{"id":"https://openalex.org/W861099194","doi":null,"title":"Three proteins regulating integrin function - filamin, 14-3-3 and RIAM","display_name":"Three proteins regulating integrin function - filamin, 14-3-3 and RIAM","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W861099194","mag":"861099194"},"language":"en","primary_location":{"id":"pmh:oai:jyx.jyu.fi:123456789/37091","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","pdf_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081048434","display_name":"Heikki Takala","orcid":"https://orcid.org/0000-0003-2518-8583","observed_orcids":["https://orcid.org/0000-0003-2518-8583"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Heikki Takala","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2518-8583","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5081048434"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"232","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integrin-regulation","display_name":"integrin regulation","score":0.7519999742507935},{"id":"https://openalex.org/keywords/filamin-a","display_name":"filamin A","score":0.7739999890327454},{"id":"https://openalex.org/keywords/riam","display_name":"RIAM","score":0.9739999771118164},{"id":"https://openalex.org/keywords/rap1-gtpase","display_name":"Rap1 GTPase","score":0.7300000190734863},{"id":"https://openalex.org/keywords/talin","display_name":"talin","score":0.9789999723434448},{"id":"https://openalex.org/keywords/integrin-cytoplasmic-tail","display_name":"integrin cytoplasmic tail","score":0.7940000295639038},{"id":"https://openalex.org/keywords/integrin-activation","display_name":"integrin activation","score":0.5649999976158142},{"id":"https://openalex.org/keywords/inside-out-signaling","display_name":"inside-out signaling","score":0.6340000033378601},{"id":"https://openalex.org/keywords/ras-association-domain","display_name":"Ras association domain","score":0.8169999718666077},{"id":"https://openalex.org/keywords/ph-domain","display_name":"pleckstrin homology domain","score":0.9980000257492065},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.5230000019073486},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7269999980926514},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C20563397","wikidata":"https://www.wikidata.org/wiki/Q410803","display_name":"Filamin","level":4,"score":0.9231508374214172},{"id":"https://openalex.org/C195687474","wikidata":"https://www.wikidata.org/wiki/Q409715","display_name":"Integrin","level":3,"score":0.8571482300758362},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6667078733444214},{"id":"https://openalex.org/C156585808","wikidata":"https://www.wikidata.org/wiki/Q18028043","display_name":"Integrin, beta 6","level":4,"score":0.549511730670929},{"id":"https://openalex.org/C171779818","wikidata":"https://www.wikidata.org/wiki/Q3799301","display_name":"Integrin alpha M","level":3,"score":0.45039740204811096},{"id":"https://openalex.org/C2776179587","wikidata":"https://www.wikidata.org/wiki/Q54461864","display_name":"Rap1","level":3,"score":0.43512314558029175},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.43445849418640137},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4055933356285095},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3851359486579895},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2830820083618164},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.27732276916503906},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2693432569503784},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2488131821155548},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.0785599946975708}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:jyx.jyu.fi:123456789/37091","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","pdf_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},{"id":"mag:861099194","doi":null,"is_oa":false,"landing_page_url":"https://jyx.jyu.fi/bitstream/123456789/37091/1/9789513945244.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764873975","display_name":"Jyv\u00e4skyl\u00e4 studies in biological and environmental science","issn_l":"1456-9701","issn":["1456-9701"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Jyv\u00e4skyl\u00e4 studies in biological and environmental science","raw_type":null}],"best_oa_location":{"id":"pmh:oai:jyx.jyu.fi:123456789/37091","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","pdf_url":"http://urn.fi/URN:ISBN:978-951-39-4524-4","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_db06"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320312347","display_name":"Ellen ja Artturi Nyyss\u00f6sen S\u00e4\u00e4ti\u00f6","ror":"https://ror.org/05t9r1624"},{"id":"https://openalex.org/F4320323168","display_name":"Jyv\u00e4skyl\u00e4n Yliopisto","ror":"https://ror.org/05n3dz165"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W861099194.pdf","grobid_xml":"https://content.openalex.org/works/W861099194.grobid-xml"},"referenced_works_count":262,"referenced_works":["https://openalex.org/W119252893","https://openalex.org/W1460802340","https://openalex.org/W1493062728","https://openalex.org/W1500690807","https://openalex.org/W1500795239","https://openalex.org/W1526383449","https://openalex.org/W1546886821","https://openalex.org/W1547653016","https://openalex.org/W1555730591","https://openalex.org/W1576773659","https://openalex.org/W1586593449","https://openalex.org/W1590619267","https://openalex.org/W1602267722","https://openalex.org/W1695152928","https://openalex.org/W1887623574","https://openalex.org/W1901040110","https://openalex.org/W1925800905","https://openalex.org/W1938388466","https://openalex.org/W1962628502","https://openalex.org/W1964681919","https://openalex.org/W1965862787","https://openalex.org/W1965871583","https://openalex.org/W1968339091","https://openalex.org/W1968710931","https://openalex.org/W1968815565","https://openalex.org/W1969419418","https://openalex.org/W1972470306","https://openalex.org/W1972516366","https://openalex.org/W1972849246","https://openalex.org/W1973800056","https://openalex.org/W1974043829","https://openalex.org/W1975024491","https://openalex.org/W1976389026","https://openalex.org/W1976796981","https://openalex.org/W1977257516","https://openalex.org/W1977426071","https://openalex.org/W1977602054","https://openalex.org/W1979331393","https://openalex.org/W1980948443","https://openalex.org/W1980973069","https://openalex.org/W1981368559","https://openalex.org/W1982280065","https://openalex.org/W1984297174","https://openalex.org/W1984347187","https://openalex.org/W1985432448","https://openalex.org/W1986476951","https://openalex.org/W1988472239","https://openalex.org/W1988692408","https://openalex.org/W1988822956","https://openalex.org/W1989949522","https://openalex.org/W1990283596","https://openalex.org/W1990425248","https://openalex.org/W1990883677","https://openalex.org/W1991011186","https://openalex.org/W1992283755","https://openalex.org/W1992437471","https://openalex.org/W1992733780","https://openalex.org/W1994331544","https://openalex.org/W1995553619","https://openalex.org/W1998089975","https://openalex.org/W1998539678","https://openalex.org/W2000247424","https://openalex.org/W2000681550","https://openalex.org/W2000843281","https://openalex.org/W2001640037","https://openalex.org/W2002590458","https://openalex.org/W2003111769","https://openalex.org/W2003698382","https://openalex.org/W2004032118","https://openalex.org/W2004542682","https://openalex.org/W2006217190","https://openalex.org/W2007096555","https://openalex.org/W2007869203","https://openalex.org/W2008067534","https://openalex.org/W2009080196","https://openalex.org/W2009702029","https://openalex.org/W2009793240","https://openalex.org/W2011372972","https://openalex.org/W2011739619","https://openalex.org/W2012470118","https://openalex.org/W2013452582","https://openalex.org/W2013672653","https://openalex.org/W2013841398","https://openalex.org/W2014653319","https://openalex.org/W2014886554","https://openalex.org/W2015341098","https://openalex.org/W2016129682","https://openalex.org/W2016614012","https://openalex.org/W2016715162","https://openalex.org/W2016775197","https://openalex.org/W2016952508","https://openalex.org/W2018237041","https://openalex.org/W2019326922","https://openalex.org/W2021053981","https://openalex.org/W2021856025","https://openalex.org/W2022161594","https://openalex.org/W2022664595","https://openalex.org/W2022851623","https://openalex.org/W2024923170","https://openalex.org/W2026132650","https://openalex.org/W2026804025","https://openalex.org/W2028170357","https://openalex.org/W2028305453","https://openalex.org/W2028740022","https://openalex.org/W2028890259","https://openalex.org/W2030282026","https://openalex.org/W2031261181","https://openalex.org/W2032348507","https://openalex.org/W2035293726","https://openalex.org/W2035913349","https://openalex.org/W2036107124","https://openalex.org/W2036286128","https://openalex.org/W2037419242","https://openalex.org/W2039159306","https://openalex.org/W2040095760","https://openalex.org/W2040379229","https://openalex.org/W2040880223","https://openalex.org/W2040936676","https://openalex.org/W2041534105","https://openalex.org/W2042570069","https://openalex.org/W2042639779","https://openalex.org/W2044694582","https://openalex.org/W2048059179","https://openalex.org/W2048127037","https://openalex.org/W2050054339","https://openalex.org/W2050476475","https://openalex.org/W2051238023","https://openalex.org/W2051580348","https://openalex.org/W2051903847","https://openalex.org/W2053519260","https://openalex.org/W2058437633","https://openalex.org/W2058624823","https://openalex.org/W2058843732","https://openalex.org/W2059324975","https://openalex.org/W2060136332","https://openalex.org/W2061168934","https://openalex.org/W2064198025","https://openalex.org/W2064818197","https://openalex.org/W2065497298","https://openalex.org/W2065869497","https://openalex.org/W2067092549","https://openalex.org/W2067202475","https://openalex.org/W2067386422","https://openalex.org/W2067836657","https://openalex.org/W2068992908","https://openalex.org/W2069552300","https://openalex.org/W2069576969","https://openalex.org/W2069820450","https://openalex.org/W2071075259","https://openalex.org/W2073118670","https://openalex.org/W2075973849","https://openalex.org/W2076366164","https://openalex.org/W2077145521","https://openalex.org/W2077237370","https://openalex.org/W2077590283","https://openalex.org/W2077895194","https://openalex.org/W2078673440","https://openalex.org/W2079001576","https://openalex.org/W2081121052","https://openalex.org/W2082526323","https://openalex.org/W2083063047","https://openalex.org/W2083100745","https://openalex.org/W2083240338","https://openalex.org/W2084302112","https://openalex.org/W2084822426","https://openalex.org/W2087129887","https://openalex.org/W2088495902","https://openalex.org/W2088544660","https://openalex.org/W2089364234","https://openalex.org/W2090404342","https://openalex.org/W2090659127","https://openalex.org/W2091119718","https://openalex.org/W2091521837","https://openalex.org/W2092447350","https://openalex.org/W2093873926","https://openalex.org/W2094469836","https://openalex.org/W2096563079","https://openalex.org/W2096873421","https://openalex.org/W2097139362","https://openalex.org/W2098438673","https://openalex.org/W2100326225","https://openalex.org/W2101244168","https://openalex.org/W2101346022","https://openalex.org/W2102674665","https://openalex.org/W2105183595","https://openalex.org/W2106256524","https://openalex.org/W2108496308","https://openalex.org/W2109137926","https://openalex.org/W2109319033","https://openalex.org/W2112319250","https://openalex.org/W2112611026","https://openalex.org/W2112981236","https://openalex.org/W2114213585","https://openalex.org/W2116317468","https://openalex.org/W2118758577","https://openalex.org/W2120832308","https://openalex.org/W2121278567","https://openalex.org/W2121781131","https://openalex.org/W2122209607","https://openalex.org/W2123122700","https://openalex.org/W2123235745","https://openalex.org/W2125070282","https://openalex.org/W2127170661","https://openalex.org/W2127369178","https://openalex.org/W2128494600","https://openalex.org/W2129917438","https://openalex.org/W2130123417","https://openalex.org/W2131309206","https://openalex.org/W2137326912","https://openalex.org/W2137732486","https://openalex.org/W2139691749","https://openalex.org/W2141089307","https://openalex.org/W2141288132","https://openalex.org/W2141643986","https://openalex.org/W2142111204","https://openalex.org/W2143523073","https://openalex.org/W2143554526","https://openalex.org/W2144687721","https://openalex.org/W2144859098","https://openalex.org/W2147898539","https://openalex.org/W2147922874","https://openalex.org/W2148016530","https://openalex.org/W2148377692","https://openalex.org/W2149667112","https://openalex.org/W2152204239","https://openalex.org/W2153870676","https://openalex.org/W2154909249","https://openalex.org/W2155894151","https://openalex.org/W2156293127","https://openalex.org/W2157012084","https://openalex.org/W2157330541","https://openalex.org/W2157809114","https://openalex.org/W2158600429","https://openalex.org/W2160658743","https://openalex.org/W2161033372","https://openalex.org/W2161648203","https://openalex.org/W2162005182","https://openalex.org/W2162589243","https://openalex.org/W2167744079","https://openalex.org/W2169767879","https://openalex.org/W2170812873","https://openalex.org/W2171667332","https://openalex.org/W2233114566","https://openalex.org/W2258622567","https://openalex.org/W2329321343","https://openalex.org/W2400803738","https://openalex.org/W2427875153","https://openalex.org/W2938408575","https://openalex.org/W3154083640","https://openalex.org/W3160888931","https://openalex.org/W3161523060","https://openalex.org/W3168177564","https://openalex.org/W3173004024","https://openalex.org/W3177029843","https://openalex.org/W3184419745","https://openalex.org/W3184684695","https://openalex.org/W3185818011","https://openalex.org/W4295677753","https://openalex.org/W4322388708","https://openalex.org/W4322388709","https://openalex.org/W7128520876","https://openalex.org/W7140249799"],"related_works":["https://openalex.org/W1538775453","https://openalex.org/W2169767879","https://openalex.org/W7066188932","https://openalex.org/W2086113284","https://openalex.org/W7095861022","https://openalex.org/W2569280839","https://openalex.org/W2413560965","https://openalex.org/W2288407771","https://openalex.org/W2619970483","https://openalex.org/W1983458493"],"abstract_inverted_index":{"4":[0],"(PDF)":[1],"Yhteenveto:":[2],"Kolme":[3],"integriinin":[4],"toimintaa":[5],"s\u00e4\u00e4telev\u00e4\u00e4":[6],"proteiinia":[7],"-filamiini,":[8],"14-3-3":[9,142,156,233,277],"ja":[10],"RIAM":[11],"Diss.Integrins":[12],"are":[13],"transmembrane":[14],"adhesion":[15,55],"receptors":[16],"important":[17,102],"in":[18,52,120,234],"cell":[19],"adhesion,":[20],"migration":[21],"and":[22,50,72,148,155,211],"survival.Integrin":[23],"activation":[24,136],"is":[25,62,97,128,139,176,250,274,280],"regulated":[26],"by":[27,33,65,141,165,276,282],"cytoplasmic":[28,37,42,54,123],"proteinprotein":[29],"interactions.Talin":[30],"activates":[31],"integrins":[32,83],"binding":[34,180,225,260,266,270,286],"to":[35,58,82,99,181,208,213,221,271],"integrin":[36,53,89,95,121,127,240],"tails.As":[38],"dozens":[39],"of":[40,108,125,151,191,198,227,232,267],"other":[41],"proteins":[43],"interact":[44],"with":[45,84,92,116,236],"integrins,":[46],"their":[47],"mutual":[48],"interactions":[49],"function":[51],"structures":[56],"have":[57],"be":[59,100,209],"carefully":[60],"regulated.This":[61],"achieved,":[63],"e.g.,":[64],"protein":[66,73],"recruitment,":[67],"competitive":[68],"binding,":[69],"alternative":[70],"splicing":[71],"phosphorylation.The":[74],"Rap1-GTP":[75],"interacting":[76],"adapter":[77],"molecule":[78],"(RIAM)":[79],"recruits":[80],"talin":[81,93,269],"Rap1":[85],"GTPase,":[86],"thereby":[87],"facilitating":[88],"activation.Filamins":[90],"compete":[91],"for":[94,103,178,188],"binding.This":[96],"expected":[98],"particularly":[101],"a":[104,114,131,160,166,196],"splice":[105],"variant-1":[106],"(var-1)":[107],"filamin":[109],"A":[110],"(FLNa)":[111],"that":[112,172,202],"lacks":[113,195],"segment":[115,197],"an":[117],"autoinhibitory":[118],"role":[119],"binding.The":[122],"tail":[124],"2":[126,239],"phosphorylated":[129,238],"on":[130,252,288],"threonine":[132],"residue":[133],"upon":[134],"inside-out":[135],"events,":[137],"which":[138,279],"accompanied":[140],"binding.In":[143],"this":[144,203,248],"thesis,":[145],"the":[146,173,179,184,189,192,224,237,244,253,265,272,283,289],"structural":[147],"functional":[149],"properties":[150,226],"RIAM,":[152],"FLNa":[153,259],"var-1":[154,194],"were":[157],"studied.RIAM":[158],"contains":[159],"Ras-association":[161],"(RA)":[162],"domain":[163,175,186,206,228],"followed":[164],"pleckstrin":[167],"homology":[168],"(PH)":[169],"domain.We":[170],"showed":[171,201],"RA":[174],"responsible":[177],"Rap1,":[182],"whereas":[183],"PH":[185],"accounts":[187],"stability":[190],"protein.FLNa":[193],"41":[199],"residues.We":[200],"absence":[204],"causes":[205],"19":[207],"unstructured":[210],"unable":[212],"bind":[214],"ligands,":[215],"but":[216,261],"it":[217],"does":[218,262],"not":[219,263],"seem":[220],"significantly":[222],"affect":[223,264],"21.The":[229],"crystal":[230],"structure":[231],"complex":[235],"peptide":[241],"reveals":[242],"at":[243],"atomic":[245],"level":[246],"how":[247],"interaction":[249],"dependent":[251],"phosphate":[254],"moiety.The":[255],"same":[256],"phosphorylation":[257],"abrogates":[258],"talin.However,":[268],"phosphopeptide":[273],"outcompeted":[275],",":[278],"explained":[281],"partially":[284],"overlapping":[285],"sites":[287],"integrin.":[290]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
