{"id":"https://openalex.org/W84335802","doi":"https://doi.org/10.1007/978-1-61779-322-6_11","title":"Restoring Blood Vessels","display_name":"Restoring Blood Vessels","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W84335802","doi":"https://doi.org/10.1007/978-1-61779-322-6_11","mag":"84335802"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-61779-322-6_11","doi":"https://doi.org/10.1007/978-1-61779-322-6_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-61779-322-6_11","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering in Regenerative Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W3143143096","display_name":"Tissue Engineering in Regenerative Medicine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022095208","display_name":"Narutoshi Hibino","orcid":"https://orcid.org/0000-0003-4551-9079","observed_orcids":["https://orcid.org/0000-0003-4551-9079"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Narutoshi Hibino","raw_affiliation_strings":["Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033491632","display_name":"Christopher K. Breuer","orcid":"https://orcid.org/0000-0003-0987-3898","observed_orcids":["https://orcid.org/0000-0003-0987-3898"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Breuer","raw_affiliation_strings":["Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019002625","display_name":"Toshiharu Shinoka","orcid":"https://orcid.org/0000-0002-5173-9249","observed_orcids":["https://orcid.org/0000-0002-5173-9249"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Toshiharu Shinoka","raw_affiliation_strings":["Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019002625"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03415273,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"211","last_page":"220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-engineered-vascular-grafts","display_name":"tissue-engineered vascular grafts","score":0.9750000238418579},{"id":"https://openalex.org/keywords/vascular-tissue-engineering","display_name":"vascular tissue engineering","score":0.8899999856948853},{"id":"https://openalex.org/keywords/biodegradable-scaffolds","display_name":"biodegradable scaffolds","score":0.925000011920929},{"id":"https://openalex.org/keywords/autologous-cells","display_name":"autologous cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.5139999985694885},{"id":"https://openalex.org/keywords/autologous-pericardium","display_name":"autologous pericardium","score":0.7910000085830688},{"id":"https://openalex.org/keywords/allograft","display_name":"allograft","score":0.7400000095367432},{"id":"https://openalex.org/keywords/xenografts","display_name":"xenografts","score":0.9990000128746033},{"id":"https://openalex.org/keywords/artificial-graft","display_name":"artificial graft","score":0.7960000038146973},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.5429999828338623},{"id":"https://openalex.org/keywords/clinical-application","display_name":"clinical application","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.8223973512649536},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.6972571611404419},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5319182276725769},{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.48937100172042847},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.47630631923675537},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.44305863976478577},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.43154746294021606}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-61779-322-6_11","doi":"https://doi.org/10.1007/978-1-61779-322-6_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-61779-322-6_11","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering in Regenerative Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8399999737739563,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W155057832","https://openalex.org/W1499075785","https://openalex.org/W1968445130","https://openalex.org/W1983718931","https://openalex.org/W1991164652","https://openalex.org/W2010748138","https://openalex.org/W2022470130","https://openalex.org/W2044967972","https://openalex.org/W2051272466","https://openalex.org/W2053704719","https://openalex.org/W2070213995","https://openalex.org/W2073889644","https://openalex.org/W2088052594","https://openalex.org/W2113425148","https://openalex.org/W2124184948","https://openalex.org/W2127063151","https://openalex.org/W2130239397","https://openalex.org/W2133108836","https://openalex.org/W2145639716","https://openalex.org/W2150044243","https://openalex.org/W2167137498","https://openalex.org/W2168654826","https://openalex.org/W2400875206","https://openalex.org/W4211147424","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2120608193","https://openalex.org/W4283330959","https://openalex.org/W1555840401","https://openalex.org/W3099528961","https://openalex.org/W2008793756","https://openalex.org/W2055834325","https://openalex.org/W3081247992","https://openalex.org/W2014250108","https://openalex.org/W1967293859","https://openalex.org/W3194248754"],"abstract_inverted_index":{"In":[0,152],"surgical":[1],"repair":[2],"for":[3],"heart":[4],"disease,":[5],"it":[6],"is":[7,82,126,131,197],"sometimes":[8],"necessary":[9],"to":[10,97,162],"fill":[11,136],"or":[12,17,23],"replace":[13],"a":[14,24,83,107],"pathological":[15],"tissue":[16,22,80,121,124],"defect":[18],"with":[19,59,103],"autologous":[20,31,101,179],"graft":[21,40,49],"foreign":[25,141],"grafting":[26],"material.":[27],"To":[28],"date,":[29],"(1)":[30],"pericardium,":[32],"(2)":[33],"allograft,":[34],"(3)":[35],"xenograft,":[36],"and":[37,64,66,74,114,140,173,181,190,199],"(4)":[38],"artificial":[39],"(e.g.,":[41],"Dacron,":[42],"Teflon,":[43],"Gore-Tex)":[44],"have":[45,67],"been":[46],"used":[47],"as":[48,106,134,205],"materials.":[50],"These":[51,184],"grafts,":[52],"however,":[53],"lack":[54],"growth":[55],"potential,":[56],"are":[57],"associated":[58],"increased":[60],"risk":[61],"of":[62,76,92,112,120,159,166],"thrombosis":[63],"infection,":[65],"limited":[68],"durability,":[69],"thus":[70],"increasing":[71],"the":[72,89,93,110,128,137,164,193,200,206],"morbidity":[73],"mortality":[75],"their":[77],"application.":[78],"Vascular":[79],"engineering":[81,113,125],"relatively":[84],"new":[85],"concept":[86],"proposed":[87],"in":[88,170,174],"latter":[90],"half":[91],"1980s.":[94],"It":[95],"aims":[96],"produce":[98],"neotissue":[99],"from":[100],"cells":[102,135,180],"biodegradable":[104,182],"polymer":[105,130],"scaffold":[108,129],"by":[109,123,188,192],"application":[111],"biological":[115],"principles.":[116],"The":[117],"greatest":[118],"advantage":[119],"constructed":[122],"that":[127],"completely":[132],"biodegraded":[133],"extracellular":[138],"stroma,":[139],"materials":[142],"do":[143],"not":[144,191],"remain":[145],"at":[146],"later":[147],"time":[148],"points":[149],"after":[150],"transplant.":[151],"this":[153],"review,":[154],"we":[155],"provide":[156],"an":[157],"overview":[158],"our":[160],"work":[161],"demonstrate":[163],"advantages":[165],"tissue-engineered":[167],"vascular":[168],"grafts":[169],"animal":[171],"models":[172],"human":[175],"clinical":[176],"applications":[177],"using":[178],"scaffolds.":[183],"keywords":[185,201],"were":[186],"added":[187],"machine":[189],"authors.":[194],"This":[195],"process":[196],"experimental":[198],"may":[202],"be":[203],"updated":[204],"learning":[207],"algorithm":[208],"improves.":[209]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
