{"id":"https://openalex.org/W90018186","doi":null,"title":"Tumors that acquire resistance to metronomic cyclophosphamide chemotherapy retain sensitivity to maximum tolerated dose cyclophosphoamide","display_name":"Tumors that acquire resistance to metronomic cyclophosphamide chemotherapy retain sensitivity to maximum tolerated dose cyclophosphoamide","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W90018186","mag":"90018186"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.utep.edu:bio_papers-1021","doi":null,"is_oa":false,"landing_page_url":"http://digitalcommons.utep.edu/bio_papers/22","pdf_url":null,"source":{"id":"https://openalex.org/S4306402377","display_name":"DigitalCommons@UTEP (The University of Texas at El Paso)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I164936912","host_organization_name":"The University of Texas at El Paso","host_organization_lineage":["https://openalex.org/I164936912"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Departmental Papers (Biology)","raw_type":"text"},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075999310","display_name":"Giulio Francia","orcid":"https://orcid.org/0000-0002-3752-3070","observed_orcids":["https://orcid.org/0000-0002-3752-3070"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Giulio Francia","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3752-3070","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5075999310"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00775759,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.1703999936580658,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.1703999936580658,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.11620000004768372,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.1046999990940094,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.9150000214576721},{"id":"https://openalex.org/keywords/metronomic-chemotherapy","display_name":"metronomic chemotherapy","score":0.9089999794960022},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.8399999737739563},{"id":"https://openalex.org/keywords/maximum-tolerated-dose","display_name":"maximum tolerated dose","score":0.6930000185966492},{"id":"https://openalex.org/keywords/tumor-sensitivity","display_name":"tumor sensitivity","score":0.5979999899864197},{"id":"https://openalex.org/keywords/chemotherapy-resistance-reversal","display_name":"chemotherapy resistance reversal","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.750068187713623},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6189252734184265},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.5637117624282837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5260450839996338},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3457608222961426},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34406304359436035},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06923893094062805},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digitalcommons.utep.edu:bio_papers-1021","doi":null,"is_oa":false,"landing_page_url":"http://digitalcommons.utep.edu/bio_papers/22","pdf_url":null,"source":{"id":"https://openalex.org/S4306402377","display_name":"DigitalCommons@UTEP (The University of Texas at El Paso)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I164936912","host_organization_name":"The University of Texas at El Paso","host_organization_lineage":["https://openalex.org/I164936912"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Departmental Papers (Biology)","raw_type":"text"},{"id":"mag:90018186","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.utep.edu/bio_papers/22/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1924587196","https://openalex.org/W2559999573","https://openalex.org/W2275293745","https://openalex.org/W2007480962","https://openalex.org/W2884117767","https://openalex.org/W3005165740","https://openalex.org/W2095581062","https://openalex.org/W4408742753","https://openalex.org/W7098627431","https://openalex.org/W7027023597"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2016-06-24T00:00:00"}