{"id":"https://openalex.org/W856959898","doi":null,"title":"Retinal vascular changes and immune restoration in a cohort of HIV patients on highly active antiretroviral therapy","display_name":"Retinal vascular changes and immune restoration in a cohort of HIV patients on highly active antiretroviral therapy","publication_year":2014,"publication_date":"2014-04-30","ids":{"openalex":"https://openalex.org/W856959898","mag":"856959898"},"language":"en","primary_location":{"id":"mag:856959898","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2268180","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108562585","display_name":"Petrina Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]},{"id":"https://openalex.org/I4405257834","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4405257834"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Petrina Tan","raw_affiliation_strings":["Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685","https://openalex.org/I4405257834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014884788","display_name":"Ling Jun Li","orcid":"https://orcid.org/0000-0002-3628-1364","observed_orcids":["https://orcid.org/0000-0002-3628-1364"]},"institutions":[{"id":"https://openalex.org/I2799299286","display_name":"Singapore National Eye Center","ror":"https://ror.org/029nvrb94","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2799299286"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Ling Jun Li","raw_affiliation_strings":["Ophthalmology, Singapore Eye Research Institute, Singapore National Eye Centre,, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-3628-1364","affiliations":[{"raw_affiliation_string":"Ophthalmology, Singapore Eye Research Institute, Singapore National Eye Centre,, Singapore, Singapore","institution_ids":["https://openalex.org/I2799299286","https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014232998","display_name":"Owen Kim Hee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]},{"id":"https://openalex.org/I4405257834","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4405257834"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Owen Kim Hee","raw_affiliation_strings":["Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685","https://openalex.org/I4405257834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084913828","display_name":"Carol Yim-lui Cheung","orcid":"https://orcid.org/0000-0003-0869-859X","observed_orcids":["https://orcid.org/0000-0003-0869-859X"]},"institutions":[{"id":"https://openalex.org/I2799299286","display_name":"Singapore National Eye Center","ror":"https://ror.org/029nvrb94","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2799299286"]},{"id":"https://openalex.org/I4210116917","display_name":"Singapore Eye Research Institute","ror":"https://ror.org/02crz6e12","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4210116917"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Carol Y. Cheung","raw_affiliation_strings":["Ophthalmology, Singapore Eye Research Institute, Singapore National Eye Centre,, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, Singapore Eye Research Institute, Singapore National Eye Centre,, Singapore, Singapore","institution_ids":["https://openalex.org/I2799299286","https://openalex.org/I4210116917"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052634452","display_name":"Rupesh V. Agrawal","orcid":"https://orcid.org/0000-0002-6662-5850","observed_orcids":["https://orcid.org/0000-0002-6662-5850"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]},{"id":"https://openalex.org/I4405257834","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4405257834"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Rupesh Agrawal","raw_affiliation_strings":["Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-6662-5850","affiliations":[{"raw_affiliation_string":"Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685","https://openalex.org/I4405257834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111499768","display_name":"Tock Han Lim","orcid":"https://orcid.org/0000-0002-1821-0538","observed_orcids":["https://orcid.org/0000-0002-1821-0538"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]},{"id":"https://openalex.org/I4405257834","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4405257834"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Tock Han Lim","raw_affiliation_strings":["Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685","https://openalex.org/I4405257834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072258594","display_name":"Tien Yin Wong","orcid":"https://orcid.org/0000-0002-8448-1264","observed_orcids":["https://orcid.org/0000-0002-8448-1264"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Tien Yin Wong","raw_affiliation_strings":["Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore,, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-8448-1264","affiliations":[{"raw_affiliation_string":"Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore,, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091638065","display_name":"Stephen Charn Beng Teoh","orcid":"https://orcid.org/0000-0002-9359-9694","observed_orcids":["https://orcid.org/0000-0002-9359-9694"]},"institutions":[{"id":"https://openalex.org/I2802408685","display_name":"Tan Tock Seng Hospital","ror":"https://ror.org/032d59j24","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2802408685"]},{"id":"https://openalex.org/I4405257834","display_name":"National Healthcare Group","ror":"https://ror.org/05qkemg93","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I4405257834"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Stephen C. Teoh","raw_affiliation_strings":["Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-9359-9694","affiliations":[{"raw_affiliation_string":"Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore","institution_ids":["https://openalex.org/I2802408685","https://openalex.org/I4405257834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11984941,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"55","issue":"13","first_page":"2817","last_page":"2817"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.5351999998092651,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.5351999998092651,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12599","display_name":"Retinal and Optic Conditions","score":0.1234000027179718,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.0674000009894371,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-vessels","display_name":"retinal vasculature","score":0.7860000133514404},{"id":"https://openalex.org/keywords/immune-reconstitution","display_name":"immune reconstitution","score":0.7110000252723694},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.8420000076293945},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.9909999966621399},{"id":"https://openalex.org/keywords/hiv-associated-retinopathy","display_name":"HIV-associated retinopathy","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.738140344619751},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.736608624458313},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6388940215110779},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5921689867973328},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5093744993209839},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4764590561389923},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3547724783420563},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2963409423828125},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.2913898825645447},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.17577406764030457}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:856959898","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2268180","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.699999988079071,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2747710132","https://openalex.org/W2021589502","https://openalex.org/W812716076","https://openalex.org/W1180447173","https://openalex.org/W4210934701","https://openalex.org/W2516751288","https://openalex.org/W2742430533","https://openalex.org/W1190887796","https://openalex.org/W3139450916","https://openalex.org/W1609356640"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T17:25:34.749102","created_date":"2016-06-24T00:00:00"}