{"id":"https://openalex.org/W85078285","doi":"https://doi.org/10.3233/thc-2002-10105","title":"The area of the pressure \u2013 flow loop for assessment of arterial stenosis: A new index","display_name":"The area of the pressure \u2013 flow loop for assessment of arterial stenosis: A new index","publication_year":2002,"publication_date":"2002-02-07","ids":{"openalex":"https://openalex.org/W85078285","doi":"https://doi.org/10.3233/thc-2002-10105","mag":"85078285","pmid":"https://pubmed.ncbi.nlm.nih.gov/11847447"},"language":"en","primary_location":{"id":"doi:10.3233/thc-2002-10105","doi":"https://doi.org/10.3233/thc-2002-10105","is_oa":false,"landing_page_url":"https://doi.org/10.3233/thc-2002-10105","pdf_url":null,"source":{"id":"https://openalex.org/S2501230301","display_name":"Technology and Health Care","issn_l":"0928-7329","issn":["0928-7329","1878-7401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and Health Care","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014537300","display_name":"Zehava Ovadia\u2010Blechman","orcid":"https://orcid.org/0000-0002-7544-9705","observed_orcids":["https://orcid.org/0000-0002-7544-9705"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Zehava Ovadia-Blechman","raw_affiliation_strings":["Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel","institution_ids":["https://openalex.org/I16391192","https://openalex.org/I2799810450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052244637","display_name":"Shmuel Einav","orcid":"https://orcid.org/0000-0002-6344-8203","observed_orcids":["https://orcid.org/0000-0002-6344-8203"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Shmuel Einav","raw_affiliation_strings":["Department of Biomedical Engineering, Tel-Aviv University, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tel-Aviv University, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027366702","display_name":"Uri Zaretsky","orcid":"https://orcid.org/0000-0002-2905-6222","observed_orcids":["https://orcid.org/0000-0002-2905-6222"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Uri Zaretsky","raw_affiliation_strings":["Department of Biomedical Engineering, Tel-Aviv University, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Tel-Aviv University, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David Castel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"David Castel","raw_affiliation_strings":["Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel","institution_ids":["https://openalex.org/I16391192","https://openalex.org/I2799810450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103541820","display_name":"Eran Toledo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Eran Toledo","raw_affiliation_strings":["The Abramson Center for Medical Physics, Sackler Faculty of Exact Sciences, Tel-Aviv University, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Abramson Center for Medical Physics, Sackler Faculty of Exact Sciences, Tel-Aviv University, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108486029","display_name":"Michael Eldar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Michael Eldar","raw_affiliation_strings":["Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neufeld Cardiac Research Institute, Tel-Aviv University, Sheba Medical Center, Israel","institution_ids":["https://openalex.org/I16391192","https://openalex.org/I2799810450"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052244637"],"corresponding_institution_ids":["https://openalex.org/I16391192"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.2114,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.58852759,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"10","issue":"1","first_page":"39","last_page":"56"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.7773000001907349,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.7773000001907349,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.09880000352859497,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.07400000095367432,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arterial-stenosis","display_name":"arterial stenosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/stenosis-severity-assessment","display_name":"stenosis severity assessment","score":0.8700000047683716},{"id":"https://openalex.org/keywords/longitudinal-waves","display_name":"longitudinal waves","score":0.8410000205039978},{"id":"https://openalex.org/keywords/vascular-grafts","display_name":"vascular grafts","score":0.6259999871253967},{"id":"https://openalex.org/keywords/arterial-elasticity","display_name":"arterial elasticity","score":0.9179999828338623},{"id":"https://openalex.org/keywords/noninvasive-hemodynamic-measurement","display_name":"noninvasive hemodynamic measurement","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.785818338394165},{"id":"https://openalex.org/C2781460075","wikidata":"https://www.wikidata.org/wiki/Q1399332","display_name":"Compliance (psychology)","level":2,"score":0.49609383940696716},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.48347312211990356},{"id":"https://openalex.org/C184670325","wikidata":"https://www.wikidata.org/wiki/Q512604","display_name":"Loop (graph theory)","level":2,"score":0.47012436389923096},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46584638953208923},{"id":"https://openalex.org/C121854251","wikidata":"https://www.wikidata.org/wiki/Q62932","display_name":"Elasticity (physics)","level":2,"score":0.41629672050476074},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4088563323020935},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3971061110496521},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.35463428497314453},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3449455499649048},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.3399720788002014},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21766719222068787},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.09505319595336914},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001157","descriptor_name":"Arterial Occlusive Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001157","descriptor_name":"Arterial Occlusive Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003935","descriptor_name":"Diagnostic Techniques, Cardiovascular","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004548","descriptor_name":"Elasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005263","descriptor_name":"Femoral Artery","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012212","descriptor_name":"Rheology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3233/thc-2002-10105","doi":"https://doi.org/10.3233/thc-2002-10105","is_oa":false,"landing_page_url":"https://doi.org/10.3233/thc-2002-10105","pdf_url":null,"source":{"id":"https://openalex.org/S2501230301","display_name":"Technology and Health Care","issn_l":"0928-7329","issn":["0928-7329","1878-7401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and Health Care","raw_type":"journal-article"},{"id":"pmid:11847447","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11847447","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Technology and health care : official journal of the European Society for Engineering and Medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1971429532","https://openalex.org/W1974595603","https://openalex.org/W1977026704","https://openalex.org/W1980899074","https://openalex.org/W1981542111","https://openalex.org/W1987039651","https://openalex.org/W1990885923","https://openalex.org/W1994374856","https://openalex.org/W1998868705","https://openalex.org/W2004432004","https://openalex.org/W2030133216","https://openalex.org/W2033483382","https://openalex.org/W2037734595","https://openalex.org/W2049562314","https://openalex.org/W2049926385","https://openalex.org/W2055124598","https://openalex.org/W2063619042","https://openalex.org/W2069032248","https://openalex.org/W2069483243","https://openalex.org/W2083647281","https://openalex.org/W2093359389","https://openalex.org/W2110959935","https://openalex.org/W2143724599","https://openalex.org/W2163235023","https://openalex.org/W2221447153","https://openalex.org/W2277954652","https://openalex.org/W2320707747"],"related_works":["https://openalex.org/W2128717356","https://openalex.org/W2114438299","https://openalex.org/W6997285558","https://openalex.org/W2110959935","https://openalex.org/W1423065476","https://openalex.org/W2145267861","https://openalex.org/W2011534376","https://openalex.org/W2146278238","https://openalex.org/W7221994104","https://openalex.org/W4299732811"],"abstract_inverted_index":{"This":[0,133],"study":[1],"describes":[2],"a":[3,31],"novel":[4],"method":[5],"for":[6],"assessing":[7],"stenotic":[8],"severity,":[9],"based":[10],"on":[11],"simultaneous":[12],"pressure":[13],"and":[14,19,26,29,44,66,111,122,141,145],"flow":[15,20,55],"wave":[16,53,56],"measurements.":[17],"Pressure":[18,35,52],"measurements":[21],"were":[22,37,69,95],"performed":[23],"in":[24,30,98],"latex":[25],"rubber":[27],"tubes,":[28],"clinically-used":[32],"vascular":[33],"graft.":[34],"waves":[36],"recorded":[38],"at":[39,45],"several":[40],"degrees":[41,80],"of":[42,72,81,107,150],"stenosis":[43,82,104,112],"different":[46],"distances":[47],"proximal":[48],"to":[49,124,139,146],"the":[50,127,148,151],"stenosis.":[51],"versus":[54],"was":[57,88,120],"plotted.":[58],"Internal":[59],"pressure-flow":[60],"loop":[61,64],"area":[62],"(PFLA),":[63],"slope":[65],"pressure-axis":[67],"intercept":[68],"calculated.":[70],"Values":[71],"these":[73],"three":[74],"indices":[75],"significantly":[76,137],"increased":[77],"with":[78,126],"increasing":[79],"P":[83],"<":[84],"0.001).":[85],"Similar":[86],"phenomenon":[87],"observed":[89],"during":[90],"in-vivo":[91],"experiments.":[92],"Polynomial":[93],"functions":[94],"fitted,":[96],"resulting":[97],"an":[99],"excellent":[100],"PFLA":[101],"variable/":[102],"percent":[103],"correlation,":[105],"independent":[106],"distance":[108],"between":[109],"sensor":[110],"(R2":[113],">":[114,131],"0.96).":[115],"In":[116],"addition,":[117],"tube":[118],"compliance":[119],"measured":[121],"found":[123],"correlate":[125],"polynomial":[128],"coefficients":[129],"(/R/":[130],"0.9).":[132],"innovative":[134],"approach":[135],"could":[136],"contribute":[138],"detecting":[140],"evaluating":[142],"arterial":[143],"stenoses,":[144],"characterize":[147],"elasticity":[149],"artery.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}