{"id":"https://openalex.org/W82933859","doi":null,"title":"Hunger, food intake and weight: the impact of clomipramine on a refeeding anorexia nervosa population.","display_name":"Hunger, food intake and weight: the impact of clomipramine on a refeeding anorexia nervosa population.","publication_year":1980,"publication_date":"1980-01-01","ids":{"openalex":"https://openalex.org/W82933859","mag":"82933859","pmid":"https://pubmed.ncbi.nlm.nih.gov/6994086"},"language":"en","primary_location":{"id":"pmid:6994086","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6994086","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Postgraduate medical journal","raw_type":"Clinical Trial"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013628157","display_name":"John Hubert Lacey","orcid":"https://orcid.org/0000-0001-7302-6496","observed_orcids":["https://orcid.org/0000-0001-7302-6496"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J H Lacey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069762152","display_name":"Alex Harley Crisp","orcid":"https://orcid.org/0000-0003-4683-9576","observed_orcids":["https://orcid.org/0000-0003-4683-9576"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A H Crisp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.8618,"has_fulltext":false,"cited_by_count":114,"citation_normalized_percentile":{"value":0.89654704,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"56 Suppl 1","issue":null,"first_page":"79","last_page":"85"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10263","display_name":"Eating Disorders and Behaviors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clomipramine","display_name":"clomipramine","score":0.9369999766349792},{"id":"https://openalex.org/keywords/anorexia-nervosa","display_name":"anorexia nervosa","score":0.9980000257492065},{"id":"https://openalex.org/keywords/refeeding","display_name":"refeeding","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hunger","display_name":"hunger","score":0.8149999976158142},{"id":"https://openalex.org/keywords/appetite","display_name":"appetite","score":0.9990000128746033},{"id":"https://openalex.org/keywords/food-consumption","display_name":"dietary intake","score":0.8640000224113464},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.8009999990463257},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.8659999966621399},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.621999979019165},{"id":"https://openalex.org/keywords/eating-habits","display_name":"dietary habits","score":0.5009999871253967},{"id":"https://openalex.org/keywords/antidepressants","display_name":"antidepressants","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C2779305415","wikidata":"https://www.wikidata.org/wiki/Q58713","display_name":"Clomipramine","level":2,"score":0.9617289304733276},{"id":"https://openalex.org/C75908981","wikidata":"https://www.wikidata.org/wiki/Q28578","display_name":"Appetite","level":2,"score":0.8750964403152466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7773418426513672},{"id":"https://openalex.org/C2777031586","wikidata":"https://www.wikidata.org/wiki/Q131749","display_name":"Anorexia nervosa","level":3,"score":0.650446891784668},{"id":"https://openalex.org/C2778654693","wikidata":"https://www.wikidata.org/wiki/Q254327","display_name":"Anorexia","level":2,"score":0.6299200057983398},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6056001782417297},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5400588512420654},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5303167700767517},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5002927780151367},{"id":"https://openalex.org/C2780320433","wikidata":"https://www.wikidata.org/wiki/Q3403879","display_name":"Weight gain","level":3,"score":0.4967511296272278},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.4332357347011566},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.39003786444664},{"id":"https://openalex.org/C2776394216","wikidata":"https://www.wikidata.org/wiki/Q373822","display_name":"Eating disorders","level":2,"score":0.35742121934890747},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.31922417879104614},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2758462429046631},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000856","descriptor_name":"Anorexia Nervosa","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000856","descriptor_name":"Anorexia Nervosa","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002149","descriptor_name":"Energy Intake","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002997","descriptor_name":"Clomipramine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002997","descriptor_name":"Clomipramine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006815","descriptor_name":"Hunger","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:6994086","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6994086","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Postgraduate medical journal","raw_type":"Clinical Trial"},{"id":"mag:82933859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6994086","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2118229015","https://openalex.org/W2008627008","https://openalex.org/W2039713178","https://openalex.org/W2092251742","https://openalex.org/W2018020696","https://openalex.org/W1999764193","https://openalex.org/W2047217817","https://openalex.org/W2106220161","https://openalex.org/W2050370794","https://openalex.org/W2073588187"],"abstract_inverted_index":{"This":[0],"double-blind":[1],"controlled":[2],"study":[3],"examines":[4],"the":[5,25,30,45,97,102,105,132,136],"impact":[6],"of":[7,68,104,135],"clomipramine":[8,78],"when":[9],"taken":[10],"by":[11,24],"an":[12],"anorexia":[13],"nervosa":[14],"population,":[15],"refeeding":[16],"in":[17,82,109],"hospital,":[18],"over":[19],"and":[20,55,86,127,156],"above":[21],"that":[22],"generated":[23],"established":[26],"treatment":[27],"programme.":[28],"Of":[29],"16":[31],"patients":[32],"studied,":[33],"all":[34],"reached":[35],"their":[36,83],"target":[37],"weights":[38,140],"including":[39],"three":[40],"who":[41],"asked":[42],"to":[43,61,107,116,123,131,145],"leave":[44],"study.":[46],"Clomipramine":[47],"was":[48,74],"significantly":[49],"associated":[50,63],"with":[51,64],"increased":[52],"hunger,":[53,125,153],"appetite":[54,126],"energy":[56,158],"intake.":[57,159],"It":[58],"tended,":[59],"though,":[60],"be":[62],"a":[65,119],"reduced":[66],"rate":[67],"weight":[69,89,134],"gain,":[70],"possibly":[71],"because":[72],"activity":[73],"increased.":[75],"Patients":[76],"receiving":[77],"were":[79],"more":[80],"stable":[81],"eating":[84],"habits":[85],"maintained":[87],"body":[88,110,133],"better":[90],"than":[91],"those":[92],"on":[93],"placebo":[94],"after":[95],"leaving":[96],"trial.":[98],"These":[99],"findings":[100],"indicate":[101],"sensitivity":[103],"hypothalamus":[106],"changes":[108],"weight.":[111],"Clomipramine,":[112],"which":[113,141],"is":[114],"known":[115],"act":[117],"at":[118],"hypothalamic":[120,147],"level,":[121],"seems":[122],"influence":[124,152],"dietary":[128],"intake":[129],"according":[130],"patient.":[137],"The":[138],"threshold":[139],"have":[142],"been":[143],"shown":[144],"trigger":[146],"sexual":[148],"responses,":[149],"may":[150],"also":[151],"appetite,":[154],"motility":[155],"voluntary":[157]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}