{"id":"https://openalex.org/W90138503","doi":null,"title":"Measurement of repair replication by equilibrium sedimentation","display_name":"Measurement of repair replication by equilibrium sedimentation","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W90138503","mag":"90138503"},"language":"en","primary_location":{"id":"mag:90138503","doi":null,"is_oa":false,"landing_page_url":"http://www.osti.gov/scitech/biblio/6057455-measurement-repair-replication-equilibrium-sedimentation","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111698949","display_name":"Charles Allen Smith","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles A. Smith","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068262437","display_name":"Priscilla K. Cooper","orcid":"https://orcid.org/0000-0002-3563-3647","observed_orcids":["https://orcid.org/0000-0002-3563-3647"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Priscilla K. Cooper","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3563-3647","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5003203263","display_name":"Philip C. Hanawalt","orcid":"https://orcid.org/0000-0003-2331-0768","observed_orcids":["https://orcid.org/0000-0003-2331-0768"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Philip C. Hanawalt","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2331-0768","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.3697,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.88558055,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"1","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/repair-replication","display_name":"repair replication","score":0.7870000004768372},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.8209999799728394},{"id":"https://openalex.org/keywords/sedimentation-equilibrium","display_name":"sedimentation equilibrium","score":0.7089999914169312},{"id":"https://openalex.org/keywords/cscl-density-gradient","display_name":"CsCl density gradient","score":0.8539999723434448},{"id":"https://openalex.org/keywords/bromodeoxyuridine","display_name":"bromodeoxyuridine","score":0.8059999942779541},{"id":"https://openalex.org/keywords/5-bromouracil","display_name":"5-bromouracil","score":0.9079999923706055},{"id":"https://openalex.org/keywords/dna-labeling","display_name":"DNA labeling","score":0.4009999930858612},{"id":"https://openalex.org/keywords/semiconservative-replication","display_name":"semiconservative replication","score":0.7039999961853027},{"id":"https://openalex.org/keywords/permeabilized-cells","display_name":"permeabilized cells","score":0.6639999747276306},{"id":"https://openalex.org/keywords/bacterial-dna-repair","display_name":"bacterial DNA repair","score":0.5139999985694885},{"id":"https://openalex.org/keywords/eukaryotic-dna-repair","display_name":"eukaryotic DNA repair","score":0.8339999914169312}],"concepts":[{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.7333016991615295},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.6280713081359863},{"id":"https://openalex.org/C2778892434","wikidata":"https://www.wikidata.org/wiki/Q1871401","display_name":"Density gradient","level":2,"score":0.5388637781143188},{"id":"https://openalex.org/C2778260397","wikidata":"https://www.wikidata.org/wiki/Q419861","display_name":"Bromodeoxyuridine","level":3,"score":0.5358167290687561},{"id":"https://openalex.org/C2777108182","wikidata":"https://www.wikidata.org/wiki/Q422464","display_name":"Thymidine","level":3,"score":0.5273338556289673},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.5175777673721313},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.4937675893306732},{"id":"https://openalex.org/C25642318","wikidata":"https://www.wikidata.org/wiki/Q1992532","display_name":"Incubation","level":2,"score":0.47176364064216614},{"id":"https://openalex.org/C64241487","wikidata":"https://www.wikidata.org/wiki/Q5205774","display_name":"DNA synthesis","level":3,"score":0.4547043442726135},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4263092279434204},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41072583198547363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39029109477996826},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3792497515678406},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34831494092941284},{"id":"https://openalex.org/C177322064","wikidata":"https://www.wikidata.org/wiki/Q750955","display_name":"Radiochemistry","level":1,"score":0.3470541834831238},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.15798106789588928},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10311004519462585},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:90138503","doi":null,"is_oa":false,"landing_page_url":"http://www.osti.gov/scitech/biblio/6057455-measurement-repair-replication-equilibrium-sedimentation","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1992548055","https://openalex.org/W2065100767","https://openalex.org/W2007335562","https://openalex.org/W1967125264","https://openalex.org/W2034494101","https://openalex.org/W2147226129","https://openalex.org/W2038384128","https://openalex.org/W2216564292","https://openalex.org/W2060683606","https://openalex.org/W2015947721"],"abstract_inverted_index":{"A":[0],"method":[1,29],"is":[2,53,89,113,128],"described":[3],"in":[4,14,38,57,78,149,176,182],"detail":[5],"for":[6,138],"measuring":[7],"repair":[8,36],"replication,":[9],"which":[10,42,88],"has":[11,30],"proven":[12],"useful":[13],"studies":[15],"with":[16,72,109,124],"bacteria,":[17],"as":[18,20],"well":[19],"many":[21],"eukaryotes,":[22],"including":[23],"protozoans":[24],"and":[25,46,76,107,132,136],"mammalian":[26],"cells.":[27],"The":[28,68,111,126,140,165],"also":[31],"been":[32],"utilized":[33],"to":[34,41,92,115,130,156,170],"study":[35],"replication":[37],"permeabilized":[39],"systems":[40],"the":[43,73,82,95,102,177,183],"nucleoside":[44],"triphosphates":[45],"macromolecules":[47],"may":[48],"be":[49],"added.":[50],"Cellular":[51],"DNA":[52,66,146,160,178],"prelabeled":[54],"by":[55],"growth":[56],"a":[58,79,116,150,187],"medium":[59,80],"containing":[60,81,142],"/sup":[61,64,90,122,168,171,174],"14/C-":[62],"or":[63,86],"32/P-labeled":[65],"precursors.":[67],"cells":[69,103],"are":[70,104,134,147],"treated":[71,108],"test":[74],"agent":[75],"incubated":[77],"density":[83,117,145,154,181],"label":[84,94],"5-bromouracil":[85],"5-bromodeoxyuridine,":[87],"3/H-labeled":[91],"radioactively":[93],"newly":[96],"synthesized":[97],"DNA.":[98,164],"After":[99],"further":[100,157],"incubation,":[101],"harvested,":[105],"lysed,":[106],"protease.":[110],"digest":[112],"made":[114],"of":[118,167,173,179,189],"1.72":[119],"g":[120],"ml":[121],"-1/":[123],"CsCl.":[125],"solution":[127],"centrifuged":[129],"equilibrium,":[131],"fractions":[133,141],"collected":[135],"assayed":[137],"radioactivity.":[139],"unreplicated":[143],"parental":[144,180],"rebanded":[148],"second":[151,184],"CsCl":[152],"equilibrium":[153],"gradient":[155,185],"resolve":[158],"repair-synthesized":[159],"from":[161],"semi-conservatively":[162],"replicated":[163],"ratio":[166],"3/H":[169],"32/P":[172],"14/C":[175],"provides":[186],"measure":[188],"repair.":[190]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}