{"id":"https://openalex.org/W83139663","doi":null,"title":"Marcadores moleculares de inflamaci\u00f3n en la depresi\u00f3n post-ictus","display_name":"Marcadores moleculares de inflamaci\u00f3n en la depresi\u00f3n post-ictus","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W83139663","mag":"83139663"},"language":"es","primary_location":{"id":"pmh:oai:documentacion.fundacionmapfre.org:175969","doi":null,"is_oa":false,"landing_page_url":"https://documentacion.fundacionmapfre.org/documentacion/publico/es/consulta/registro.do?id=175969","pdf_url":null,"source":{"id":"https://openalex.org/S4377196666","display_name":"MAPFRE (Fundaci\u00f3n Mapfre)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210124272","host_organization_name":"Fundaci\u00f3n Mapfre","host_organization_lineage":["https://openalex.org/I4210124272"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Art\u00edculos y Cap\u00edtulos"},"volume":null,"type":"other","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109293400","display_name":"Isabel Jim\u00e9nez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Isabel Jim\u00e9nez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059672802","display_name":"Tom\u00e1s Sobrino","orcid":"https://orcid.org/0000-0002-9760-8690","observed_orcids":["https://orcid.org/0000-0002-9760-8690"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tom\u00e1s Sobrino","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9760-8690","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088102298","display_name":"David Brea","orcid":"https://orcid.org/0000-0003-2365-7374","observed_orcids":["https://orcid.org/0000-0003-2365-7374"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Brea","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2365-7374","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033558827","display_name":"Iv\u00e1n Cristobo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iv\u00e1n Cristobo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028197889","display_name":"Manuel Rodr\u00edguez\u2010Y\u00e1\u00f1ez","orcid":"https://orcid.org/0000-0002-5381-8557","observed_orcids":["https://orcid.org/0000-0002-5381-8557"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manuel Rodr\u00edguez\u2010Y\u00e1\u00f1ez","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5381-8557","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112557034","display_name":"Miguel Blanco Gonz\u00e1lez","orcid":"https://orcid.org/0000-0002-0572-0571","observed_orcids":["https://orcid.org/0000-0002-0572-0571"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miguel Blanco","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0572-0571","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065464517","display_name":"Mart\u00edn Pouso","orcid":"https://orcid.org/0009-0004-9242-6574","observed_orcids":["https://orcid.org/0009-0004-9242-6574"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Pouso","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027758830","display_name":"M Sabucedo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Sabucedo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021632980","display_name":"Rogelio Leira","orcid":"https://orcid.org/0000-0001-7233-2053","observed_orcids":["https://orcid.org/0000-0001-7233-2053"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rogelio Leira","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7233-2053","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103963951","display_name":"Jorge Castillo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Castillo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"2","first_page":"113","last_page":"119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.5054000020027161,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.5054000020027161,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10510","display_name":"Stroke Rehabilitation and Recovery","score":0.4083999991416931,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.03180000185966492,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/post-stroke-depression","display_name":"post-stroke depression","score":0.9539999961853027},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.7710000276565552},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8460000157356262},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.8989999890327454},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9610000252723694},{"id":"https://openalex.org/keywords/icam-1","display_name":"ICAM-1","score":0.9399999976158142},{"id":"https://openalex.org/keywords/high-sensitivity-c-reactive-protein","display_name":"high-sensitivity C-reactive protein","score":0.9670000076293945},{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.9580000042915344},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.8460000157356262},{"id":"https://openalex.org/keywords/stroke-severity","display_name":"stroke severity","score":0.6150000095367432},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.4320000112056732}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9629298448562622},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.7674776911735535},{"id":"https://openalex.org/C2780931571","wikidata":"https://www.wikidata.org/wiki/Q568775","display_name":"Modified Rankin Scale","level":4,"score":0.6446861624717712},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.625775158405304},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.587196409702301},{"id":"https://openalex.org/C2991681754","wikidata":"https://www.wikidata.org/wiki/Q2273097","display_name":"Barthel index","level":3,"score":0.5871667861938477},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4265686273574829},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3371758460998535},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.32537925243377686},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3179389238357544},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.19934070110321045},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.06154748797416687},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:documentacion.fundacionmapfre.org:175969","doi":null,"is_oa":false,"landing_page_url":"https://documentacion.fundacionmapfre.org/documentacion/publico/es/consulta/registro.do?id=175969","pdf_url":null,"source":{"id":"https://openalex.org/S4377196666","display_name":"MAPFRE (Fundaci\u00f3n Mapfre)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210124272","host_organization_name":"Fundaci\u00f3n Mapfre","host_organization_lineage":["https://openalex.org/I4210124272"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Art\u00edculos y Cap\u00edtulos"},{"id":"mag:2337236889","doi":null,"is_oa":false,"landing_page_url":"https://sid.usal.es/idocs/F8/ART10787/trauma2_ictus.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:83139663","doi":null,"is_oa":false,"landing_page_url":"https://app.mapfre.com/fundacion/html/revistas/trauma/v19n2/pdf/02_07.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S171331007","display_name":"Trauma","issn_l":"1460-4086","issn":["1460-4086","1477-0350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Trauma","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1981466881","https://openalex.org/W1983706324","https://openalex.org/W1985726784","https://openalex.org/W1992997185","https://openalex.org/W1999871144","https://openalex.org/W2000934122","https://openalex.org/W2010664010","https://openalex.org/W2019995128","https://openalex.org/W2024087252","https://openalex.org/W2057162613","https://openalex.org/W2062342456","https://openalex.org/W2064023438","https://openalex.org/W2068270366","https://openalex.org/W2080504768","https://openalex.org/W2097711148","https://openalex.org/W2138595885","https://openalex.org/W2149544241","https://openalex.org/W2149977971","https://openalex.org/W2158230122","https://openalex.org/W2168950597"],"related_works":["https://openalex.org/W2337236889","https://openalex.org/W2337970529","https://openalex.org/W3130187613","https://openalex.org/W2946402969","https://openalex.org/W2158557110","https://openalex.org/W3174623785","https://openalex.org/W4388551391","https://openalex.org/W4286698130","https://openalex.org/W2461316350","https://openalex.org/W4404932989"],"abstract_inverted_index":{"Introduction:":[0],"Depresion":[1],"is":[2,13],"frequent":[3],"after":[4,175],"stroke,":[5,36],"finding":[6],"an":[7],"association":[8],"with":[9,33,106,134,136,148],"inflammation.":[10],"Our":[11],"aim":[12],"to":[14],"evaluate":[15],"the":[16,169,173],"relationship":[17,167,178],"between":[18,168,181],"inflammation":[19,182],"in":[20,183],"acute":[21,184],"phase":[22,185],"of":[23,40,79,94],"stroke":[24],"and":[25,27,42,50,58,67,74,85,87,100,144,155,172,186],"depression.\nPatients":[26],"methods:":[28],"We":[29,164],"included":[30],"134":[31],"patients":[32,95],"first":[34],"ischemic":[35],"excluding":[37],"previous":[38],"history":[39],"depression,":[41],"aphasia.":[43],"Stroke":[44],"severity":[45],"was":[46,63,131,179],"evaluated":[47,64],"by":[48,53,71],"NIHSS":[49],"functional":[51],"outcome":[52,113],"modified":[54],"Rankin":[55],"Scale":[56],"(mRS)":[57],"Barthel":[59],"Index":[60],"(BI).":[61],"Depression":[62,128],"at":[65,68,91,98,102,108,129,145,157],"discharge":[66,99,130,158],"1":[69,84,125],"month":[70,110,147],"DSM-IV":[72],"criteria":[73],"Yesavage":[75],"Scale,":[76],"Serum":[77],"levels":[78],"inflammatory":[80],"molecules":[81],"(IL-6,":[82],"ICAM":[83],"high-sensitive-CRP)":[86],"BDNF":[88],"were":[89],"determined":[90],"discharge.\nResults:":[92],"40,3%":[93],"showed":[96,111],"depression":[97,107,156,174,188],"48.1%":[101],"one":[103,109,146],"month.":[104],"Patients":[105],"poor":[112],"(BI":[114],"70":[115],"[90,100]":[116],"vs":[117,124],"100":[118],"[95,100];":[119],"p=0,001;":[120],"mRS":[121],"2":[122],"[1,3]":[123],"[0,2];":[126],"p=0,03).":[127],"independently":[132],"associated":[133],"live":[135],"offspring":[137],"(OR:":[138,159],"7,62;":[139],"CI95%":[140,152,161],"[1,35,":[141],"43,09];":[142],"p=0,022),":[143],"female":[149],"sex":[150],"(OR:5,47;":[151],"[1,45,20,67];":[153],"p=0,012)":[154],"9,36;":[160],"[2,46,35,59];":[162],"p=0,002).":[163],"found":[165,180],"no":[166],"molecular":[170],"markers":[171],"stroke.\nConclusion:":[176],"No":[177],"post-troke":[187]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}