{"id":"https://openalex.org/W89580140","doi":null,"title":"Primary Sj\u00f6gren's syndrome: a subjective description of the disease.","display_name":"Primary Sj\u00f6gren's syndrome: a subjective description of the disease.","publication_year":1990,"publication_date":"1990-05-01","ids":{"openalex":"https://openalex.org/W89580140","mag":"89580140","pmid":"https://pubmed.ncbi.nlm.nih.gov/2379343"},"language":"en","primary_location":{"id":"pmid:2379343","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2379343","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental rheumatology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031237269","display_name":"Kirsten B. Bjerrum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"K Bjerrum","raw_affiliation_strings":["Eye Pathology Institute, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Pathology Institute, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109163111","display_name":"J. U. Prause","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J U Prause","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9901,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.77223899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"8","issue":"3","first_page":"283","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11282","display_name":"Fibromyalgia and Chronic Fatigue Syndrome Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-sjogren-syndrome","display_name":"primary Sj\u00f6gren's syndrome","score":1.0},{"id":"https://openalex.org/keywords/disease-onset","display_name":"disease onset","score":0.6650000214576721},{"id":"https://openalex.org/keywords/symptom-onset","display_name":"symptom onset","score":0.4300000071525574},{"id":"https://openalex.org/keywords/dry-eye-disease","display_name":"dry eye","score":0.9789999723434448},{"id":"https://openalex.org/keywords/xerostomia","display_name":"xerostomia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.8240000009536743},{"id":"https://openalex.org/keywords/muscle-and-joint-pain","display_name":"muscle and joint pain","score":0.8519999980926514},{"id":"https://openalex.org/keywords/age-of-onset","display_name":"age of onset","score":0.6480000019073486},{"id":"https://openalex.org/keywords/delayed-diagnosis","display_name":"delayed diagnosis","score":0.6439999938011169},{"id":"https://openalex.org/keywords/artificial-tears","display_name":"artificial tears","score":0.9760000109672546},{"id":"https://openalex.org/keywords/familial-predisposition","display_name":"familial predisposition","score":0.7590000033378601},{"id":"https://openalex.org/keywords/patient-experience","display_name":"patient experience","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9454623460769653},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6672937870025635},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5948588252067566},{"id":"https://openalex.org/C2909680690","wikidata":"https://www.wikidata.org/wiki/Q1162694","display_name":"KERATOCONJUNCTIVITIS SICCA","level":2,"score":0.5308809280395508},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.43426963686943054},{"id":"https://openalex.org/C38022665","wikidata":"https://www.wikidata.org/wiki/Q1149305","display_name":"Disposition","level":2,"score":0.41093704104423523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20464223623275757},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001964","descriptor_name":"Bromhexine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005221","descriptor_name":"Fatigue","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007638","descriptor_name":"Keratoconjunctivitis Sicca","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009059","descriptor_name":"Mouth Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010465","descriptor_name":"Perception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012859","descriptor_name":"Sjogren's Syndrome","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D012934","descriptor_name":"Social Isolation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014987","descriptor_name":"Xerostomia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2379343","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2379343","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental rheumatology","raw_type":"Journal Article"},{"id":"mag:89580140","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2379343","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4283709681","https://openalex.org/W2407035325","https://openalex.org/W4402919644","https://openalex.org/W2418353268","https://openalex.org/W2353385954","https://openalex.org/W4399484441","https://openalex.org/W4404959393","https://openalex.org/W2947407772","https://openalex.org/W2364185943","https://openalex.org/W1986336795"],"abstract_inverted_index":{"Forty":[0],"patients":[1,44,120,142,165,184],"with":[2],"primary":[3],"Sj\u00f6gren's":[4],"syndrome":[5],"were":[6,28],"interviewed":[7],"to":[8,33,96,108,123,136,169],"clarify":[9],"the":[10,15,20,22,57,62,71,112,114,128,141,164,206],"onset":[11,58],"and":[12,42,79,93,104,149,162,188],"course":[13],"of":[14,19,26,82,116,131,154,180],"disease.":[16],"In":[17],"50%":[18],"cases,":[21],"first":[23,174],"subjective":[24],"signs":[25],"disease":[27,207],"recorded":[29],"at":[30],"age":[31,115],"30":[32],"50":[34],"years.":[35,182],"A":[36,201],"large":[37,152],"variation":[38],"was,":[39],"however,":[40],"observed,":[41],"some":[43],"even":[45],"recalled":[46],"symptoms":[47,155],"as":[48,50,59],"early":[49],"in":[51,91,100],"childhood.":[52],"About":[53],"one":[54],"third":[55],"described":[56,64],"sudden,":[60],"whereas":[61],"rest":[63],"an":[65,177],"insidious":[66],"deterioration.":[67],"Keratoconjunctivitis":[68],"sicca":[69],"was":[70,86,173,208],"most":[72,119],"frequent":[73],"debut":[74],"symptom,":[75],"followed":[76],"by":[77],"xerostomia":[78],"weariness.":[80],"Regardless":[81],"age,":[83],"extreme":[84],"weariness":[85],"a":[87,137],"major":[88],"problem.":[89],"Pain":[90],"joints":[92],"muscles":[94],"tended":[95,107],"be":[97,109,158,170],"more":[98,110,125],"severe":[99,111],"younger":[101],"patients;":[102],"ocular":[103],"oral":[105],"problems":[106],"higher":[113],"debut.":[117],"Finally,":[118],"eventually":[121],"came":[122],"have":[124],"or":[126,160],"less":[127],"same":[129],"complex":[130],"symptoms,":[132],"which":[133],"could":[134,156],"lead":[135],"devastating":[138],"condition":[139],"affecting":[140],"not":[143,167],"only":[144],"physically":[145],"but":[146],"also":[147],"psychically":[148],"socially.":[150],"The":[151],"variety":[153],"easily":[157],"overlooked":[159],"misinterpreted,":[161],"because":[163],"did":[166],"appear":[168],"ill,":[171],"diagnosis":[172],"established":[175],"after":[176],"average":[178],"period":[179],"nine":[181],"Most":[183],"used":[185],"artificial":[186],"tears,":[187],"obtained":[189],"significantly":[190],"greater":[191],"benefit":[192],"from":[193,197],"this":[194],"remedy":[195],"than":[196],"all":[198],"other":[199],"drugs.":[200],"certain":[202],"familial":[203],"disposition":[204],"towards":[205],"found.":[209]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}