{"id":"https://openalex.org/W85950437","doi":null,"title":"Magnesium metabolism in chronic renal failure.","display_name":"Magnesium metabolism in chronic renal failure.","publication_year":1990,"publication_date":"1990-06-01","ids":{"openalex":"https://openalex.org/W85950437","mag":"85950437","pmid":"https://pubmed.ncbi.nlm.nih.gov/2133626"},"language":"en","primary_location":{"id":"pmid:2133626","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2133626","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnesium research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110452135","display_name":"Th. D. Mountokalakis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"T D Mountokalakis","raw_affiliation_strings":["Second Medical Department, Athens University, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Medical Department, Athens University, Greece","institution_ids":["https://openalex.org/I200777214"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110452135"],"corresponding_institution_ids":["https://openalex.org/I200777214"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.0132213,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"3","issue":"2","first_page":"121","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12280","display_name":"Magnesium in Health and Disease","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12280","display_name":"Magnesium in Health and Disease","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnesium-metabolism","display_name":"magnesium metabolism","score":0.996999979019165},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.8650000095367432},{"id":"https://openalex.org/keywords/magnesium-balance","display_name":"magnesium balance","score":0.7070000171661377},{"id":"https://openalex.org/keywords/urinary-magnesium-excretion","display_name":"urinary magnesium excretion","score":0.8610000014305115},{"id":"https://openalex.org/keywords/intestinal-magnesium-absorption","display_name":"intestinal magnesium absorption","score":0.8669999837875366},{"id":"https://openalex.org/keywords/vitamin-d-deficiency","display_name":"vitamin D deficiency","score":0.7990000247955322},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.8370000123977661},{"id":"https://openalex.org/keywords/continuous-ambulatory-peritoneal-dialysis","display_name":"continuous ambulatory peritoneal dialysis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/dialysate-magnesium","display_name":"dialysate magnesium","score":0.9179999828338623},{"id":"https://openalex.org/keywords/renal-osteodystrophy","display_name":"renal osteodystrophy","score":0.8560000061988831},{"id":"https://openalex.org/keywords/uremic-pruritus","display_name":"uremic pruritus","score":0.9169999957084656},{"id":"https://openalex.org/keywords/arterial-calcification","display_name":"arterial calcification","score":0.9509999752044678},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9480000138282776}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6094932556152344},{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.6094706058502197},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5932456851005554},{"id":"https://openalex.org/C2909406889","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Continuous ambulatory peritoneal dialysis","level":3,"score":0.5457068085670471},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5229295492172241},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.509353518486023},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.48542341589927673},{"id":"https://openalex.org/C2776699218","wikidata":"https://www.wikidata.org/wiki/Q822598","display_name":"Renal osteodystrophy","level":3,"score":0.44831234216690063},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.4296831488609314},{"id":"https://openalex.org/C161457703","wikidata":"https://www.wikidata.org/wiki/Q3317402","display_name":"Renal physiology","level":3,"score":0.42928335070610046},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.41522184014320374},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34664151072502136},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.2557523846626282},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007408","descriptor_name":"Intestinal Absorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D010531","descriptor_name":"Peritoneal Dialysis, Continuous Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2133626","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2133626","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Magnesium research","raw_type":"Journal Article"},{"id":"mag:85950437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2133626","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2155794381","https://openalex.org/W2792669568","https://openalex.org/W2075285533","https://openalex.org/W1544754104","https://openalex.org/W199202509","https://openalex.org/W2068173890","https://openalex.org/W2341687024","https://openalex.org/W7098782738","https://openalex.org/W2410911154","https://openalex.org/W2803459623"],"abstract_inverted_index":{"Renal":[0],"excretion":[1,40],"is":[2,32,79,100,160],"the":[3,10,54,58,72,109,131,138,142,154,161,166,170,178,190],"major":[4,155],"route":[5],"of":[6,22,57,71,120,130,134,144,157,163,180,192],"magnesium":[7,15,39,64,77,88,112,121,158,164,172],"elimination":[8],"from":[9],"body":[11],"and":[12,204],"a":[13,26,80,212],"positive":[14],"balance":[16,89,159],"would":[17],"be":[18,91,125],"expected":[19],"under":[20],"conditions":[21],"renal":[23,52,117,181,197,209],"insufficiency.":[24],"However,":[25,199],"compensatory":[27],"decrease":[28],"in":[29,50,68,74,96,165,169,195,208],"tubular":[30],"reabsorption":[31],"operating":[33],"to":[34,60,103,124,127,176,183,188,215],"maintain":[35],"an":[36,62],"adequate":[37],"urinary":[38],"even":[41,94],"when":[42,83],"glomerular":[43],"filtration":[44],"rates":[45],"are":[46,86],"very":[47],"low.":[48],"Nevertheless,":[49],"end-stage":[51],"disease,":[53],"limited":[55],"ability":[56],"kidney":[59],"excrete":[61],"increased":[63],"load":[65],"may":[66,90],"result":[67],"toxic":[69],"concentrations":[70],"ion":[73],"serum.":[75],"While":[76],"intoxication":[78],"real":[81],"hazard":[82],"magnesium-containing":[84],"drugs":[85],"given,":[87],"normal":[92],"or":[93,147,187],"decreased":[95,104],"uraemic":[97,185],"patients.":[98],"This":[99],"usually":[101],"due":[102],"dietary":[105],"intake":[106],"combined":[107],"with":[108],"impaired":[110],"intestinal":[111],"absorption":[113,122],"which":[114],"characterizes":[115],"chronic":[116,145,196],"failure.":[118],"Impairment":[119],"seems":[123],"related":[126],"deficient":[128],"synthesis":[129],"active":[132],"metabolite":[133],"vitamin":[135],"D":[136],"by":[137],"non-functioning":[139],"kidney.":[140],"Following":[141],"institution":[143],"haemodialysis":[146],"continuous":[148],"ambulatory":[149],"peritoneal":[150],"dialysis":[151],"(CAPD)":[152],"treatment,":[153],"determinant":[156],"concentration":[162],"dialysate.":[167],"Changes":[168],"dialysate":[171],"have":[173],"been":[174],"used":[175],"reduce":[177],"incidence":[179],"osteodystrophy,":[182],"alleviate":[184],"pruritus,":[186],"retard":[189],"development":[191],"arterial":[193],"calcification":[194],"disease.":[198],"uncertainty":[200],"about":[201],"magnesium,":[202],"calcium":[203],"parathyroid":[205],"hormone":[206],"relationships":[207],"failure":[210],"makes":[211],"reasoned":[213],"approach":[214],"such":[216],"manipulations":[217],"extremely":[218],"difficult.":[219]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}