{"id":"https://openalex.org/W83661986","doi":null,"title":"Correlations between periodontal tissue breakdown and cell populations.","display_name":"Correlations between periodontal tissue breakdown and cell populations.","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W83661986","mag":"83661986","pmid":"https://pubmed.ncbi.nlm.nih.gov/1947971"},"language":"en","primary_location":{"id":"pmid:1947971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1947971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072656877","display_name":"Urs E. Zappa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U E Zappa","raw_affiliation_strings":["Department of Periodontology, Eastman Dental Center, Rochester, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology, Eastman Dental Center, Rochester, New York","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109198295","display_name":"Alan M. Polson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M Polson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5081433393","display_name":"M A Espeland","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M A Espeland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0133015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"101","issue":"10","first_page":"1279","last_page":"85"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13768","display_name":"Oral and gingival health research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/experimental-periodontitis","display_name":"experimental periodontitis","score":0.9039999842643738},{"id":"https://openalex.org/keywords/periodontal-destruction","display_name":"periodontal tissue destruction","score":0.8989999890327454},{"id":"https://openalex.org/keywords/polymorphonuclear-leukocytes","display_name":"polymorphonuclear leukocytes","score":0.9350000023841858},{"id":"https://openalex.org/keywords/plasma-cells","display_name":"plasma cells","score":0.8460000157356262},{"id":"https://openalex.org/keywords/alveolar-bone-loss","display_name":"alveolar bone loss","score":0.9229999780654907},{"id":"https://openalex.org/keywords/ligature-induced-periodontitis","display_name":"ligature-induced periodontitis","score":0.8019999861717224},{"id":"https://openalex.org/keywords/squirrel-monkey","display_name":"squirrel monkey","score":0.7260000109672546},{"id":"https://openalex.org/keywords/gingivitis","display_name":"gingivitis","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.8053703904151917},{"id":"https://openalex.org/C151279780","wikidata":"https://www.wikidata.org/wiki/Q143588","display_name":"Dental alveolus","level":2,"score":0.7796298265457153},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.6603050231933594},{"id":"https://openalex.org/C61260549","wikidata":"https://www.wikidata.org/wiki/Q5133813","display_name":"Clinical attachment loss","level":3,"score":0.6558747291564941},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5952310562133789},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5431550741195679},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.43621134757995605},{"id":"https://openalex.org/C41868710","wikidata":"https://www.wikidata.org/wiki/Q540092","display_name":"Periodontal fiber","level":2,"score":0.424820214509964},{"id":"https://openalex.org/C2779306806","wikidata":"https://www.wikidata.org/wiki/Q448692","display_name":"Alveolar process","level":2,"score":0.4219818711280823},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3538334369659424}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003238","descriptor_name":"Connective Tissue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003238","descriptor_name":"Connective Tissue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003238","descriptor_name":"Connective Tissue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010519","descriptor_name":"Periodontium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010519","descriptor_name":"Periodontium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010519","descriptor_name":"Periodontium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012453","descriptor_name":"Saimiri","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012453","descriptor_name":"Saimiri","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012453","descriptor_name":"Saimiri","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1947971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1947971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia","raw_type":"Journal Article"},{"id":"mag:83661986","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1947971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2411916331","https://openalex.org/W45536960","https://openalex.org/W2553401689","https://openalex.org/W3097549124","https://openalex.org/W1835539422","https://openalex.org/W2350323585","https://openalex.org/W3106804501","https://openalex.org/W2032240114","https://openalex.org/W83661986","https://openalex.org/W2109820117"],"abstract_inverted_index":{"The":[0],"present":[1],"study":[2],"evaluated":[3,42],"correlations":[4,157],"between":[5],"periodontal":[6,168],"breakdown":[7],"and":[8,30,33,45,48,61,80,93,102,108,118,126,134,148],"cell":[9],"populations":[10,66],"during":[11,164],"an":[12],"experimental":[13],"periodontitis.":[14],"Periodontitis":[15],"was":[16,41,146],"induced":[17],"by":[18,54,73],"tying":[19],"plaque":[20],"retentive":[21],"silk":[22],"ligatures":[23],"at":[24,43,69],"the":[25,81,129,152,159],"gingival":[26],"margins":[27],"of":[28,35,57,84,89,106,110,132,154,162,167],"maxillary":[29],"mandibular":[31],"bicuspids":[32],"molars":[34],"4":[36],"squirrel":[37],"monkeys.":[38],"Periodontal":[39,143],"destruction":[40,145],"baseline,":[44,87],"3,":[46,100,124],"7":[47,101,125],"14":[49,103,127],"days":[50],"after":[51],"ligature":[52],"placement":[53],"measuring":[55],"loss":[56,105,109],"connective":[58,90],"tissue":[59,91,144,169],"attachment":[60,92,107],"crestal":[62,94],"alveolar":[63,95],"bone.":[64],"Cell":[65],"were":[67,97,112,121,136],"characterized":[68],"corresponding":[70],"time":[71],"points":[72],"counting":[74],"polymorphonuclear":[75],"leucocytes":[76],"(PMNs),":[77],"plasma":[78,119],"cells":[79,120,133],"total":[82,130],"number":[83,131,153],"cells.":[85],"At":[86,99,115,123],"levels":[88],"bone":[96,111],"normal.":[98],"days,":[104,128],"statistically":[113,137],"significant.":[114],"baseline":[116],"PMNs":[117,135,163],"sparse.":[122],"significantly":[138],"increased":[139],"compared":[140],"to":[141],"baseline.":[142],"positively":[147],"strongly":[149],"correlated":[150],"with":[151],"PMNs.":[155],"These":[156],"emphasize":[158],"potential":[160],"role":[161],"acute":[165],"bursts":[166],"destruction.":[170]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}