{"id":"https://openalex.org/W90302954","doi":null,"title":"Identification of vulnerability among first-degree relatives of patients with schizophrenia.","display_name":"Identification of vulnerability among first-degree relatives of patients with schizophrenia.","publication_year":2012,"publication_date":"2012-09-01","ids":{"openalex":"https://openalex.org/W90302954","mag":"90302954","pmid":"https://pubmed.ncbi.nlm.nih.gov/23019286"},"language":"en","primary_location":{"id":"pmid:23019286","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23019286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075768380","display_name":"Solanki Rk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I164135366","display_name":"SMS Medical College","ror":"https://ror.org/02x3hmg72","country_code":"IN","type":"education","lineage":["https://openalex.org/I164135366"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R K Solanki","raw_affiliation_strings":["Department of Psychiatry, Sawai ManSingh Medical College, Jaipur, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Sawai ManSingh Medical College, Jaipur, India","institution_ids":["https://openalex.org/I164135366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067064965","display_name":"Mukesh Kumar Swami","orcid":"https://orcid.org/0000-0001-9870-8397","observed_orcids":["https://orcid.org/0000-0001-9870-8397"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M K Swami","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"P Singh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Singh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103249661","display_name":"Suresh Gupta","orcid":"https://orcid.org/0000-0002-5790-1366","observed_orcids":["https://orcid.org/0000-0002-5790-1366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Gupta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3991,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.62504725,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"22","issue":"3","first_page":"118","last_page":"25"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10565","display_name":"Psychopathy, Forensic Psychiatry, Sexual Offending","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9869999885559082},{"id":"https://openalex.org/keywords/first-degree-relatives","display_name":"first-degree relatives","score":0.9470000267028809},{"id":"https://openalex.org/keywords/familial-risk","display_name":"familial risk","score":0.6200000047683716},{"id":"https://openalex.org/keywords/schizotypy","display_name":"schizotypy","score":0.9200000166893005},{"id":"https://openalex.org/keywords/neurological-soft-signs","display_name":"neurological soft signs","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.8009999990463257},{"id":"https://openalex.org/keywords/vulnerability-indicators","display_name":"vulnerability indicators","score":0.7300000190734863},{"id":"https://openalex.org/keywords/early-detection","display_name":"early detection","score":0.746999979019165},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.5730000138282776},{"id":"https://openalex.org/keywords/discriminant-function-analysis","display_name":"discriminant function analysis","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6975813508033752},{"id":"https://openalex.org/C2777727901","wikidata":"https://www.wikidata.org/wiki/Q3099410","display_name":"Schizotypy","level":3,"score":0.6946424245834351},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5921320915222168},{"id":"https://openalex.org/C172467417","wikidata":"https://www.wikidata.org/wiki/Q1670397","display_name":"Neurocognitive","level":3,"score":0.5912243127822876},{"id":"https://openalex.org/C41771347","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Discriminant function analysis","level":2,"score":0.5779483318328857},{"id":"https://openalex.org/C2779862289","wikidata":"https://www.wikidata.org/wiki/Q25098571","display_name":"First-degree relatives","level":3,"score":0.5666497349739075},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5094624161720276},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.46300676465034485},{"id":"https://openalex.org/C187288502","wikidata":"https://www.wikidata.org/wiki/Q641118","display_name":"Personality","level":2,"score":0.4554940164089203},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.43568509817123413},{"id":"https://openalex.org/C2781350904","wikidata":"https://www.wikidata.org/wiki/Q861560","display_name":"Schizotypal personality disorder","level":3,"score":0.42657607793807983},{"id":"https://openalex.org/C2781204524","wikidata":"https://www.wikidata.org/wiki/Q2802443","display_name":"Diagnosis of schizophrenia","level":3,"score":0.42323383688926697},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25972771644592285},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.22018703818321228},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10754147171974182},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005190","descriptor_name":"Family","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009460","descriptor_name":"Neurologic Examination","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012565","descriptor_name":"Schizophrenic Psychology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012569","descriptor_name":"Schizotypal Personality Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012569","descriptor_name":"Schizotypal Personality Disorder","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012569","descriptor_name":"Schizotypal Personality Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:23019286","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23019286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan","raw_type":"Journal Article"},{"id":"mag:90302954","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23019286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W618310327","https://openalex.org/W1957898531","https://openalex.org/W1970366326","https://openalex.org/W1972556520","https://openalex.org/W1972797655","https://openalex.org/W1981116212","https://openalex.org/W1984156533","https://openalex.org/W1992844193","https://openalex.org/W1999521629","https://openalex.org/W2005970171","https://openalex.org/W2008515967","https://openalex.org/W2011567013","https://openalex.org/W2020362338","https://openalex.org/W2024113797","https://openalex.org/W2027569302","https://openalex.org/W2027732021","https://openalex.org/W2033262590","https://openalex.org/W2056715407","https://openalex.org/W2060099042","https://openalex.org/W2063603752","https://openalex.org/W2066674353","https://openalex.org/W2071903286","https://openalex.org/W2076548270","https://openalex.org/W2077558964","https://openalex.org/W2084597624","https://openalex.org/W2085364076","https://openalex.org/W2092130770","https://openalex.org/W2099828377","https://openalex.org/W2106013922","https://openalex.org/W2107642085","https://openalex.org/W2109699622","https://openalex.org/W2112489940","https://openalex.org/W2127834479","https://openalex.org/W2128845579","https://openalex.org/W2137214935","https://openalex.org/W2138021960","https://openalex.org/W2139095930","https://openalex.org/W2139557454","https://openalex.org/W2140824803","https://openalex.org/W2143814782","https://openalex.org/W2146738944","https://openalex.org/W2148772507","https://openalex.org/W2151295206","https://openalex.org/W2154004292","https://openalex.org/W2155515198","https://openalex.org/W2157744350","https://openalex.org/W2158350585","https://openalex.org/W2162540656","https://openalex.org/W2166025578","https://openalex.org/W2170391530","https://openalex.org/W2170972558","https://openalex.org/W2172067697","https://openalex.org/W2260653911"],"related_works":["https://openalex.org/W2076548270","https://openalex.org/W2019101642","https://openalex.org/W2077558964","https://openalex.org/W2063361963","https://openalex.org/W7216873827","https://openalex.org/W4239885448","https://openalex.org/W7097745296","https://openalex.org/W7100521156","https://openalex.org/W2408845334","https://openalex.org/W616255726"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"evaluate":[2],"the":[3,21,93,114,138,205,223],"status":[4],"of":[5,24,30,49,71,126,140,193,217,225],"schizotypy,":[6],"neurological":[7,156,184],"soft":[8,157,185],"signs,":[9,186],"and":[10,18,51,69,104,118,155,187,208],"cognitive":[11,189,198],"functions":[12],"as":[13,122,124],"vulnerability":[14,219],"markers":[15,220],"for":[16,27,35,86,231],"schizophrenia":[17,54],"to":[19,83,136,228],"investigate":[20],"potential":[22],"value":[23],"their":[25],"combination":[26,201],"early":[28],"identification":[29],"people":[31],"at":[32],"high":[33],"risk":[34,230],"schizophrenia.":[36,232],"METHODS:":[37],"A":[38],"cross-sectional":[39],"study":[40],"was":[41,111,134],"conducted.":[42],"Subjects":[43,74],"were":[44,62,81],"drawn":[45],"from":[46,66],"first-degree":[47,206],"relatives":[48,146],"inpatients":[50],"outpatients":[52],"with":[53],"(n":[55,59],"=":[56,60,153,161,173,213],"50).":[57],"Controls":[58],"30)":[61],"recruited":[63],"by":[64],"word-of-mouth":[65],"hospital":[67],"staff":[68],"attendants":[70],"hospitalised":[72],"patients.":[73],"who":[75],"met":[76],"inclusion":[77],"criteria":[78],"on":[79,167,196],"screening":[80],"subjected":[82],"selected":[84],"measures":[85,170,226],"assessment,":[87],"including":[88],"Schizotypal":[89,180],"Personality":[90,181],"Questionnaire-Brief":[91,182],"Version,":[92,183],"Cambridge":[94],"Neurological":[95],"Inventory,":[96],"digit":[97],"span":[98],"test,":[99,103],"paired":[100],"associate":[101],"learning":[102],"visuospatial":[105],"working":[106],"memory":[107],"matrix.":[108],"Statistical":[109],"analysis":[110,133,177],"completed":[112],"using":[113],"independent":[115],"t":[116],"test":[117],"significance":[119],"(p":[120],"value),":[121],"well":[123],"calculation":[125],"effect":[127,139],"size":[128],"(Cohen's":[129,151,159,171],"d).":[130],"Discriminant":[131,175],"function":[132,176],"used":[135,227],"determine":[137,229],"combining":[141],"assessment":[142],"measures.":[143],"RESULTS:":[144],"First-degree":[145],"showed":[147,178],"higher":[148],"schizotypy":[149],"scores":[150,195],"d":[152,160,172],"0.88)":[154],"signs":[158],"1.55).":[162],"They":[163],"scored":[164],"significantly":[165],"worse":[166],"all":[168],"neurocognitive":[169],"-1.27).":[174],"that":[179],"total":[188],"index":[190],"(the":[191],"sum":[192],"weighted":[194],"individual":[197],"scales)":[199],"in":[200],"better":[202],"discriminated":[203],"between":[204],"relative":[207],"control":[209],"groups":[210],"(Wilks'":[211],"\u03bb":[212],"0.54).":[214],"CONCLUSION:":[215],"Use":[216],"multiple":[218],"could":[221],"enhance":[222],"specificity":[224]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}