{"id":"https://openalex.org/W841744542","doi":null,"title":"A survey of dynamical genetics.","display_name":"A survey of dynamical genetics.","publication_year":2004,"publication_date":"2004-05-01","ids":{"openalex":"https://openalex.org/W841744542","mag":"841744542","pmid":"https://pubmed.ncbi.nlm.nih.gov/15612189"},"language":"en","primary_location":{"id":"pmid:15612189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15612189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rivista di biologia","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017280702","display_name":"Parisi Valerio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valerio Parisi","raw_affiliation_strings":["Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 di Roma \"La Sapienza\", Roma. Valerio.Parisi@uniroma1.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 di Roma \"La Sapienza\", Roma. Valerio.Parisi@uniroma1.it","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052752195","display_name":"Valeria De Fonzo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Valeria De Fonzo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012007149","display_name":"Filippo Aluffi-Pentini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Filippo Aluffi-Pentini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"97","issue":"2","first_page":"223","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.7896000146865845,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.7896000146865845,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.1370999962091446,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transposable-elements","display_name":"transposable elements","score":0.8230000138282776},{"id":"https://openalex.org/keywords/trinucleotide-repeat-expansion","display_name":"trinucleotide repeat expansion","score":0.9139999747276306},{"id":"https://openalex.org/keywords/dna-repair-enzymes","display_name":"DNA repair enzymes","score":0.47099998593330383},{"id":"https://openalex.org/keywords/horizontal-transmission","display_name":"horizontal transmission","score":0.7429999709129333},{"id":"https://openalex.org/keywords/creutzfeldt-jakob-disease","display_name":"Creutzfeldt-Jakob disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/g-quadruplex","display_name":"G-quadruplex","score":0.871999979019165},{"id":"https://openalex.org/keywords/central-dogma","display_name":"central dogma","score":0.7260000109672546},{"id":"https://openalex.org/keywords/epigenetic-inheritance","display_name":"epigenetic inheritance","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6026591062545776},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5835892558097839},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5815936326980591},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.5609987378120422},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5440719127655029},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43688175082206726},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.35834890604019165},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3314066529273987},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.24355265498161316},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007562","descriptor_name":"Creutzfeldt-Jakob Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008967","descriptor_name":"Molecular Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:15612189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15612189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rivista di biologia","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/237542","doi":null,"is_oa":false,"landing_page_url":"http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000225049300004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=0c7ff228ccbaaa74236f48834a34396a","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:841744542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15612189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":147,"referenced_works":["https://openalex.org/W49184055","https://openalex.org/W169978917","https://openalex.org/W193121366","https://openalex.org/W1491376216","https://openalex.org/W1513744325","https://openalex.org/W1531180332","https://openalex.org/W1532858692","https://openalex.org/W1546576947","https://openalex.org/W1574461315","https://openalex.org/W1663646904","https://openalex.org/W1762594989","https://openalex.org/W1799638222","https://openalex.org/W1824348478","https://openalex.org/W1967778765","https://openalex.org/W1968403527","https://openalex.org/W1970086776","https://openalex.org/W1970574292","https://openalex.org/W1972376393","https://openalex.org/W1972813488","https://openalex.org/W1974224833","https://openalex.org/W1975478972","https://openalex.org/W1976111913","https://openalex.org/W1977660940","https://openalex.org/W1977935122","https://openalex.org/W1982073044","https://openalex.org/W1983359810","https://openalex.org/W1983644993","https://openalex.org/W1984257291","https://openalex.org/W1985242213","https://openalex.org/W1986071629","https://openalex.org/W1986196133","https://openalex.org/W1986937402","https://openalex.org/W1987617311","https://openalex.org/W1988551012","https://openalex.org/W1990635146","https://openalex.org/W1991320212","https://openalex.org/W1992579096","https://openalex.org/W1994745117","https://openalex.org/W1995117714","https://openalex.org/W1995136541","https://openalex.org/W1997973599","https://openalex.org/W1998859901","https://openalex.org/W2003411878","https://openalex.org/W2004265442","https://openalex.org/W2007513570","https://openalex.org/W2008370788","https://openalex.org/W2009616913","https://openalex.org/W2010042331","https://openalex.org/W2010251411","https://openalex.org/W2010595848","https://openalex.org/W2011428226","https://openalex.org/W2011840262","https://openalex.org/W2013413025","https://openalex.org/W2015625843","https://openalex.org/W2015941944","https://openalex.org/W2017792279","https://openalex.org/W2018272689","https://openalex.org/W2020700266","https://openalex.org/W2026806597","https://openalex.org/W2029122003","https://openalex.org/W2030345501","https://openalex.org/W2031559689","https://openalex.org/W2031598812","https://openalex.org/W2033796334","https://openalex.org/W2034798093","https://openalex.org/W2034955342","https://openalex.org/W2036386990","https://openalex.org/W2036534913","https://openalex.org/W2036872469","https://openalex.org/W2037859334","https://openalex.org/W2038560210","https://openalex.org/W2039511163","https://openalex.org/W2040253688","https://openalex.org/W2042399343","https://openalex.org/W2044288118","https://openalex.org/W2044480512","https://openalex.org/W2044767860","https://openalex.org/W2045751930","https://openalex.org/W2049151807","https://openalex.org/W2057787531","https://openalex.org/W2058831382","https://openalex.org/W2060017837","https://openalex.org/W2060356703","https://openalex.org/W2061481377","https://openalex.org/W2064256060","https://openalex.org/W2065646289","https://openalex.org/W2065814033","https://openalex.org/W2066029556","https://openalex.org/W2066468421","https://openalex.org/W2072894498","https://openalex.org/W2073722866","https://openalex.org/W2073742539","https://openalex.org/W2077347620","https://openalex.org/W2078119618","https://openalex.org/W2079385075","https://openalex.org/W2082856283","https://openalex.org/W2084267545","https://openalex.org/W2084902262","https://openalex.org/W2086438483","https://openalex.org/W2089997318","https://openalex.org/W2090058042","https://openalex.org/W2092781336","https://openalex.org/W2093394063","https://openalex.org/W2095321122","https://openalex.org/W2103445042","https://openalex.org/W2104775326","https://openalex.org/W2105004449","https://openalex.org/W2106111891","https://openalex.org/W2106549255","https://openalex.org/W2109234462","https://openalex.org/W2110105435","https://openalex.org/W2110436881","https://openalex.org/W2110811750","https://openalex.org/W2115182128","https://openalex.org/W2116729229","https://openalex.org/W2117016125","https://openalex.org/W2121359743","https://openalex.org/W2123316289","https://openalex.org/W2123408329","https://openalex.org/W2123546399","https://openalex.org/W2124258497","https://openalex.org/W2128237281","https://openalex.org/W2131095547","https://openalex.org/W2132070326","https://openalex.org/W2133330366","https://openalex.org/W2134770471","https://openalex.org/W2141542118","https://openalex.org/W2142071465","https://openalex.org/W2145949628","https://openalex.org/W2145972251","https://openalex.org/W2146354013","https://openalex.org/W2147208616","https://openalex.org/W2147303286","https://openalex.org/W2150659226","https://openalex.org/W2152294076","https://openalex.org/W2164599456","https://openalex.org/W2165802059","https://openalex.org/W2166160777","https://openalex.org/W2166976426","https://openalex.org/W2167435540","https://openalex.org/W2167884034","https://openalex.org/W2169760747","https://openalex.org/W2170722275","https://openalex.org/W2172207438","https://openalex.org/W2522522279","https://openalex.org/W2999074976","https://openalex.org/W3187872748"],"related_works":["https://openalex.org/W7049104854","https://openalex.org/W2104775326","https://openalex.org/W1970086776","https://openalex.org/W2052654393","https://openalex.org/W3030111445","https://openalex.org/W2039214189","https://openalex.org/W4252810853","https://openalex.org/W4247177974","https://openalex.org/W4407829221","https://openalex.org/W2090101697"],"abstract_inverted_index":{"The":[0,136],"classical":[1],"view":[2],"of":[3,11,48,55,57,97,100,103,112,138,144,160,168],"genetics":[4],"is":[5,61,107,117,122],"based":[6],"on":[7],"the":[8,25,45,53,58,75,83,89,95,98,120],"central":[9],"dogma":[10],"molecular":[12],"biology":[13],"that":[14,119,172],"assigns":[15],"to":[16,24,67,182],"DNA":[17,27,64,121,212],"a":[18,109,125,158,179,187],"fundamental":[19],"but":[20,199],"static":[21,180],"role.":[22],"According":[23],"dogma,":[26],"can":[28,43,147],"be":[29,148],"duplicated":[30],"only":[31,62,192],"in":[32,50,124],"identical":[33],"copies":[34],"(except":[35],"for":[36,185],"random":[37],"errors),":[38],"and":[39,69,82,143,164,184,206,209],"no":[40,174],"smart":[41,133],"mechanism":[42],"alter":[44],"information":[46,60],"content":[47],"DNA:":[49],"more":[51,93,126],"detail,":[52],"direction":[54],"transfer":[56],"genetic":[59],"from":[63,74],"through":[65],"RNA":[66],"proteins":[68],"never":[70],"backwards.":[71],"However,":[72],"starting":[73],"so-called":[76,84],"dynamic":[77,85,141,162],"genome":[78],"(McClintock's":[79],"jumping":[80],"genes),":[81],"mutations":[86],"(such":[87],"as":[88,203,215],"trinucleotide":[90],"expansion":[91],"or,":[92],"generally,":[94],"instability":[96],"number":[99,159],"tandem":[101],"repeats":[102],"longer":[104],"sequences),":[105],"there":[106],"now":[108],"growing":[110],"body":[111],"important":[113],"cases":[114],"where":[115],"it":[116],"known":[118,214],"altered":[123],"or":[127],"less":[128],"sophisticated":[129],"way,":[130],"often":[131],"by":[132],"enzymatic":[134],"mechanisms.":[135],"study":[137],"all":[139],"such":[140,161,202],"phenomena":[142,167,201],"their":[145],"interpretations":[146],"naturally":[149],"called":[150],"dynamical":[151,188],"genetics.":[152],"In":[153],"this":[154],"survey":[155],"we":[156],"examine":[157],"phenomena,":[163],"also":[165],"some":[166,197],"great":[169],"biological":[170],"importance":[171],"have":[173],"universally":[175],"accepted":[176],"explanation":[177],"within":[178],"approach":[181],"genetics,":[183],"which":[186],"interpretation":[189],"has":[190],"been":[191],"proposed.":[193],"Important":[194],"examples":[195],"are":[196],"controversial":[198],"interesting":[200],"horizontal":[204],"transmission":[205],"Creutzfeldt-Jakob":[207],"Disease,":[208],"those":[210],"peculiar":[211],"structures":[213],"G-quadruplexes.":[216]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
