{"id":"https://openalex.org/W846713276","doi":null,"title":"MBD2 regulates TH17 differentiation by controlling the homeostasis of T-bet/Hlx axis through binding to methylated CpG DNA","display_name":"MBD2 regulates TH17 differentiation by controlling the homeostasis of T-bet/Hlx axis through binding to methylated CpG DNA","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W846713276","mag":"846713276"},"language":"en","primary_location":{"id":"mag:846713276","doi":null,"is_oa":false,"landing_page_url":"http://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/163645/Details","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Autoimmunity","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010451432","display_name":"Jinchen Zhong","orcid":"https://orcid.org/0000-0003-0901-4321","observed_orcids":["https://orcid.org/0000-0003-0901-4321"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinchen Zhong","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0901-4321","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Qing Yu","orcid":"https://orcid.org/0000-0002-5818-0564","observed_orcids":["https://orcid.org/0000-0002-5818-0564"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing Yu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5818-0564","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017575108","display_name":"Peng Yang","orcid":"https://orcid.org/0000-0002-9724-7936","observed_orcids":["https://orcid.org/0000-0002-9724-7936"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peng Yang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9724-7936","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101671066","display_name":"Le\u2010jian He","orcid":"https://orcid.org/0009-0003-6109-1807","observed_orcids":["https://orcid.org/0009-0003-6109-1807"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Le\u2010jian He","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051712163","display_name":"Johnny Fang","orcid":"https://orcid.org/0000-0002-4553-3148","observed_orcids":["https://orcid.org/0000-0002-4553-3148"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johnny Fang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4553-3148","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101888207","display_name":"Yingfeng Tu","orcid":"https://orcid.org/0000-0002-8848-127X","observed_orcids":["https://orcid.org/0000-0002-8848-127X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yingfeng Tu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001765543","display_name":"Z Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Qian Lai","orcid":"https://orcid.org/0000-0002-4282-7757","observed_orcids":["https://orcid.org/0000-0002-4282-7757"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qian Lai","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4282-7757","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015277244","display_name":"Songyang Zhang","orcid":"https://orcid.org/0009-0005-8612-9765","observed_orcids":["https://orcid.org/0009-0005-8612-9765"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Songyang Zhang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-8612-9765","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Xinglong Rao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinglong Rao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071950745","display_name":"M Kucsma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Kucsma","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005016605","display_name":"Piotr Jan Kraj","orcid":"https://orcid.org/0000-0003-2122-5105","observed_orcids":["https://orcid.org/0000-0003-2122-5105"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piotr Kraj","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2122-5105","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101090960","display_name":"J-F Xu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J-F Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062249120","display_name":"Fuxing Gong","orcid":"https://orcid.org/0000-0001-8119-8474","observed_orcids":["https://orcid.org/0000-0001-8119-8474"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fuxing Gong","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8119-8474","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101495085","display_name":"Jiarong Zhou","orcid":"https://orcid.org/0000-0002-5381-5751","observed_orcids":["https://orcid.org/0000-0002-5381-5751"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jiarong Zhou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5381-5751","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086212380","display_name":"Liangzhi Wen","orcid":"https://orcid.org/0000-0001-9999-2422","observed_orcids":["https://orcid.org/0000-0001-9999-2422"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liangzhi Wen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9999-2422","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064248322","display_name":"Decio Laks Eizirik","orcid":"https://orcid.org/0000-0003-2453-5889","observed_orcids":["https://orcid.org/0000-0003-2453-5889"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D\u00e9cio L. Eizirik","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2453-5889","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023953234","display_name":"Jinge Du","orcid":"https://orcid.org/0000-0001-7597-1723","observed_orcids":["https://orcid.org/0000-0001-7597-1723"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Du","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7597-1723","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081873313","display_name":"W Wang","orcid":"https://orcid.org/0000-0002-2962-4525","observed_orcids":["https://orcid.org/0000-0002-2962-4525"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108113333","display_name":"CY Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"CY Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5420,"currency":"USD","value_usd":5420},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03549002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.49459999799728394,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.49459999799728394,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.45750001072883606,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.023800000548362732,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mbd2","display_name":"MBD2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/th17-differentiation","display_name":"Th17 cell differentiation","score":0.8370000123977661},{"id":"https://openalex.org/keywords/t-bet","display_name":"T-bet","score":0.9800000190734863},{"id":"https://openalex.org/keywords/hlx","display_name":"HLX","score":0.9200000166893005},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cpg-methylation","display_name":"CpG methylation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/t-helper-cell-differentiation","display_name":"T helper cell differentiation","score":0.6460000276565552},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C140173407","wikidata":"https://www.wikidata.org/wiki/Q1138358","display_name":"CpG site","level":5,"score":0.6370618939399719},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.5976773500442505},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5313506722450256},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.44155776500701904},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4412570297718048},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38574090600013733},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3475170135498047},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24139386415481567},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.218469500541687},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14812549948692322}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:846713276","doi":null,"is_oa":false,"landing_page_url":"http://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/163645/Details","pdf_url":null,"source":{"id":"https://openalex.org/S187826688","display_name":"Journal of Autoimmunity","issn_l":"0896-8411","issn":["0896-8411","1095-9157"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Autoimmunity","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7097407160","https://openalex.org/W4327811536","https://openalex.org/W3140080093","https://openalex.org/W4406847145","https://openalex.org/W7095190056","https://openalex.org/W2273198103","https://openalex.org/W2016166813","https://openalex.org/W2108144643","https://openalex.org/W6996338808","https://openalex.org/W6940189955"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}