{"id":"https://openalex.org/W88005284","doi":null,"title":"Statistical Physics of Water in Hydrophobic Nano-Confinement and at Proteins Interfaces","display_name":"Statistical Physics of Water in Hydrophobic Nano-Confinement and at Proteins Interfaces","publication_year":2013,"publication_date":"2013-07-19","ids":{"openalex":"https://openalex.org/W88005284","mag":"88005284"},"language":"en","primary_location":{"id":"pmh:oai:dnet:tdr_________::832a4964e2bfa8b2fdb6d131ba76cf05","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10803/120095","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10803/120095","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019459851","display_name":"Valentino Bianco","orcid":"https://orcid.org/0000-0003-3844-6406","observed_orcids":["https://orcid.org/0000-0003-3844-6406"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Valentino Bianco","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3844-6406","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5019459851"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10474","display_name":"Material Dynamics and Properties","score":0.6919000148773193,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10474","display_name":"Material Dynamics and Properties","score":0.6919000148773193,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12202","display_name":"nanoparticles nucleation surface interactions","score":0.260699987411499,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10591","display_name":"Theoretical and Computational Physics","score":0.028999999165534973,"subfield":{"id":"https://openalex.org/subfields/3104","display_name":"Condensed Matter Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/water-anomalies","display_name":"water anomalies","score":0.4449999928474426},{"id":"https://openalex.org/keywords/liquid-liquid-critical-point","display_name":"liquid-liquid critical point","score":0.875},{"id":"https://openalex.org/keywords/supercooled-water","display_name":"supercooled water","score":0.9319999814033508},{"id":"https://openalex.org/keywords/hydrophobic-interface","display_name":"hydrophobic interface","score":0.9139999747276306},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.3799999952316284},{"id":"https://openalex.org/keywords/coarse-grained-water-model","display_name":"coarse-grained water model","score":0.7400000095367432},{"id":"https://openalex.org/keywords/widom-line","display_name":"Widom line","score":0.7789999842643738},{"id":"https://openalex.org/keywords/liquid-liquid-phase-transition","display_name":"liquid-liquid phase transition","score":0.781000018119812},{"id":"https://openalex.org/keywords/percolation","display_name":"percolation","score":0.859000027179718},{"id":"https://openalex.org/keywords/ising-universality-class","display_name":"Ising universality class","score":0.8880000114440918},{"id":"https://openalex.org/keywords/protein-stability","display_name":"protein stability","score":0.8059999942779541},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.6380000114440918},{"id":"https://openalex.org/keywords/hydration-shell","display_name":"hydration shell","score":0.746999979019165},{"id":"https://openalex.org/keywords/hydrophobic-polymers","display_name":"hydrophobic polymers","score":0.6930000185966492},{"id":"https://openalex.org/keywords/pressure-denaturation","display_name":"pressure denaturation","score":0.5879999995231628},{"id":"https://openalex.org/keywords/cold-denaturation","display_name":"cold denaturation","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C85906118","wikidata":"https://www.wikidata.org/wiki/Q186693","display_name":"Phase diagram","level":3,"score":0.7311129570007324},{"id":"https://openalex.org/C112964491","wikidata":"https://www.wikidata.org/wiki/Q213659","display_name":"Supercooling","level":2,"score":0.7188413143157959},{"id":"https://openalex.org/C196298200","wikidata":"https://www.wikidata.org/wiki/Q577705","display_name":"Critical point (mathematics)","level":2,"score":0.6157456040382385},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.525846540927887},{"id":"https://openalex.org/C149288129","wikidata":"https://www.wikidata.org/wiki/Q185357","display_name":"Phase transition","level":2,"score":0.5025715827941895},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.4676757752895355},{"id":"https://openalex.org/C51329190","wikidata":"https://www.wikidata.org/wiki/Q1076349","display_name":"Ising model","level":2,"score":0.4616623520851135},{"id":"https://openalex.org/C119049451","wikidata":"https://www.wikidata.org/wiki/Q3318070","display_name":"Water model","level":3,"score":0.4562053680419922},{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.4235302209854126},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.41614097356796265},{"id":"https://openalex.org/C203036418","wikidata":"https://www.wikidata.org/wiki/Q284256","display_name":"Crystallization","level":2,"score":0.4141276776790619},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.4133450984954834},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.3806245028972626},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.3267168700695038},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16688677668571472},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.13932406902313232},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.10809153318405151},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:dnet:tdr_________::832a4964e2bfa8b2fdb6d131ba76cf05","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10803/120095","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:diposit.ub.edu:2445/45263","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2445/45263","pdf_url":"http://hdl.handle.net/10803/120095","source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tesis Doctorals - Departament - F\u00edsica Fonamental","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:www.tdx.cat:10803/120095","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10803/120095","pdf_url":null,"source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:88005284","doi":null,"is_oa":false,"landing_page_url":"http://diposit.ub.edu/dspace/bitstream/2445/45263/1/VALENTINO_BIANCO_THESIS.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306531624","display_name":"TDX (Tesis Doctorals en Xarxa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:diposit.ub.edu:2445/45263","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2445/45263","pdf_url":"http://hdl.handle.net/10803/120095","source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Tesis Doctorals - Departament - F\u00edsica Fonamental","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W88005284.pdf","grobid_xml":"https://content.openalex.org/works/W88005284.grobid-xml"},"referenced_works_count":230,"referenced_works":["https://openalex.org/W154742896","https://openalex.org/W1485019793","https://openalex.org/W1513206095","https://openalex.org/W1513720422","https://openalex.org/W1528929242","https://openalex.org/W1533569014","https://openalex.org/W1540380506","https://openalex.org/W1547580029","https://openalex.org/W1571663278","https://openalex.org/W1590167836","https://openalex.org/W1605182374","https://openalex.org/W1774151066","https://openalex.org/W1964852724","https://openalex.org/W1965555277","https://openalex.org/W1966014233","https://openalex.org/W1966056310","https://openalex.org/W1966230467","https://openalex.org/W1966863093","https://openalex.org/W1967118940","https://openalex.org/W1967959168","https://openalex.org/W1967994973","https://openalex.org/W1968481066","https://openalex.org/W1969334945","https://openalex.org/W1969620541","https://openalex.org/W1969631151","https://openalex.org/W1969758109","https://openalex.org/W1971256354","https://openalex.org/W1971416527","https://openalex.org/W1971705040","https://openalex.org/W1971771286","https://openalex.org/W1972702143","https://openalex.org/W1972999494","https://openalex.org/W1973649881","https://openalex.org/W1974137193","https://openalex.org/W1974847537","https://openalex.org/W1975526552","https://openalex.org/W1976302622","https://openalex.org/W1977258623","https://openalex.org/W1977410206","https://openalex.org/W1978636319","https://openalex.org/W1979165618","https://openalex.org/W1979189297","https://openalex.org/W1979778132","https://openalex.org/W1983023402","https://openalex.org/W1984527736","https://openalex.org/W1985309676","https://openalex.org/W1985384647","https://openalex.org/W1986633249","https://openalex.org/W1986984748","https://openalex.org/W1989609481","https://openalex.org/W1990601110","https://openalex.org/W1990623696","https://openalex.org/W1990989967","https://openalex.org/W1991723190","https://openalex.org/W1992210899","https://openalex.org/W1992382438","https://openalex.org/W1993299482","https://openalex.org/W1996203962","https://openalex.org/W1996610180","https://openalex.org/W1996784674","https://openalex.org/W2000215623","https://openalex.org/W2000733905","https://openalex.org/W2002168752","https://openalex.org/W2003509039","https://openalex.org/W2004593878","https://openalex.org/W2006130628","https://openalex.org/W2006152156","https://openalex.org/W2007395959","https://openalex.org/W2007673127","https://openalex.org/W2008131887","https://openalex.org/W2010168488","https://openalex.org/W2011447313","https://openalex.org/W2012325954","https://openalex.org/W2013700935","https://openalex.org/W2014476086","https://openalex.org/W2014554332","https://openalex.org/W2015374133","https://openalex.org/W2017859076","https://openalex.org/W2018673012","https://openalex.org/W2019145327","https://openalex.org/W2019357664","https://openalex.org/W2019576395","https://openalex.org/W2019701019","https://openalex.org/W2020357924","https://openalex.org/W2021063796","https://openalex.org/W2021093276","https://openalex.org/W2021168853","https://openalex.org/W2021233158","https://openalex.org/W2021540131","https://openalex.org/W2021863374","https://openalex.org/W2022731012","https://openalex.org/W2023167709","https://openalex.org/W2023187371","https://openalex.org/W2023995653","https://openalex.org/W2025145657","https://openalex.org/W2026338660","https://openalex.org/W2026446160","https://openalex.org/W2026764199","https://openalex.org/W2027384625","https://openalex.org/W2027766146","https://openalex.org/W2028329272","https://openalex.org/W2029075368","https://openalex.org/W2029375222","https://openalex.org/W2030524340","https://openalex.org/W2031277168","https://openalex.org/W2031981257","https://openalex.org/W2032787141","https://openalex.org/W2034603867","https://openalex.org/W2035710720","https://openalex.org/W2037139490","https://openalex.org/W2037193428","https://openalex.org/W2037842899","https://openalex.org/W2038142139","https://openalex.org/W2038470880","https://openalex.org/W2041871841","https://openalex.org/W2042106902","https://openalex.org/W2042546922","https://openalex.org/W2043697182","https://openalex.org/W2044962560","https://openalex.org/W2045008347","https://openalex.org/W2045235789","https://openalex.org/W2046013318","https://openalex.org/W2046917943","https://openalex.org/W2047291302","https://openalex.org/W2047486534","https://openalex.org/W2048147222","https://openalex.org/W2048549270","https://openalex.org/W2049060108","https://openalex.org/W2049218783","https://openalex.org/W2049600134","https://openalex.org/W2049603070","https://openalex.org/W2051039246","https://openalex.org/W2051045984","https://openalex.org/W2051466520","https://openalex.org/W2051765324","https://openalex.org/W2052797255","https://openalex.org/W2053545079","https://openalex.org/W2053841828","https://openalex.org/W2056316433","https://openalex.org/W2056331471","https://openalex.org/W2056760934","https://openalex.org/W2057183009","https://openalex.org/W2057246411","https://openalex.org/W2057431120","https://openalex.org/W2059236771","https://openalex.org/W2060444602","https://openalex.org/W2062078129","https://openalex.org/W2062828002","https://openalex.org/W2063651676","https://openalex.org/W2063665017","https://openalex.org/W2065765419","https://openalex.org/W2065958034","https://openalex.org/W2067061708","https://openalex.org/W2067773385","https://openalex.org/W2069950286","https://openalex.org/W2070206101","https://openalex.org/W2072180796","https://openalex.org/W2074306137","https://openalex.org/W2074788452","https://openalex.org/W2074958926","https://openalex.org/W2076056973","https://openalex.org/W2077437403","https://openalex.org/W2078143253","https://openalex.org/W2079276884","https://openalex.org/W2081591455","https://openalex.org/W2082017430","https://openalex.org/W2082723205","https://openalex.org/W2085081102","https://openalex.org/W2086295275","https://openalex.org/W2086852158","https://openalex.org/W2087579950","https://openalex.org/W2087980400","https://openalex.org/W2091396661","https://openalex.org/W2092805442","https://openalex.org/W2095302421","https://openalex.org/W2095963307","https://openalex.org/W2096633859","https://openalex.org/W2097688224","https://openalex.org/W2097693311","https://openalex.org/W2098958953","https://openalex.org/W2104754918","https://openalex.org/W2108023227","https://openalex.org/W2109475825","https://openalex.org/W2111402465","https://openalex.org/W2113697506","https://openalex.org/W2114689007","https://openalex.org/W2117611274","https://openalex.org/W2118314550","https://openalex.org/W2122122704","https://openalex.org/W2128389934","https://openalex.org/W2129478124","https://openalex.org/W2131754023","https://openalex.org/W2132102738","https://openalex.org/W2133266834","https://openalex.org/W2133806434","https://openalex.org/W2134301789","https://openalex.org/W2135862662","https://openalex.org/W2136528212","https://openalex.org/W2137352412","https://openalex.org/W2142538803","https://openalex.org/W2143114323","https://openalex.org/W2143464363","https://openalex.org/W2145814047","https://openalex.org/W2147953091","https://openalex.org/W2148712714","https://openalex.org/W2150900482","https://openalex.org/W2152855567","https://openalex.org/W2155292749","https://openalex.org/W2158232357","https://openalex.org/W2158801277","https://openalex.org/W2159009162","https://openalex.org/W2167678601","https://openalex.org/W2167785274","https://openalex.org/W2212085734","https://openalex.org/W2315656104","https://openalex.org/W2316853019","https://openalex.org/W2340457491","https://openalex.org/W2346327787","https://openalex.org/W2485036724","https://openalex.org/W2486629449","https://openalex.org/W2490343224","https://openalex.org/W2588270902","https://openalex.org/W2783504562","https://openalex.org/W3003303647","https://openalex.org/W3015358064","https://openalex.org/W3098951805","https://openalex.org/W3107148387","https://openalex.org/W3112972845","https://openalex.org/W3113109455","https://openalex.org/W4231846841"],"related_works":["https://openalex.org/W2030765316","https://openalex.org/W2950951957","https://openalex.org/W7100537371","https://openalex.org/W2133760196","https://openalex.org/W4297683842","https://openalex.org/W2072180796","https://openalex.org/W7095802302","https://openalex.org/W2941386883","https://openalex.org/W7095457222","https://openalex.org/W2956525884"],"abstract_inverted_index":{"Water":[0,24,365],"is":[1,64,82,117,371],"commonly":[2],"associated":[3],"with":[4,241,295,428,478],"life.":[5],"This":[6],"substance":[7],"affects":[8],"the":[9,46,50,54,58,70,74,88,103,115,118,129,135,157,168,188,191,198,210,214,225,228,236,242,260,270,275,286,288,291,296,310,313,318,327,336,348,368,375,379,390,399,403,407,410,413,423,436,440,447,455,472],"living":[10],"beings":[11],"in":[12,45,80,148,167,177,194,197,326,344,398,422,445,460],"countless":[13],"aspects":[14],"and":[15,125,152,175,274,304,317,363,409,459,465,482],"length":[16,220],"scales,":[17],"ranging":[18],"from":[19],"molecular":[20],"biology":[21],"to":[22,65,86,101,373,435,470,480],"climatology.":[23],"exhibits":[25],"a":[26,38,41,83,98,160,178,232,252,280,339,353,393,475],"long":[27],"series":[28],"of":[29,40,49,57,61,73,78,90,106,114,120,128,138,159,162,190,216,218,224,235,245,255,262,264,267,290,312,315,320,329,338,352,392,412,442,457,474],"anomalous":[30,243],"behaviors.":[31],"These":[32,247],"anomalies":[33,314],"can":[34],"be":[35,374],"rationalized":[36],"as":[37],"consequence":[39],"second":[42],"critical":[43,180,298],"point":[44,181],"supercooled":[47,62,139],"region":[48,342],"liquid":[51,173],"phase.":[52],"Nevertheless,":[53],"large":[55,202,233],"part":[56],"phase":[59,136,165,271],"diagram":[60,137],"water":[63,79,107,140,256,316,444],"date":[66],"experimentally":[67],"inaccessible":[68],"for":[69,206,347,378],"inevitable":[71],"crystallization":[72,89],"bulk":[75],"liquid.":[76],"Confinement":[77],"nano-structures":[81],"possible":[84],"way":[85],"prevent":[87],"molecules.":[91],"\\n\\n\\t\\t\\t\\t":[92,300],"In":[93],"this":[94,358,386],"thesis":[95],"we":[96,212,230,278,388,416],"present":[97],"coarse-grain":[99,400],"model":[100,116,193],"describe":[102],"physical":[104],"behavior":[105,366],"at":[108,309,367,406],"hydrophobic":[109,143,395],"interfaces.":[110],"The":[111,183,301],"essential":[112],"feature":[113],"description":[119,254],"water-water":[121,404],"interaction":[122,405],"via":[123],"directional":[124],"cooperative":[126],"components":[127],"hydrogen":[130],"bond":[131],"(HB).":[132],"We":[133,451],"explore":[134],"nano-confined":[141],"between":[142],"walls.":[144],"Our":[145,432],"results,":[146],"grounded":[147],"statistical":[149],"physics":[150,456],"methods":[151],"Monte":[153],"Carlo":[154],"simulations,":[155],"show":[156,452],"presence":[158],"line":[161,273,277],"first":[163],"order":[164],"transition":[166,272],"temperature-pressure":[169,345,424],"plane":[170,346],"separating":[171],"two":[172,195],"phases":[174],"ending":[176],"liquid-liquid":[179],"(LLCP).":[182],"LLCP":[184,211,229,287,322],"universality":[185],"class":[186],"approaches":[187],"one":[189],"Ising":[192,297],"dimensions":[196],"thermodynamic":[199,237,333],"limit,":[200],"while":[201],"deviations":[203],"are":[204,249,308,468],"observed":[205],"strong":[207],"confinement.":[208],"Below":[209],"find":[213,231,417],"locus":[215],"maxima":[217],"correlation":[219],"(the":[221],"Widom":[222,276],"line)":[223],"system.":[226],"Near":[227],"increase":[234],"response":[238],"functions":[239],"consistent":[240,427],"behaviors":[244],"water.\\n\\n\\t\\t\\t\\t":[246],"predictions":[248],"confirmed":[250],"by":[251],"percolation":[253,292],"molecules":[257],"based":[258],"on":[259,385],"definition":[261],"cluster":[263,283],"correlated":[265],"degrees":[266],"freedom.":[268],"Along":[269],"recover":[279],"power":[281],"law":[282],"distribution.":[284],"At":[285],"scaling":[289],"quantities":[293],"agree":[294],"exponents.":[299],"density,":[302],"energy":[303],"entropy":[305,466],"fluctuations":[306,467],"that":[307,454],"base":[311],"existence":[319,337,473],"its":[321,462],"have":[323],"also":[324],"consequences":[325],"context":[328],"protein":[330,369,420,449,476],"stability.":[331],"General":[332],"prediction":[334],"asserts":[335],"close":[340],"stability":[341],"(SR)":[343],"native":[349,448],"folded":[350,394],"state":[351],"protein.":[354],"Experimental":[355],"evidences":[356],"support":[357],"theory":[359],"showing":[360],"hot-,":[361],"cold-":[362],"pressure-denaturation.":[364],"interface":[370,408],"expected":[372],"driving":[376],"force":[377],"folding-unfolding":[380],"process.":[381],"To":[382],"shed":[383],"light":[384],"mechanism":[387],"study":[389],"SR":[391,421,477],"polymer":[396],"solvated":[397],"water.":[401],"Tuning":[402],"density":[411,464],"hydration":[414,443],"shell":[415],"an":[418],"elliptic":[419],"plane,":[425],"qualitatively":[426],"available":[429],"experimental":[430],"data.":[431],"work":[433],"contributes":[434],"ongoing":[437],"debate":[438],"about":[439],"role":[441],"stabilizing":[446],"state.":[450],"here":[453],"water,":[458],"particular":[461],"energy,":[463],"sufficient":[469],"rationalize":[471],"respect":[479],"temperature":[481],"pressure.":[483]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}