{"id":"https://openalex.org/W8353733","doi":"https://doi.org/10.1007/978-0-387-72430-0_21","title":"Gene Therapy Approaches for Lung Cancer","display_name":"Gene Therapy Approaches for Lung Cancer","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W8353733","doi":"https://doi.org/10.1007/978-0-387-72430-0_21","mag":"8353733"},"language":"en","primary_location":{"id":"doi:10.1007/978-0-387-72430-0_21","doi":"https://doi.org/10.1007/978-0-387-72430-0_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-0-387-72430-0_21","pdf_url":null,"source":{"id":"https://openalex.org/S4210191083","display_name":"Molecular pathology library","issn_l":"1935-987X","issn":["1935-987X","1935-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pathology Library","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W626799224","display_name":"Molecular Pathology of Lung Diseases"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027152610","display_name":"Jack A. Roth","orcid":"https://orcid.org/0000-0002-8955-1313","observed_orcids":["https://orcid.org/0000-0002-8955-1313"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jack A. Roth","raw_affiliation_strings":["Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027152610"],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00190259,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"219","last_page":"225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.2054000049829483,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.021800000220537186,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.878000020980835},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":1.0},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.9879999756813049},{"id":"https://openalex.org/keywords/gene-transfer","display_name":"gene transfer","score":0.6589999794960022},{"id":"https://openalex.org/keywords/tobacco-smoke-carcinogens","display_name":"tobacco smoke carcinogens","score":0.7229999899864197},{"id":"https://openalex.org/keywords/dna-repair-genes","display_name":"DNA repair genes","score":0.7549999952316284},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7325290441513062},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6630289554595947},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.6461185812950134},{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.629332423210144},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5832652449607849},{"id":"https://openalex.org/C2778355491","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Tobacco smoke","level":2,"score":0.5683453679084778},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.5091208815574646},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.4905323386192322},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.458659827709198},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4534086287021637},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37232333421707153},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.355658620595932},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.2889649569988251},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26172488927841187},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-0-387-72430-0_21","doi":"https://doi.org/10.1007/978-0-387-72430-0_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-0-387-72430-0_21","pdf_url":null,"source":{"id":"https://openalex.org/S4210191083","display_name":"Molecular pathology library","issn_l":"1935-987X","issn":["1935-987X","1935-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pathology Library","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1579336954","https://openalex.org/W1790220839","https://openalex.org/W1950719160","https://openalex.org/W1964617786","https://openalex.org/W1967986995","https://openalex.org/W1968450421","https://openalex.org/W1969785946","https://openalex.org/W1973478663","https://openalex.org/W1973568055","https://openalex.org/W1973886069","https://openalex.org/W1976056213","https://openalex.org/W1976936729","https://openalex.org/W1977686001","https://openalex.org/W1990406980","https://openalex.org/W1990614709","https://openalex.org/W2001571816","https://openalex.org/W2008420379","https://openalex.org/W2010781234","https://openalex.org/W2012322426","https://openalex.org/W2021875656","https://openalex.org/W2022790376","https://openalex.org/W2023917814","https://openalex.org/W2029533557","https://openalex.org/W2033791403","https://openalex.org/W2038096267","https://openalex.org/W2044217649","https://openalex.org/W2045086385","https://openalex.org/W2070051352","https://openalex.org/W2074114480","https://openalex.org/W2075447939","https://openalex.org/W2086532812","https://openalex.org/W2092268147","https://openalex.org/W2094418791","https://openalex.org/W2098287668","https://openalex.org/W2105327099","https://openalex.org/W2124052729","https://openalex.org/W2142058281","https://openalex.org/W2150732996","https://openalex.org/W2154589271","https://openalex.org/W2158446937","https://openalex.org/W2160176818","https://openalex.org/W2167597785","https://openalex.org/W2325667407","https://openalex.org/W2407896503","https://openalex.org/W2416102534","https://openalex.org/W2416306209","https://openalex.org/W2419086488","https://openalex.org/W2437300897"],"related_works":["https://openalex.org/W3024276562","https://openalex.org/W2443387106","https://openalex.org/W2378022566","https://openalex.org/W3031409553","https://openalex.org/W2505483119","https://openalex.org/W2020761124","https://openalex.org/W1482809148","https://openalex.org/W2070526286","https://openalex.org/W1655744316","https://openalex.org/W2246446342"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
