{"id":"https://openalex.org/W833885448","doi":null,"title":"Temporal Processing and Neurodevelopmental Disorders: Insights from Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and 22q11.2 Deletion Syndrome","display_name":"Temporal Processing and Neurodevelopmental Disorders: Insights from Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and 22q11.2 Deletion Syndrome","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W833885448","mag":"833885448"},"language":"en","primary_location":{"id":"pmh:oai:escholarship.org/ark:/13030/qt2sp4g726","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/2sp4g726","pdf_url":"https://escholarship.org/uc/item/2sp4g726","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"etd"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/uc/item/2sp4g726","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090967483","display_name":"Laurie A. Brenner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Laurie A. Brenner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5090967483"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.6259999871253967,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.6259999871253967,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10788","display_name":"Neuroscience and Music Perception","score":0.18039999902248383,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.1151999980211258,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/temporal-processing","display_name":"temporal processing","score":0.9940000176429749},{"id":"https://openalex.org/keywords/interval-timing","display_name":"interval timing","score":0.9570000171661377},{"id":"https://openalex.org/keywords/time-reproduction","display_name":"time reproduction","score":0.5960000157356262},{"id":"https://openalex.org/keywords/temporal-variation","display_name":"temporal variation","score":0.5989999771118164},{"id":"https://openalex.org/keywords/neurodevelopmental-disorders","display_name":"neurodevelopmental disorders","score":0.7960000038146973},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9980000257492065},{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":1.0},{"id":"https://openalex.org/keywords/22q11-2-deletion-syndrome","display_name":"22q11.2 deletion syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/frontostriatal-circuits","display_name":"frontostriatal circuits","score":0.8759999871253967},{"id":"https://openalex.org/keywords/inattention","display_name":"inattention","score":0.7549999952316284},{"id":"https://openalex.org/keywords/hyperactivity","display_name":"hyperactivity","score":0.8090000152587891},{"id":"https://openalex.org/keywords/autistic-traits","display_name":"autistic traits","score":0.9639999866485596},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.9589999914169312},{"id":"https://openalex.org/keywords/endophenotypes","display_name":"endophenotypes","score":0.8040000200271606},{"id":"https://openalex.org/keywords/age-related-development","display_name":"age-related development","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.7143216133117676},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.6802641153335571},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6610599160194397},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.6235823631286621},{"id":"https://openalex.org/C187869287","wikidata":"https://www.wikidata.org/wiki/Q2032061","display_name":"Endophenotype","level":3,"score":0.5845113396644592},{"id":"https://openalex.org/C172081034","wikidata":"https://www.wikidata.org/wiki/Q185961","display_name":"Time perception","level":3,"score":0.569750964641571},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.46045592427253723},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.4473492503166199},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3021284341812134},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.263461709022522},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.24304452538490295},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1558920443058014}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:escholarship.org/ark:/13030/qt2sp4g726","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/2sp4g726","pdf_url":"https://escholarship.org/uc/item/2sp4g726","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"etd"},{"id":"pmh:qt2sp4g726","doi":null,"is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/2sp4g726","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brenner, Laurie Ashley. (2012). Temporal Processing and Neurodevelopmental Disorders: Insights from Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and 22q11.2 Deletion Syndrome. UCLA: Psychology 0780. Retrieved from: http://www.escholarship.org/uc/item/2sp4g726","raw_type":"dissertation"},{"id":"mag:833885448","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/content/qt2sp4g726/qt2sp4g726.pdf?t=npezwr","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:escholarship.org/ark:/13030/qt2sp4g726","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/2sp4g726","pdf_url":"https://escholarship.org/uc/item/2sp4g726","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"etd"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G5596416781","display_name":"Neurodevelopment and Psychosis in the 22q11.2 Deletion Syndrome","funder_award_id":"R01MH085953","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7001273160","display_name":"Heterogeneity in Autism Spectrum Disorders: Biological Mechanisms, Trajectories, and Treatment Response","funder_award_id":"P50HD055784","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7978069354","display_name":"Prospective predictors of alcohol expectancies in children with and without ADHD","funder_award_id":"R03AA020186","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G8425615888","display_name":null,"funder_award_id":"MH085953","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G858670424","display_name":"Neural and Phenotypic Correlates of Autism Risk Genes","funder_award_id":"R01HD065280","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W833885448.pdf","grobid_xml":"https://content.openalex.org/works/W833885448.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W1524959298","https://openalex.org/W1579913460","https://openalex.org/W1588132147","https://openalex.org/W1659384861","https://openalex.org/W1875653175","https://openalex.org/W1881877064","https://openalex.org/W1968055735","https://openalex.org/W1977065133","https://openalex.org/W1982756613","https://openalex.org/W1983680854","https://openalex.org/W1983866206","https://openalex.org/W1988742833","https://openalex.org/W1992492993","https://openalex.org/W1992943232","https://openalex.org/W1993047476","https://openalex.org/W1993232887","https://openalex.org/W2001847460","https://openalex.org/W2002012536","https://openalex.org/W2003392453","https://openalex.org/W2007382757","https://openalex.org/W2008785629","https://openalex.org/W2013363183","https://openalex.org/W2013818763","https://openalex.org/W2015463602","https://openalex.org/W2016513420","https://openalex.org/W2016967233","https://openalex.org/W2017147845","https://openalex.org/W2017588448","https://openalex.org/W2018736722","https://openalex.org/W2021519456","https://openalex.org/W2023794469","https://openalex.org/W2026866732","https://openalex.org/W2031627574","https://openalex.org/W2033447318","https://openalex.org/W2034744443","https://openalex.org/W2038136588","https://openalex.org/W2049643291","https://openalex.org/W2054856852","https://openalex.org/W2055853495","https://openalex.org/W2060113175","https://openalex.org/W2066331009","https://openalex.org/W2067147530","https://openalex.org/W2067774627","https://openalex.org/W2068549840","https://openalex.org/W2069195020","https://openalex.org/W2074369357","https://openalex.org/W2075519476","https://openalex.org/W2083972263","https://openalex.org/W2086611502","https://openalex.org/W2087941344","https://openalex.org/W2092159891","https://openalex.org/W2092869199","https://openalex.org/W2094707772","https://openalex.org/W2095116449","https://openalex.org/W2095251402","https://openalex.org/W2096672810","https://openalex.org/W2098498763","https://openalex.org/W2101247622","https://openalex.org/W2103570990","https://openalex.org/W2105897900","https://openalex.org/W2109370255","https://openalex.org/W2111030679","https://openalex.org/W2122790331","https://openalex.org/W2129566263","https://openalex.org/W2130781239","https://openalex.org/W2136332751","https://openalex.org/W2138298738","https://openalex.org/W2139626338","https://openalex.org/W2144446993","https://openalex.org/W2151297547","https://openalex.org/W2155144545","https://openalex.org/W2157694712","https://openalex.org/W2159146218","https://openalex.org/W2160324605","https://openalex.org/W2171565894"],"related_works":["https://openalex.org/W1587109551","https://openalex.org/W274764465","https://openalex.org/W7099803171","https://openalex.org/W2044493102","https://openalex.org/W1983866206","https://openalex.org/W3025656572","https://openalex.org/W122568077","https://openalex.org/W2793815015","https://openalex.org/W2789866634","https://openalex.org/W1983680854"],"abstract_inverted_index":{"The":[0,35,128,195,305],"representation":[1],"and":[2,75,99,140,155,157,168,193,215,228,276,320,329],"utilization":[3],"of":[4,16,24,31,49,66,72,124,130,163,204,210,235,255,261,281,298,312,318,324,334,340,349],"temporal":[5,39,73,111,313],"information":[6],"is":[7,113],"a":[8,32,64,105,114,121,179,200],"basic":[9],"human":[10],"ability":[11,36],"that":[12,117],"permeates":[13],"many":[14],"aspects":[15],"daily":[17],"life,":[18],"such":[19],"as":[20,120,183],"estimating":[21],"the":[22,29,45,69,76,100,160,236,251,264,274,293,296,322,338,347],"duration":[23,30],"an":[25,184],"event":[26],"or":[27],"predicting":[28],"behavioral":[33],"response.":[34],"to":[37,56,171,186,286,346],"discriminate":[38],"durations":[40,209],"develops":[41],"in":[42,68,82,91,142,151,190,222,233,263,292,337],"infancy;":[43],"however,":[44,291],"precision":[46],"(i.e.,":[47],"consistency)":[48],"timing":[50,84,206],"abilities":[51],"improves":[52],"from":[53,104],"early":[54],"childhood":[55],"adolescence.":[57],"In":[58],"recent":[59],"years,":[60],"there":[61],"has":[62],"been":[63,80],"surge":[65],"interest":[67],"neurobiological":[70,344],"basis":[71],"processing,":[74],"frontal-striatal":[77,126,335],"systems":[78],"have":[79,307],"implicated":[81],"second-range":[83],"functions.":[85],"Frontal-striatal":[86],"abnormalities":[87],"are":[88],"well":[89],"documented":[90],"attention-deficit/hyperactivity":[92],"disorder":[93],"(ADHD),":[94],"autism":[95],"spectrum":[96],"disorders":[97],"(ASD),":[98],"genetic":[101],"syndrome":[102],"resulting":[103],"deletion":[106],"at":[107],"22q11.2":[108],"(22q11DS);":[109],"therefore,":[110],"processing":[112,314],"candidate":[115],"endophenotype":[116],"may":[118],"serve":[119],"clinical":[122],"indicator":[123],"aberrant":[125],"function.":[127],"purpose":[129],"this":[131],"study":[132],"was":[133,199,250,300],"to:":[134],"(1)":[135],"characterize":[136],"time":[137,152,172,196,256],"reproduction":[138,153,173,197,226,257],"accuracy":[139,154,227],"variability":[141,284,328],"three":[143,180,237],"different":[144],"neurodevelopmental":[145],"disorders,":[146],"(2)":[147],"model":[148],"age-related":[149],"changes":[150],"consistency,":[156],"(3)":[158],"assess":[159],"relative":[161,285],"contributions":[162],"symptom":[164,350],"dimensions":[165,317],"(inattention,":[166],"hyperactivity,":[167],"autistic":[169],"traits)":[170],"performance.":[174],"Data":[175],"were":[176,230,267],"collected":[177],"over":[178],"year":[181],"period":[182],"adjunct":[185],"ongoing":[187],"research":[188],"studies":[189],"ADHD,":[191],"ASD,":[192],"22q11DS.":[194],"task":[198],"previously":[201],"validated":[202],"measure":[203],"interval":[205],"with":[207,270],"target":[208],"4,":[211],"8,":[212],"12,":[213],"16,":[214],"20":[216],"seconds":[217],"repeated":[218,240],"four":[219],"times":[220],"each":[221,234],"random":[223],"order.":[224],"Time":[225],"consistency":[229],"analyzed":[231],"separately":[232],"samples":[238],"using":[239],"measures":[241],"mixed":[242],"effects":[243],"regression.":[244],"Across":[245],"all":[246],"samples,":[247],"younger":[248],"age":[249],"most":[252],"consistent":[253],"predictor":[254],"variability.":[258,272],"High":[259],"levels":[260],"inattention":[262],"ADHD":[265],"group":[266,295],"also":[268],"associated":[269],"increased":[271,282],"Both":[273],"ASD":[275,294],"22q11DS":[277],"groups":[278],"showed":[279],"evidence":[280],"response":[283,327],"typically":[287],"developing":[288],"comparison":[289],"groups;":[290],"effect":[297],"diagnosis":[299],"moderated":[301],"by":[302],"working":[303],"memory.":[304],"results":[306],"implications":[308],"for":[309],"empirical":[310],"investigations":[311],"across":[315],"multiple":[316],"psychopathology":[319],"highlight":[321],"importance":[323],"considering":[325],"both":[326],"developmental":[330],"factors":[331],"(e.g.,":[332],"maturation":[333],"circuits)":[336],"formation":[339],"new":[341],"theories":[342],"linking":[343],"substrates":[345],"emergence":[348],"constellations.":[351]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}