{"id":"https://openalex.org/W89291466","doi":"https://doi.org/10.17712/1658-3183.1955","title":"Intracranial calcifications, microcephaly, and seizure. If not congenital infection, what could it be?","display_name":"Intracranial calcifications, microcephaly, and seizure. If not congenital infection, what could it be?","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W89291466","doi":"https://doi.org/10.17712/1658-3183.1955","mag":"89291466","pmid":"https://pubmed.ncbi.nlm.nih.gov/22772931"},"language":"en","primary_location":{"id":"doi:10.17712/1658-3183.1955","doi":"https://doi.org/10.17712/1658-3183.1955","is_oa":false,"landing_page_url":"https://doi.org/10.17712/1658-3183.1955","pdf_url":null,"source":{"id":"https://openalex.org/S2754291465","display_name":"Neurosciences","issn_l":"1319-6138","issn":["1319-6138","1658-3183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319314","host_organization_name":"Riyadh Military Hospital","host_organization_lineage":["https://openalex.org/P4310319314"],"host_organization_lineage_names":["Riyadh Military Hospital"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059328280","display_name":"Wafaa Eyaid","orcid":"https://orcid.org/0000-0003-3983-2309","observed_orcids":["https://orcid.org/0000-0003-3983-2309","https://orcid.org/0000-0003-3442-7136"]},"institutions":[{"id":"https://openalex.org/I185203018","display_name":"King Saud bin Abdulaziz University for Health Sciences","ror":"https://ror.org/0149jvn88","country_code":"SA","type":"education","lineage":["https://openalex.org/I185203018"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Wafaa Eyaid","raw_affiliation_strings":["Department of Pediatrics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia. eyaidw@ngha.med.sa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia. eyaidw@ngha.med.sa","institution_ids":["https://openalex.org/I185203018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091911332","display_name":"Ruqaiah Altassan","orcid":"https://orcid.org/0000-0003-0146-8169","observed_orcids":["https://orcid.org/0000-0003-0146-8169"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruqaiah S. Al-Tassan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5028703207","display_name":"Doha M. Al-Nouri","orcid":"https://orcid.org/0000-0002-1230-1471","observed_orcids":["https://orcid.org/0000-0002-1230-1471"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Doha M. Al-Nouri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4476,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.61072639,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"17","issue":"3","first_page":"248","last_page":"252"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":0.6035000085830688,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":0.6035000085830688,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12924","display_name":"Dermatological and Skeletal Disorders","score":0.09780000150203705,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.07500000298023224,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intracranial-calcification","display_name":"intracranial calcification","score":0.9929999709129333},{"id":"https://openalex.org/keywords/microcephaly","display_name":"microcephaly","score":0.9919999837875366},{"id":"https://openalex.org/keywords/seizures","display_name":"seizures","score":0.8989999890327454},{"id":"https://openalex.org/keywords/congenital-infection","display_name":"congenital infection","score":0.8870000243186951},{"id":"https://openalex.org/keywords/toxoplasmosis","display_name":"toxoplasmosis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/cytomegalovirus","display_name":"cytomegalovirus","score":0.9779999852180481},{"id":"https://openalex.org/keywords/torch-infections","display_name":"TORCH infections","score":0.6819999814033508},{"id":"https://openalex.org/keywords/calcium-homeostasis","display_name":"calcium homeostasis","score":0.906000018119812},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C2776395126","wikidata":"https://www.wikidata.org/wiki/Q431643","display_name":"Microcephaly","level":2,"score":0.8657270669937134},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6888086795806885},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.6497696042060852},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5663066506385803},{"id":"https://openalex.org/C2777732132","wikidata":"https://www.wikidata.org/wiki/Q6946","display_name":"Cytomegalovirus","level":5,"score":0.5214442610740662},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.49191784858703613},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.4688207805156708},{"id":"https://openalex.org/C2778062946","wikidata":"https://www.wikidata.org/wiki/Q154878","display_name":"Toxoplasmosis","level":2,"score":0.4638146758079529},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.446901798248291},{"id":"https://openalex.org/C3020343245","wikidata":"https://www.wikidata.org/wiki/Q154878","display_name":"Congenital toxoplasmosis","level":4,"score":0.42715984582901},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27031221985816956},{"id":"https://openalex.org/C2778128430","wikidata":"https://www.wikidata.org/wiki/Q131003","display_name":"Toxoplasma gondii","level":3,"score":0.13953956961631775},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.12833312153816223},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.1228327751159668},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.08624434471130371},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.0814967155456543},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001927","descriptor_name":"Brain Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005192","descriptor_name":"Family Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008831","descriptor_name":"Microcephaly","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008831","descriptor_name":"Microcephaly","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D015898","descriptor_name":"Tomography Scanners, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.17712/1658-3183.1955","doi":"https://doi.org/10.17712/1658-3183.1955","is_oa":false,"landing_page_url":"https://doi.org/10.17712/1658-3183.1955","pdf_url":null,"source":{"id":"https://openalex.org/S2754291465","display_name":"Neurosciences","issn_l":"1319-6138","issn":["1319-6138","1658-3183"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","poland-40","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319314","host_organization_name":"Riyadh Military Hospital","host_organization_lineage":["https://openalex.org/P4310319314"],"host_organization_lineage_names":["Riyadh Military Hospital"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosciences","raw_type":"journal-article"},{"id":"pmid:22772931","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22772931","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosciences (Riyadh, Saudi Arabia)","raw_type":"Case Reports"},{"id":"mag:2327373489","doi":null,"is_oa":false,"landing_page_url":"http://www.neurosciencesjournal.org/PDFFILES/Jul12/Intracranial20110350.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:89291466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22772931","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1995604667","https://openalex.org/W2019678790","https://openalex.org/W2028665378","https://openalex.org/W2093042038","https://openalex.org/W2169189116","https://openalex.org/W2183134024"],"related_works":["https://openalex.org/W1977432769","https://openalex.org/W2091289861","https://openalex.org/W2315165286","https://openalex.org/W3041040485","https://openalex.org/W1964539055","https://openalex.org/W1984234594","https://openalex.org/W2085452990","https://openalex.org/W2040619984","https://openalex.org/W2028665378","https://openalex.org/W2116219739"],"abstract_inverted_index":{"Intracranial":[0],"calcification":[1,24],"has":[2],"a":[3],"variety":[4],"of":[5,40,46],"etiologies;":[6],"among":[7],"those":[8],"are":[9,25,33,53],"environmental":[10,19],"and":[11,30,51],"metabolic":[12],"disturbances":[13],"involving":[14],"calcium":[15],"homeostasis.":[16],"The":[17],"main":[18],"factors":[20],"resulting":[21],"in":[22,43],"intracranial":[23],"congenital":[26,41,66],"infections":[27],"with":[28],"toxoplasmosis,":[29],"cytomegalovirus.":[31],"There":[32],"increasing":[34],"reports":[35],"on":[36],"cases":[37,55],"showing":[38],"pictures":[39],"infection":[42],"the":[44,59],"absence":[45],"confirmative":[47],"positive":[48],"TORCH":[49],"screen,":[50],"there":[52],"many":[54],"reported":[56],"worldwide":[57],"sharing":[58],"same":[60],"presentation":[61],"labeled":[62],"as":[63],"autosomal":[64],"recessive":[65],"infection-like":[67],"syndrome":[68,71],"or":[69],"pseudo-TORCH":[70],"(OMIM":[72],"600158).":[73]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}