{"id":"https://openalex.org/W866146237","doi":null,"title":"Overview and implications of obstructive sleep apnoea.","display_name":"Overview and implications of obstructive sleep apnoea.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W866146237","mag":"866146237","pmid":"https://pubmed.ncbi.nlm.nih.gov/18610698"},"language":"en","primary_location":{"id":"pmid:18610698","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18610698","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of chest diseases & allied sciences","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102049065","display_name":"Hanish Sharma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Hanish Sharma","raw_affiliation_strings":["Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039967820","display_name":"Sunil Sharma","orcid":"https://orcid.org/0000-0002-1308-5985","observed_orcids":["https://orcid.org/0000-0002-1308-5985","https://orcid.org/0000-0001-9612-0231"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S K Sharma","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"50","issue":"1","first_page":"137","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cpap-therapy","display_name":"CPAP therapy","score":0.7850000262260437},{"id":"https://openalex.org/keywords/oral-appliances","display_name":"oral appliances","score":0.777999997138977},{"id":"https://openalex.org/keywords/upper-airway-surgery","display_name":"upper airway surgery","score":0.9959999918937683},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.6230000257492065},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.593999981880188},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9470000267028809},{"id":"https://openalex.org/keywords/procoagulant-state","display_name":"procoagulant state","score":0.8989999890327454},{"id":"https://openalex.org/keywords/excessive-daytime-sleepiness","display_name":"excessive daytime sleepiness","score":0.8560000061988831},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8859999775886536},{"id":"https://openalex.org/keywords/low-cost-diagnostics","display_name":"low-cost diagnostics","score":0.5759999752044678},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.6510000228881836},{"id":"https://openalex.org/keywords/developing-countries","display_name":"developing countries","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.952180027961731},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.7404342889785767},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.660617470741272},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.648786723613739},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.5736300945281982},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.4452023208141327},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.4262950122356415},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17273586988449097},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:18610698","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18610698","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of chest diseases & allied sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W32893675","https://openalex.org/W38628731","https://openalex.org/W44398835","https://openalex.org/W49897421","https://openalex.org/W117904160","https://openalex.org/W1714259827","https://openalex.org/W1791691867","https://openalex.org/W1970596096","https://openalex.org/W1972862048","https://openalex.org/W1972918993","https://openalex.org/W1975382102","https://openalex.org/W1988111570","https://openalex.org/W1994263114","https://openalex.org/W1994817894","https://openalex.org/W1995621262","https://openalex.org/W1996692474","https://openalex.org/W2002041877","https://openalex.org/W2002316925","https://openalex.org/W2007885276","https://openalex.org/W2010359746","https://openalex.org/W2012882995","https://openalex.org/W2015619070","https://openalex.org/W2016294629","https://openalex.org/W2016819916","https://openalex.org/W2025248470","https://openalex.org/W2026091188","https://openalex.org/W2026171747","https://openalex.org/W2028123491","https://openalex.org/W2031374244","https://openalex.org/W2033770922","https://openalex.org/W2037464054","https://openalex.org/W2046139892","https://openalex.org/W2046716347","https://openalex.org/W2049117384","https://openalex.org/W2054593321","https://openalex.org/W2055090290","https://openalex.org/W2055884503","https://openalex.org/W2057023498","https://openalex.org/W2060293824","https://openalex.org/W2063135200","https://openalex.org/W2064616510","https://openalex.org/W2068250277","https://openalex.org/W2074302897","https://openalex.org/W2078259015","https://openalex.org/W2078385819","https://openalex.org/W2079556915","https://openalex.org/W2082533403","https://openalex.org/W2083565033","https://openalex.org/W2086261438","https://openalex.org/W2093457132","https://openalex.org/W2093818735","https://openalex.org/W2094173817","https://openalex.org/W2105613623","https://openalex.org/W2106061071","https://openalex.org/W2110980488","https://openalex.org/W2112656829","https://openalex.org/W2113283606","https://openalex.org/W2113638222","https://openalex.org/W2113765726","https://openalex.org/W2114718215","https://openalex.org/W2123633020","https://openalex.org/W2124052130","https://openalex.org/W2126776837","https://openalex.org/W2127341006","https://openalex.org/W2130340796","https://openalex.org/W2135708450","https://openalex.org/W2136431713","https://openalex.org/W2137130170","https://openalex.org/W2137330341","https://openalex.org/W2139356364","https://openalex.org/W2139826323","https://openalex.org/W2142674616","https://openalex.org/W2151147308","https://openalex.org/W2152837221","https://openalex.org/W2158366956","https://openalex.org/W2160420088","https://openalex.org/W2162208719","https://openalex.org/W2162747978","https://openalex.org/W2163979524","https://openalex.org/W2165011379","https://openalex.org/W2168227200","https://openalex.org/W2171175214","https://openalex.org/W2188580780","https://openalex.org/W2199579349","https://openalex.org/W2201946268","https://openalex.org/W2319970884","https://openalex.org/W2333343699","https://openalex.org/W2335449614","https://openalex.org/W2400483924","https://openalex.org/W2411968148","https://openalex.org/W2413439520","https://openalex.org/W2418395917","https://openalex.org/W2525235483","https://openalex.org/W4247301605"],"related_works":["https://openalex.org/W3210146488","https://openalex.org/W4400504150","https://openalex.org/W2156431490","https://openalex.org/W2968137547","https://openalex.org/W2135100612","https://openalex.org/W2023454994","https://openalex.org/W4254677408","https://openalex.org/W2765049939","https://openalex.org/W2585521352","https://openalex.org/W4415147041"],"abstract_inverted_index":{"Obstructive":[0],"sleep":[1,37],"apnoea":[2],"(OSA)":[3],"is":[4,44,171],"a":[5,45,85,109,191],"leading":[6],"public":[7],"health":[8],"problem":[9],"both":[10],"in":[11,78,139],"the":[12,33,95,106,122,129,166,183],"developed":[13],"and":[14,23,51,54,67,84,97,148,161],"developing":[15,31],"nations.":[16],"However,":[17,111],"awareness":[18],"regarding":[19,105],"diagnostic":[20,53],"options,":[21],"management":[22],"consequences":[24],"of":[25,72,76,100,108,113,131,156,185],"untreated":[26],"OSA":[27,59,77,101],"remains":[28,121,143],"inadequate.":[29],"In":[30],"nations,":[32],"resources":[34],"for":[35,47],"adequate":[36],"medicine":[38],"facilities":[39],"are":[40,151,165],"scarce.":[41],"Therefore,":[42],"there":[43],"need":[46],"low":[48],"cost,":[49],"simple":[50],"accurate":[52],"therapeutic":[55],"modalities":[56],"exists.":[57],"Untreated":[58],"leads":[60],"to":[61,177],"excessive":[62],"daytime":[63],"sleepiness,":[64],"diminished":[65],"performance":[66],"an":[68],"overall":[69],"poor":[70],"quality":[71,130,184],"life.":[73],"The":[74],"role":[75],"promoting":[79],"insulin":[80],"resistance,":[81],"atherosclerosis,":[82],"hypertension":[83],"procoagulant":[86],"state":[87],"has":[88],"now":[89],"been":[90],"established.":[91],"Newer":[92,154],"insights":[93],"into":[94],"biochemical":[96],"genetic":[98],"mediators":[99],"have":[102],"raised":[103],"hopes":[104],"development":[107],"\"cure\".":[110],"as":[112,133,135,187,189],"now,":[114],"continuous":[115],"positive":[116],"airway":[117,163],"pressure":[118],"(CPAP)":[119],"therapy":[120],"first-line":[123],"treatment.":[124],"Though":[125],"its":[126],"use":[127,150,176],"improves":[128],"life":[132,186],"well":[134,188],"metabolic":[136],"derangements":[137],"observed":[138],"OSA,":[140],"patients'":[141,179],"acceptance":[142],"low.":[144],"Its":[145],"high":[146],"cost":[147],"long-term":[149],"also":[152],"cumbersome.":[153],"modes":[155],"delivering":[157],"CPAP,":[158],"oral":[159],"appliances":[160],"upper":[162],"surgery":[164],"other":[167],"options":[168],"available.":[169],"It":[170],"hoped":[172],"that":[173],"their":[174],"appropriate":[175],"increase":[178],"compliance":[180],"may":[181],"improve":[182],"provide":[190],"survival":[192],"benefit.":[193]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}