{"id":"https://openalex.org/W901165204","doi":null,"title":"[Dissemination of the KPC carbapenemase producing Klebsiella pneumoniae in a hospital in Warsaw, Poland].","display_name":"[Dissemination of the KPC carbapenemase producing Klebsiella pneumoniae in a hospital in Warsaw, Poland].","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W901165204","mag":"901165204","pmid":"https://pubmed.ncbi.nlm.nih.gov/20564966"},"language":"pl","primary_location":{"id":"pmid:20564966","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20564966","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medycyna doswiadczalna i mikrobiologia","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023712149","display_name":"Katarzyna Piekarska","orcid":"https://orcid.org/0000-0002-1763-3475","observed_orcids":["https://orcid.org/0000-0002-1763-3475"]},"institutions":[{"id":"https://openalex.org/I4210101740","display_name":"Narodowy Instytut Zdrowia Publicznego PZH \u2013 Pa\u0144stwowy Instytut Badawczy","ror":"https://ror.org/015qjap30","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210101740"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Katarzyna Piekarska","raw_affiliation_strings":["Zak\u0142ad Bakteriologii, Narodowego Instytutu Zdrowia Publicznego-Pa\u0144stwowego Zak\u0142adu Higieny","Zaklad Bakteriologii, Narodowy Instytut Zdrowia Publicznego - Panstwowy Zaklad Higieny, ul.Chocimska 24, 00-791 Warszawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zak\u0142ad Bakteriologii, Narodowego Instytutu Zdrowia Publicznego-Pa\u0144stwowego Zak\u0142adu Higieny","institution_ids":["https://openalex.org/I4210101740"]},{"raw_affiliation_string":"Zaklad Bakteriologii, Narodowy Instytut Zdrowia Publicznego - Panstwowy Zaklad Higieny, ul.Chocimska 24, 00-791 Warszawa","institution_ids":["https://openalex.org/I4210101740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082836699","display_name":"Katarzyna Zacharczuk","orcid":"https://orcid.org/0000-0003-1476-2172","observed_orcids":["https://orcid.org/0000-0003-1476-2172"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katarzyna Zacharczuk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040861826","display_name":"Jolanta Szych","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jolanta Szych","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084749293","display_name":"Elwira Zawidzka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elwira Zawidzka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Elzbieta Wilk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elzbieta Wilk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113476595","display_name":"Sebastian Wardak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sebastian Wardak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109241512","display_name":"M Jagielski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marek Jagielski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5059276021","display_name":"Rafa\u0142 Gierczy\u0144ski","orcid":"https://orcid.org/0000-0002-2106-1203","observed_orcids":["https://orcid.org/0000-0002-2106-1203"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rafa\u0142 Gierczy\u0144ski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3607,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.62485018,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"62","issue":"1","first_page":"9","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13849","display_name":"Enterobacteriaceae and Cronobacter Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.968999981880188},{"id":"https://openalex.org/keywords/kpc-carbapenemase","display_name":"KPC carbapenemase","score":0.972000002861023},{"id":"https://openalex.org/keywords/kpc-2","display_name":"KPC-2","score":0.9520000219345093},{"id":"https://openalex.org/keywords/blakpc-gene","display_name":"blaKPC gene","score":0.796999990940094},{"id":"https://openalex.org/keywords/ertapenem-resistance","display_name":"ertapenem resistance","score":0.9490000009536743},{"id":"https://openalex.org/keywords/imipenem-resistance","display_name":"imipenem resistance","score":0.8240000009536743},{"id":"https://openalex.org/keywords/meropenem-resistance","display_name":"meropenem resistance","score":0.9860000014305115},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.5910000205039978},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.6809999942779541},{"id":"https://openalex.org/keywords/pulsed-field-gel-electrophoresis-genotyping","display_name":"pulsed-field gel electrophoresis genotyping","score":0.8510000109672546},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.7689999938011169},{"id":"https://openalex.org/keywords/warsaw","display_name":"Warsaw","score":0.4359999895095825}],"concepts":[{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.7391391396522522},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.4839058816432953},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.102304607629776},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09359407424926758},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001398","descriptor_name":"Aztreonam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002439","descriptor_name":"Cefotaxime","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002442","descriptor_name":"Ceftazidime","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002939","descriptor_name":"Ciprofloxacin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003091","descriptor_name":"Colistin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003428","descriptor_name":"Cross Infection","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007710","descriptor_name":"Klebsiella Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007710","descriptor_name":"Klebsiella Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D007710","descriptor_name":"Klebsiella Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011044","descriptor_name":"Poland","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024901","descriptor_name":"Drug Resistance, Multiple, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:20564966","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20564966","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medycyna doswiadczalna i mikrobiologia","raw_type":"Journal Article"},{"id":"mag:901165204","doi":null,"is_oa":false,"landing_page_url":"https://www.infona.pl/resource/bwmeta1.element.agro-article-0a60aeaa-0322-4f7d-9381-bd9c4afb7698","pdf_url":null,"source":{"id":"https://openalex.org/S2756427600","display_name":"Medycyna Do\u015bwiadczalna i Mikrobiologia","issn_l":"0025-8601","issn":["0025-8601","2545-2517"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4324001549","host_organization_name":"National Institute of Hygiene","host_organization_lineage":["https://openalex.org/P4324001549"],"host_organization_lineage_names":["National Institute of Hygiene"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Medycyna Do\u015bwiadczalna i Mikrobiologia","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1902535075","https://openalex.org/W1985044626","https://openalex.org/W2041550248","https://openalex.org/W2051762554","https://openalex.org/W2057857645","https://openalex.org/W2061729558","https://openalex.org/W2103732579","https://openalex.org/W2108124404","https://openalex.org/W2108129452","https://openalex.org/W2113758313","https://openalex.org/W2118217353","https://openalex.org/W2134438764","https://openalex.org/W2142047833","https://openalex.org/W2142513866","https://openalex.org/W2148493445","https://openalex.org/W2153834931","https://openalex.org/W2158541189","https://openalex.org/W2171929210"],"related_works":["https://openalex.org/W1763464308","https://openalex.org/W2525070605","https://openalex.org/W2601385681","https://openalex.org/W999692662","https://openalex.org/W1168657010","https://openalex.org/W6941164369","https://openalex.org/W2604260073","https://openalex.org/W2337705105","https://openalex.org/W7057440763","https://openalex.org/W2571129383"],"abstract_inverted_index":{"Within":[0],"the":[1,11,34,41,48,87,93,97,107,114,122,128,143,151,172,179,199,202,205,218,224,231,237,250,256,262,270,278,286,290,294,305],"last":[2],"decade,":[3],"human":[4],"infections":[5],"caused":[6],"by":[7,96,117,142,171,223],"enterobacteria":[8],"which":[9],"produce":[10],"Klebsiella":[12],"pneumoniae":[13,30,243,298],"carbapenemase":[14],"(KPC)":[15],"became":[16],"a":[17,68,77],"serious":[18],"therapeutic":[19],"and":[20,72,130,138,316],"epidemiological":[21],"problem":[22],"worldwide.":[23],"The":[24,60,146,226],"KPC":[25,88,163,295],"producing":[26,296],"strains":[27,307],"of":[28,57,67,76,86,100,127,150,162,184,190,217,230,240,293],"K.":[29,58,242,297],"broadly":[31],"disseminated":[32],"in":[33,45,82,91,212,299],"USA":[35],"then":[36],"spread":[37],"to":[38,112,136,169,255,267,269,311,320],"Europe.":[39],"Recently,":[40],"KPC-2":[42],"was":[43,89,182,252],"found":[44],"Poland.":[46,84,300],"In":[47,260],"presented":[49],"study":[50],"we":[51],"tested":[52,94,306],"11":[53],"ertapenem":[54],"resistant":[55,135,310],"isolates":[56,61,95,108,166,196,208,216,234,265],"pneumoniae.":[59],"were":[62,109,134,167,210,221,308],"obtained":[63],"from":[64,73,155,201],"10":[65],"patients":[66],"regular":[69],"hospital":[70,80],"(RH)":[71],"one":[74,200],"patient":[75],"palliative":[78,257],"care":[79,258],"(PH)":[81],"Warsaw,":[83],"Expression":[85],"confirmed":[90],"all":[92,131,304],"positive":[98],"result":[99],"phenotypic":[101],"test":[102],"with":[103,119,174,188],"boronic":[104],"acid.":[105],"All":[106],"also":[110,253,309],"shown":[111],"harbour":[113],"bla(KPC)":[115,153,279],"gene":[116,154,280],"PCR":[118],"primers":[120],"targeting":[121],"core":[123],"372":[124],"bp":[125],"fragment":[126],"gene,":[129],"but":[132,318],"two":[133,185,206],"imipenem":[137],"meropenem":[139],"as":[140],"determined":[141],"disc-diffusion":[144],"method.":[145],"DNA":[147],"sequence":[148],"analysis":[149],"complete":[152],"representative":[156],"isolate":[157],"DM0269":[158],"revealed":[159],"variant":[160],"2":[161],"(KPC-2).":[164],"Tested":[165],"subjected":[168],"genotyping":[170],"PFGE":[173,180],"XbaI.":[175],"Dendrogram":[176],"based":[177],"on":[178,289],"profiles":[181],"composed":[183],"main":[186],"branches":[187],"82,3%":[189],"similarity.":[191],"Branch":[192],"A":[193,220,233],"encompassed":[194],"9":[195],"(93,2%),":[197],"including":[198],"PH-patient,":[203],"while":[204],"remaining":[207],"(86,5%)":[209],"located":[211],"branch":[213,219,232,263],"B.":[214],"Five":[215],"indistinguishable":[222],"PFGE.":[225],"high":[227],"genetic":[228],"similarity":[229],"strongly":[235],"suggests":[236],"intra-hospital":[238,291],"dissemination":[239,292],"epidemic":[241],"KPC+":[244],"sensu":[245,272],"stricto":[246,273],"strain.":[247],"Most":[248],"probably,":[249],"strain":[251],"transferred":[254],"hospital.":[259],"contrast,":[261],"B":[264],"appear":[266],"belong":[268],"distinct":[271],"strain,":[274],"that":[275],"has":[276],"acquired":[277],"via":[281],"horizontal":[282],"transfer.":[283],"This":[284],"is":[285,302],"first":[287],"report":[288],"It":[301],"noteworthy,":[303],"cefotaxime,":[312],"ceftazidime,":[313],"aztreonam,":[314],"ciprofloxacin":[315],"sulphonamides,":[317],"sensitive":[319],"colistin.":[321]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}