIC-UAM), Universidade Aut\u00f3noma, Canto Blanco, 28049, Madrid, Spain","institution_ids":["https://openalex.org/I63634437"]},{"raw_affiliation_string":"Centro de Biologia Molecular (CSIC-UAM), Universidade Aut\u00f3noma, Canto Blanco, Madrid, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I63634437"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088021168","display_name":"Diogo Onofre Souza","orcid":"https://orcid.org/0000-0002-4322-0404","observed_orcids":["https://orcid.org/0000-0002-4322-0404"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Diogo O. Souza","raw_affiliation_strings":["Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Bioci\u00eancias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Departamento de Bioquimica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5083728010"],"corresponding_institution_ids":["https://openalex.org/I33501960"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":0.5953,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.60480841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"22","issue":"2","first_page":"181","last_page":"187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.25119999051094055,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/guanine-nucleotides","display_name":"guanine nucleotides","score":0.9800000190734863},{"id":"https://openalex.org/keywords/guanosine-triphosphate","display_name":"GTP","score":0.4650000035762787},{"id":"https://openalex.org/keywords/gmppnp","display_name":"GMPPNP","score":0.9369999766349792},{"id":"https://openalex.org/keywords/adenylyl-cyclase-activation","display_name":"adenylate cyclase activation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/g-proteins","display_name":"G proteins","score":0.6899999976158142},{"id":"https://openalex.org/keywords/gtp-binding-site","display_name":"GTP binding site","score":0.7049999833106995},{"id":"https://openalex.org/keywords/brain-membranes","display_name":"brain membranes","score":0.6119999885559082},{"id":"https://openalex.org/keywords/magnesium-dependence","display_name":"magnesium dependence","score":0.5730000138282776},{"id":"https://openalex.org/keywords/glutamate-receptors","display_name":"glutamate receptors","score":0.40700000524520874}],"concepts":[{"id":"https://openalex.org/C118716","wikidata":"https://www.wikidata.org/wiki/Q5514725","display_name":"GTP'","level":3,"score":0.8834548592567444},{"id":"https://openalex.org/C180526460","wikidata":"https://www.wikidata.org/wiki/Q356240","display_name":"Adenylate kinase","level":3,"score":0.7236803770065308},{"id":"https://openalex.org/C2780069284","wikidata":"https://www.wikidata.org/wiki/Q5198121","display_name":"Cyclase","level":3,"score":0.6520886421203613},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5645946264266968},{"id":"https://openalex.org/C2778301229","wikidata":"https://www.wikidata.org/wiki/Q169313","display_name":"Guanine","level":4,"score":0.557338535785675},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.5420717597007751},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.5314335823059082},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5111861824989319},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.4870767891407013},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.4716980457305908},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4451969265937805},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3445429503917694},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.323827862739563},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.20027312636375427},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1689239740371704},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000262","descriptor_name":"Adenylyl Cyclases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006150","descriptor_name":"Guanine Nucleotides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006150","descriptor_name":"Guanine Nucleotides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006153","descriptor_name":"Guanosine Diphosphate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D006153","descriptor_name":"Guanosine Diphosphate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006157","descriptor_name":"Guanosine Monophosphate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006160","descriptor_name":"Guanosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006165","descriptor_name":"Guanylyl Imidodiphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013873","descriptor_name":"Thionucleotides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014316","descriptor_name":"Tritium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019204","descriptor_name":"GTP-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1027367624250","doi":"https://doi.org/10.1023/a:1027367624250","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1027367624250","pdf_url":null,"source":{"id":"https://openalex.org/S174790897","display_name":"Neurochemical Research","issn_l":"0364-3190","issn":["0364-3190","1573-6903"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurochemical Research","raw_type":"journal-article"},{"id":"pmid:9016844","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9016844","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurochemical research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W11163000","https://openalex.org/W52693212","https://openalex.org/W140981242","https://openalex.org/W419399639","https://openalex.org/W1480699529","https://openalex.org/W1517658624","https://openalex.org/W1553656232","https://openalex.org/W1775749144","https://openalex.org/W1964281319","https://openalex.org/W1970117738","https://openalex.org/W1973263618","https://openalex.org/W1980418226","https://openalex.org/W1987708264","https://openalex.org/W1991058897","https://openalex.org/W2002834813","https://openalex.org/W2011950546","https://openalex.org/W2020365380","https://openalex.org/W2020425432","https://openalex.org/W2020849439","https://openalex.org/W2027047679","https://openalex.org/W2029853453","https://openalex.org/W2031704980","https://openalex.org/W2035390423","https://openalex.org/W2036488150","https://openalex.org/W2039248264","https://openalex.org/W2040456704","https://openalex.org/W2043166209","https://openalex.org/W2046072956","https://openalex.org/W2065244342","https://openalex.org/W2066439059","https://openalex.org/W2072175811","https://openalex.org/W2075989245","https://openalex.org/W2084615461","https://openalex.org/W2100040827","https://openalex.org/W2105149671","https://openalex.org/W2128585269","https://openalex.org/W2163234545","https://openalex.org/W2282971899","https://openalex.org/W2409988114","https://openalex.org/W2415315172","https://openalex.org/W2443423449","https://openalex.org/W4248350370","https://openalex.org/W4406969475"],"related_works":["https://openalex.org/W1987708264","https://openalex.org/W1967443949","https://openalex.org/W2460443194","https://openalex.org/W2139571691","https://openalex.org/W2441616340","https://openalex.org/W2072175811","https://openalex.org/W2125752041","https://openalex.org/W2037749897","https://openalex.org/W2022627542","https://openalex.org/W2207066936"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}