{"id":"https://openalex.org/W8933082","doi":null,"title":"Headspace - SPME as a screening system for yeast metabolic compounds: a case study","display_name":"Headspace - SPME as a screening system for yeast metabolic compounds: a case study","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W8933082","mag":"8933082"},"language":"en","primary_location":{"id":"pmh:oai:repositorium.sdum.uminho.pt:1822/8453","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1822/8453","pdf_url":"http://hdl.handle.net/1822/8453","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference paper"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1822/8453","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001958608","display_name":"Margarida Isabel Barros Coelho Martins","orcid":"https://orcid.org/0000-0002-4979-7634","observed_orcids":["https://orcid.org/0000-0002-4979-7634"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margarida Isabel Barros Coelho Martins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4979-7634","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060670302","display_name":"Mariana Henriques","orcid":"https://orcid.org/0000-0003-0317-4877","observed_orcids":["https://orcid.org/0000-0003-0317-4877","https://orcid.org/0009-0007-3597-9000","https://orcid.org/0009-0009-2090-449X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mariana Henriques","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0317-4877","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029481092","display_name":"Joana Azeredo","orcid":"https://orcid.org/0000-0002-5180-7133","observed_orcids":["https://orcid.org/0000-0002-5180-7133"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joana Azeredo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5180-7133","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103610231","display_name":"Ros\u00e1rio Oliveira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99682543","display_name":"University of Minho","ror":"https://ror.org/037wpkx04","country_code":"PT","type":"education","lineage":["https://openalex.org/I99682543"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ros\u00e1rio Oliveira","raw_affiliation_strings":["University of MInho"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of MInho","institution_ids":["https://openalex.org/I99682543"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10750","display_name":"Fermentation and Sensory Analysis","score":0.1459999978542328,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.026000000536441803,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/higher-alcohols","display_name":"higher alcohols","score":0.9390000104904175},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9829999804496765},{"id":"https://openalex.org/keywords/candida-dubliniensis","display_name":"Candida dubliniensis","score":1.0},{"id":"https://openalex.org/keywords/yeast-metabolism","display_name":"yeast metabolism","score":0.6809999942779541},{"id":"https://openalex.org/keywords/amino-acid-catabolism","display_name":"amino acid catabolism","score":0.9570000171661377},{"id":"https://openalex.org/keywords/leucine-catabolism","display_name":"leucine catabolism","score":0.8939999938011169},{"id":"https://openalex.org/keywords/phenylalanine-catabolism","display_name":"phenylalanine catabolism","score":1.0},{"id":"https://openalex.org/keywords/isoamyl-alcohol","display_name":"isoamyl alcohol","score":0.9869999885559082},{"id":"https://openalex.org/keywords/2-phenylethanol","display_name":"2-phenylethanol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/volatile-compounds","display_name":"volatile compounds","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C2776452521","wikidata":"https://www.wikidata.org/wiki/Q223101","display_name":"Isoamyl alcohol","level":3,"score":0.8118343353271484},{"id":"https://openalex.org/C13984183","wikidata":"https://www.wikidata.org/wiki/Q751627","display_name":"Fusel alcohol","level":3,"score":0.7916947603225708},{"id":"https://openalex.org/C2776445003","wikidata":"https://www.wikidata.org/wiki/Q3247005","display_name":"Candida dubliniensis","level":4,"score":0.7899677157402039},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7280185222625732},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7155435681343079},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.6516932845115662},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.46400371193885803},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.43166303634643555},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.3731224536895752},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.19413375854492188}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repositorium.sdum.uminho.pt:1822/8453","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1822/8453","pdf_url":"http://hdl.handle.net/1822/8453","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference paper"},{"id":"pmh:oai:repositorium.uminho.pt:1822/8453","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1822/8453","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference paper"},{"id":"mag:8933082","doi":null,"is_oa":false,"landing_page_url":"https://repositorium.sdum.uminho.pt/bitstream/1822/8453/1/Martins%5b1%5d.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repositorium.sdum.uminho.pt:1822/8453","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1822/8453","pdf_url":"http://hdl.handle.net/1822/8453","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference paper"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W8933082.pdf","grobid_xml":"https://content.openalex.org/works/W8933082.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1968060184","https://openalex.org/W1971966881","https://openalex.org/W1974053922","https://openalex.org/W2027695745","https://openalex.org/W2052738585","https://openalex.org/W2062128947","https://openalex.org/W2091508025","https://openalex.org/W2124144946","https://openalex.org/W2131404785","https://openalex.org/W2133337044","https://openalex.org/W2144677145","https://openalex.org/W2162551694","https://openalex.org/W2164904971"],"related_works":["https://openalex.org/W1988150408","https://openalex.org/W2013487226","https://openalex.org/W915110038","https://openalex.org/W7056142989","https://openalex.org/W1028222732","https://openalex.org/W2599322216","https://openalex.org/W1982870497","https://openalex.org/W2795458864","https://openalex.org/W2266189099","https://openalex.org/W2032568126"],"abstract_inverted_index":{"Aim:":[0],"This":[1,163],"study":[2],"aimed":[3],"to":[4,21,83,165],"identify":[5],"and":[6,18,35,55,103,109,123,127,142,153,157,159],"quantify":[7],"the":[8,13,26,85,116,119,130,139,171],"fusel":[9],"alcohols":[10,38],"secreted":[11],"by":[12],"opportunistic":[14],"yeasts":[15,47],"Candida":[16,19],"albicans":[17,102],"dubliniensis":[20,105],"further":[22],"get":[23],"insights":[24],"into":[25],"amino":[27,120],"acid":[28],"catabolism":[29,117],"of":[30,46,57,88,115,118,129,144,174],"those":[31],"two":[32],"organisms.":[33],"Methods":[34],"Results:":[36],"Fusel":[37],"were":[39],"screened":[40],"in":[41,49],"cell":[42],"-":[43,62,68,74,78],"free":[44],"supernatants":[45],"cultivated":[48],"RPMI":[50],"medium.":[51],"For":[52],"simultaneous":[53,140],"identification":[54,141],"quantification":[56,143],"these":[58],"alcohols,":[59],"a":[60,167],"Headspace":[61],"Solid":[63],"Phase":[64],"Micro":[65],"Extraction":[66],"(HS":[67],"SPME)":[69],"coupled":[70],"with":[71],"gas":[72],"chromatography":[73],"mass":[75],"spectrometry":[76],"(GC":[77],"MS)":[79],"methodology,":[80],"previously":[81],"developed":[82],"analyse":[84],"volatile":[86],"composition":[87],"fruits,":[89],"was":[90],"followed":[91],"(Coelho":[92],"et":[93],"al.":[94],"2006).":[95],"Results":[96],"obtained":[97],"show":[98],"that":[99],"both":[100],"C.":[101,104],"produced":[106],"isoamyl":[107],"alcohol":[108],"2-":[110],"phenylethanol,":[111],"end":[112],"\u2013":[113,134],"products":[114],"acids":[121],"leucine":[122],"phenylalanine,":[124],"respectively.":[125],"Significance":[126],"Impact":[128],"study:":[131],"The":[132],"HS":[133],"SPME":[135],"used":[136],"herein":[137],"allows":[138],"compounds,":[145],"requires":[146],"small":[147],"sample":[148],"volume,":[149],"has":[150],"high":[151],"sensitivity":[152],"reproducibility,":[154],"is":[155,160],"simple":[156],"rapid":[158],"solvent":[161],"free.":[162],"revealed":[164],"be":[166],"powerful":[168],"tool":[169],"for":[170],"screening":[172],"system":[173],"yeast":[175],"metabolic":[176],"compounds.":[177]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}