{"id":"https://openalex.org/W89021096","doi":"https://doi.org/10.24546/81005043","title":"N-terminal pro-brain natriuretic peptide levels in monochorionic diamniotic twins with twin-to-twin transfusion syndrome treated by fetoscopic laser photocoagulation.","display_name":"N-terminal pro-brain natriuretic peptide levels in monochorionic diamniotic twins with twin-to-twin transfusion syndrome treated by fetoscopic laser photocoagulation.","publication_year":2013,"publication_date":"2013-04-17","ids":{"openalex":"https://openalex.org/W89021096","doi":"https://doi.org/10.24546/81005043","mag":"89021096","pmid":"https://pubmed.ncbi.nlm.nih.gov/23756660"},"language":"en","primary_location":{"id":"pmid:23756660","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23756660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Kobe journal of medical sciences","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://da.lib.kobe-u.ac.jp/da/kernel/81005043/81005043.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054269216","display_name":"Kazumichi Fujioka","orcid":"https://orcid.org/0000-0002-9913-6447","observed_orcids":["https://orcid.org/0000-0002-9913-6447"]},"institutions":[{"id":"https://openalex.org/I4210125091","display_name":"Kobe Children's Hospital","ror":"https://ror.org/03jd3cd78","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125091"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazumichi Fujioka","raw_affiliation_strings":["Department of Neonatology, Hyogo Prefectural Kobe Children's Hospital Perinatal Center, Kobe 654-0081, Japan. fujiokak@med.kobe-u.ac.jp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Hyogo Prefectural Kobe Children's Hospital Perinatal Center, Kobe 654-0081, Japan. fujiokak@med.kobe-u.ac.jp","institution_ids":["https://openalex.org/I4210125091"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110115990","display_name":"Hitomi Sakai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hitomi Sakai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018058878","display_name":"Satoshi A. Tanaka","orcid":"https://orcid.org/0000-0003-4606-1522","observed_orcids":["https://orcid.org/0000-0003-4606-1522"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satoshi Tanaka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074245566","display_name":"Sota Iwatani","orcid":"https://orcid.org/0000-0002-2871-4000","observed_orcids":["https://orcid.org/0000-0002-2871-4000"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sota Iwatani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004446104","display_name":"Keiko Wada","orcid":"https://orcid.org/0000-0002-5467-8592","observed_orcids":["https://orcid.org/0000-0002-5467-8592"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keiko Wada","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112870949","display_name":"Masami Mizobuchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masami Mizobuchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080839651","display_name":"Seiji Yoshimoto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seiji Yoshimoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040096679","display_name":"Hideto Nakao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hideto Nakao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9314,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.76668769,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"59","issue":"1","first_page":"E28","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/twin-to-twin-transfusion-syndrome","display_name":"twin-twin transfusion syndrome","score":0.996999979019165},{"id":"https://openalex.org/keywords/monochorionic-diamniotic-twins","display_name":"monochorionic diamniotic twins","score":0.9779999852180481},{"id":"https://openalex.org/keywords/fetoscopic-laser-photocoagulation","display_name":"fetoscopic laser photocoagulation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.902999997138977},{"id":"https://openalex.org/keywords/cardiac-dysfunction","display_name":"cardiac dysfunction","score":0.652999997138977},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.7559999823570251},{"id":"https://openalex.org/keywords/perinatal-outcomes","display_name":"perinatal outcomes","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.74932461977005},{"id":"https://openalex.org/C2778853074","wikidata":"https://www.wikidata.org/wiki/Q6901425","display_name":"Monochorionic twins","level":4,"score":0.6887393593788147},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.6351625323295593},{"id":"https://openalex.org/C2909147877","wikidata":"https://www.wikidata.org/wiki/Q1409160","display_name":"Twin Twin Transfusion Syndrome","level":4,"score":0.6163316369056702},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.5812227725982666},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4577454924583435},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.32969093322753906},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.32252204418182373},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3219754695892334},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3061697483062744},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.10266146063804626},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08102646470069885},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005330","descriptor_name":"Fetofetal Transfusion","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005330","descriptor_name":"Fetofetal Transfusion","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005332","descriptor_name":"Fetoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014430","descriptor_name":"Twins, Monozygotic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017075","descriptor_name":"Laser Coagulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020097","descriptor_name":"Natriuretic Peptide, Brain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmid:23756660","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23756660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Kobe journal of medical sciences","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01257:0001675284","doi":"https://doi.org/10.24546/81005043","is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.14094/81005043","pdf_url":"https://da.lib.kobe-u.ac.jp/da/kernel/81005043/81005043.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Kobe journal of the medical sciences","raw_type":"departmental bulletin paper"},{"id":"pmh:oai:da.lib.kobe-u.ac.jp:20.500.14094/81005043","doi":"https://doi.org/10.24546/81005043","is_oa":true,"landing_page_url":"https://doi.org/10.24546/81005043","pdf_url":null,"source":{"id":"https://openalex.org/S4306401924","display_name":"Kobe University Repository Kernel (Kobe University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I65837984","host_organization_name":"Kobe University","host_organization_lineage":["https://openalex.org/I65837984"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Kobe journal of the medical sciences\u300059(1), 28-35","raw_type":"departmental bulletin paper"},{"id":"mag:89021096","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23756660","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01257:0001675284","doi":"https://doi.org/10.24546/81005043","is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.14094/81005043","pdf_url":"https://da.lib.kobe-u.ac.jp/da/kernel/81005043/81005043.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Kobe journal of the medical sciences","raw_type":"departmental bulletin paper"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W89021096.pdf","grobid_xml":"https://content.openalex.org/works/W89021096.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1511170570","https://openalex.org/W1973170872","https://openalex.org/W1990260157","https://openalex.org/W2000259574","https://openalex.org/W2014041775","https://openalex.org/W2019253521","https://openalex.org/W2026575732","https://openalex.org/W2028665554","https://openalex.org/W2034998166","https://openalex.org/W2057963867","https://openalex.org/W2061342516","https://openalex.org/W2075038930","https://openalex.org/W2078119798","https://openalex.org/W2089260966","https://openalex.org/W2091586680","https://openalex.org/W2092258296","https://openalex.org/W2102169261","https://openalex.org/W2102353085","https://openalex.org/W2118204392","https://openalex.org/W2119498517","https://openalex.org/W2136396259","https://openalex.org/W2137927062","https://openalex.org/W2151314694","https://openalex.org/W2157374745","https://openalex.org/W2325987598"],"related_works":["https://openalex.org/W2061342516","https://openalex.org/W4407164482","https://openalex.org/W4285588237","https://openalex.org/W2977308405","https://openalex.org/W2754579605","https://openalex.org/W2126839825","https://openalex.org/W4417441859","https://openalex.org/W7165046395","https://openalex.org/W2791751008","https://openalex.org/W1995041374"],"abstract_inverted_index":{"Twin-to-twin":[0],"transfusion":[1],"syndrome":[2],"(TTTS)":[3],"affects":[4],"15%":[5],"of":[6,46,67,203],"monochorionic":[7],"diamniotic":[8],"(MD)":[9],"twin":[10,105,126],"pregnancies,":[11],"and":[12,51,116,142,155,205],"is":[13,41,52],"associated":[14],"with":[15,57,96,99,107,138,211,228],"adverse":[16],"perinatal":[17],"outcome.":[18],"Recently,":[19],"fetoscopic":[20],"laser":[21],"photocoagulation":[22],"(FLP)":[23],"has":[24],"been":[25],"widely":[26],"accepted":[27],"as":[28],"the":[29,65,77,162,168,180,185],"most":[30],"definitive":[31],"therapy":[32],"to":[33,86,110],"treat":[34],"TTTS.":[35,58],"N-terminal":[36],"pro-brain":[37],"natriuretic":[38],"peptide":[39],"(NT-proBNP)":[40],"a":[42],"powerful":[43],"diagnostic":[44],"marker":[45],"cardiac":[47,71],"dysfunction":[48],"in":[49,54,73,93,121,161,167,179,184,225,234],"neonates,":[50],"elevated":[53],"MD":[55,94,104,125,226],"twins":[56,95,134,144,227],"However,":[59],"there":[60],"are":[61,223],"no":[62],"reports":[63],"assessing":[64],"effect":[66],"FLP":[68,100,139,149,163,181,231],"on":[69],"neonatal":[70],"overload":[72],"TTTS":[74,97,108,229],"by":[75],"measuring":[76],"serum":[78,88,200,218],"NT-proBNP":[79,89,172,201,219],"levels":[80,90,173,202,220],"at":[81,91,174,221],"birth.":[82],"Here,":[83],"we":[84],"aimed":[85],"compare":[87],"birth":[92,175,222],"treated":[98],"or":[101],"not.":[102],"Twelve":[103],"pairs":[106,127],"admitted":[109],"our":[111],"center":[112],"between":[113],"October":[114],"2007":[115],"September":[117],"2012":[118],"were":[119,128,158,176,208],"enrolled":[120],"this":[122],"study.":[123],"The":[124,199],"separated":[129],"into":[130],"two":[131],"groups:":[132],"seven":[133],"(12":[135],"newborn":[136,146],"infants)":[137,147],"(FLP":[140],"group)":[141],"five":[143],"(nine":[145],"without":[148,236],"(non-FLP":[150],"group).":[151],"Gestational":[152],"age,":[153],"birthweight,":[154],"Apgar":[156],"scores":[157],"significantly":[159,177,209],"higher":[160],"group":[164,182,187],"than":[165,183,233],"that":[166],"non-FLP":[169,186],"group.":[170],"Serum":[171],"lower":[178,224],"[1425":[188],"pg/ml":[189,194],"(range,":[190,195],"466-9560)":[191],"vs.":[192],"29900":[193],"7300-77900),":[196],"respectively;":[197],"p=0.0003].":[198],"larger":[204],"smaller":[206],"co-twins":[207],"correlated":[210],"each":[212],"other":[213],"(r=0.750;":[214],"p=0.026).":[215],"In":[216],"conclusion,":[217],"after":[230],"treatment":[232],"those":[235],"FLP.":[237]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}