{"id":"https://openalex.org/W834045156","doi":null,"title":"Clinical and biological insights into the novel epigenetic regulator TET2","display_name":"Clinical and biological insights into the novel epigenetic regulator TET2","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W834045156","mag":"834045156"},"language":"en","primary_location":{"id":"pmh:oai:repository.ubn.ru.nl:2066/139507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/139507","pdf_url":"http://hdl.handle.net/2066/139507","source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2066/139507","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062377767","display_name":"Mariam G. Aslanyan","orcid":"https://orcid.org/0000-0001-5675-2031","observed_orcids":["https://orcid.org/0000-0001-5675-2031"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mariam G. Aslanyan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5675-2031","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5062377767"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7285000085830688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.7285000085830688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.094200000166893,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tet2","display_name":"TET2","score":1.0},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.8370000123977661},{"id":"https://openalex.org/keywords/dna-demethylation","display_name":"DNA demethylation","score":0.9259999990463257},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.3919999897480011},{"id":"https://openalex.org/keywords/biological-function","display_name":"biological function","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.8210994601249695},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.7644854187965393},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4661515951156616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4307851791381836},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.41247445344924927},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3550519645214081},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2970595955848694},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09890040755271912},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0833774209022522}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repository.ubn.ru.nl:2066/139507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/139507","pdf_url":"http://hdl.handle.net/2066/139507","source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/139507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/139507","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:834045156","doi":null,"is_oa":false,"landing_page_url":"https://repository.ubn.ru.nl/bitstream/2066/139507/1/139507.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.ubn.ru.nl:2066/139507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/139507","pdf_url":"http://hdl.handle.net/2066/139507","source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322977","display_name":"EORTC Charitable Trust","ror":"https://ror.org/034wxcc35"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W834045156.pdf","grobid_xml":"https://content.openalex.org/works/W834045156.grobid-xml"},"referenced_works_count":120,"referenced_works":["https://openalex.org/W45064441","https://openalex.org/W191043282","https://openalex.org/W1571539585","https://openalex.org/W1907671556","https://openalex.org/W1963736125","https://openalex.org/W1966468838","https://openalex.org/W1966554737","https://openalex.org/W1967224500","https://openalex.org/W1967269362","https://openalex.org/W1971157495","https://openalex.org/W1974749085","https://openalex.org/W1975702835","https://openalex.org/W1976573435","https://openalex.org/W1976812199","https://openalex.org/W1978788671","https://openalex.org/W1978972655","https://openalex.org/W1981258144","https://openalex.org/W1981354816","https://openalex.org/W1981543052","https://openalex.org/W1981564870","https://openalex.org/W1982315838","https://openalex.org/W1982640053","https://openalex.org/W1987930421","https://openalex.org/W1991698857","https://openalex.org/W1993236149","https://openalex.org/W1993627126","https://openalex.org/W1993672713","https://openalex.org/W1995675594","https://openalex.org/W1997127542","https://openalex.org/W1997556856","https://openalex.org/W1997998180","https://openalex.org/W1998367819","https://openalex.org/W2005458309","https://openalex.org/W2009127763","https://openalex.org/W2010391644","https://openalex.org/W2012753533","https://openalex.org/W2014623973","https://openalex.org/W2015085004","https://openalex.org/W2016923091","https://openalex.org/W2017840637","https://openalex.org/W2021785548","https://openalex.org/W2024373518","https://openalex.org/W2025408251","https://openalex.org/W2028078153","https://openalex.org/W2032814455","https://openalex.org/W2032882684","https://openalex.org/W2033514598","https://openalex.org/W2035409103","https://openalex.org/W2038449573","https://openalex.org/W2040159352","https://openalex.org/W2041191257","https://openalex.org/W2041690843","https://openalex.org/W2042871287","https://openalex.org/W2043216151","https://openalex.org/W2043387647","https://openalex.org/W2046878942","https://openalex.org/W2051974375","https://openalex.org/W2054643318","https://openalex.org/W2055270130","https://openalex.org/W2057129764","https://openalex.org/W2059397419","https://openalex.org/W2063544405","https://openalex.org/W2063789328","https://openalex.org/W2069024509","https://openalex.org/W2071365780","https://openalex.org/W2072713007","https://openalex.org/W2073587729","https://openalex.org/W2073979766","https://openalex.org/W2075265769","https://openalex.org/W2075899469","https://openalex.org/W2077359452","https://openalex.org/W2078972833","https://openalex.org/W2081895311","https://openalex.org/W2084295010","https://openalex.org/W2084334750","https://openalex.org/W2086557601","https://openalex.org/W2088708165","https://openalex.org/W2095184701","https://openalex.org/W2096153482","https://openalex.org/W2097743943","https://openalex.org/W2099212333","https://openalex.org/W2099343472","https://openalex.org/W2100663913","https://openalex.org/W2102083376","https://openalex.org/W2105665764","https://openalex.org/W2107398329","https://openalex.org/W2108664872","https://openalex.org/W2110484521","https://openalex.org/W2111754589","https://openalex.org/W2111957254","https://openalex.org/W2113950481","https://openalex.org/W2114435237","https://openalex.org/W2117247812","https://openalex.org/W2120440386","https://openalex.org/W2121090755","https://openalex.org/W2126817554","https://openalex.org/W2129270269","https://openalex.org/W2131072337","https://openalex.org/W2131860315","https://openalex.org/W2132912591","https://openalex.org/W2134061682","https://openalex.org/W2134349183","https://openalex.org/W2140929811","https://openalex.org/W2141554152","https://openalex.org/W2144395887","https://openalex.org/W2144892629","https://openalex.org/W2147370638","https://openalex.org/W2149573012","https://openalex.org/W2150470057","https://openalex.org/W2151222524","https://openalex.org/W2152451432","https://openalex.org/W2154313451","https://openalex.org/W2155104532","https://openalex.org/W2156386262","https://openalex.org/W2169172058","https://openalex.org/W2170515966","https://openalex.org/W2171690009","https://openalex.org/W2249312162","https://openalex.org/W2314529838","https://openalex.org/W2403241400"],"related_works":["https://openalex.org/W7094293873","https://openalex.org/W2910826702","https://openalex.org/W3025782369","https://openalex.org/W2470651031","https://openalex.org/W1490301870","https://openalex.org/W2119859172","https://openalex.org/W3177656430","https://openalex.org/W2899054271","https://openalex.org/W6986229681","https://openalex.org/W7064005153"],"abstract_inverted_index":{"\\n":[0],"Contains":[1],"fulltext":[2],":\\n":[3],"139507.pdf":[4],"(Publisher\u2019s":[5],"version":[6],")":[7],"(Open":[8],"Access)\\n":[9]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}