{"id":"https://openalex.org/W827874409","doi":null,"title":"The role of inflammatory cytokines interleukin 6 and tumor necrosis factor-alpha for detection of acute surgical abdomen in emergency room","display_name":"The role of inflammatory cytokines interleukin 6 and tumor necrosis factor-alpha for detection of acute surgical abdomen in emergency room","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W827874409","mag":"827874409"},"language":"en","primary_location":{"id":"pmh:oai:openaccess.marmara.edu.tr:11424/2178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11424/2178","pdf_url":"http://hdl.handle.net/11424/2178","source":{"id":"https://openalex.org/S4306401380","display_name":"Dspace Repository (Marmara \u00dcniversitesi)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74897591","host_organization_name":"Marmara University","host_organization_lineage":["https://openalex.org/I74897591"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11424/2178","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005781054","display_name":"\u00d6zge Onur","orcid":"https://orcid.org/0000-0002-0110-3533","observed_orcids":["https://orcid.org/0000-0002-0110-3533"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d6zge Onur","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0110-3533","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108405354","display_name":"Erol Erden \u00dcnl\u00fcer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erol Erden \u00dcnl\u00fcer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086753639","display_name":"Arzu Denizba\u015f\u0131","orcid":"https://orcid.org/0000-0002-4589-8251","observed_orcids":["https://orcid.org/0000-0002-4589-8251"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arzu Denizba\u015f\u0131","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4589-8251","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5054393565","display_name":"\u00d6zlem G\u00fcneysel","orcid":"https://orcid.org/0000-0002-1833-2199","observed_orcids":["https://orcid.org/0000-0002-1833-2199"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d6zlem G\u00fcneysel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1833-2199","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05423503,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.7416999936103821,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.7416999936103821,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.08669999986886978,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11473","display_name":"Appendicitis Diagnosis and Management","score":0.03830000013113022,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8980000019073486},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9700000286102295},{"id":"https://openalex.org/keywords/acute-abdomen","display_name":"acute abdomen","score":0.8629999756813049},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9419999718666077},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8119999766349792},{"id":"https://openalex.org/keywords/abdominal-pain","display_name":"abdominal pain","score":0.9490000009536743},{"id":"https://openalex.org/keywords/emergency-department","display_name":"emergency department","score":0.7200000286102295},{"id":"https://openalex.org/keywords/choledocholithiasis","display_name":"choledocholithiasis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9137848019599915},{"id":"https://openalex.org/C2779983558","wikidata":"https://www.wikidata.org/wiki/Q9597","display_name":"Abdomen","level":2,"score":0.7430296540260315},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.5529996752738953},{"id":"https://openalex.org/C2778856562","wikidata":"https://www.wikidata.org/wiki/Q424317","display_name":"Acute abdomen","level":2,"score":0.5116096138954163},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4796619713306427},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.4695988893508911},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4427948594093323},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.43087849020957947},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3633243143558502}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:openaccess.marmara.edu.tr:11424/2178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11424/2178","pdf_url":"http://hdl.handle.net/11424/2178","source":{"id":"https://openalex.org/S4306401380","display_name":"Dspace Repository (Marmara \u00dcniversitesi)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74897591","host_organization_name":"Marmara University","host_organization_lineage":["https://openalex.org/I74897591"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"mag:827874409","doi":null,"is_oa":false,"landing_page_url":"http://dspace.marmara.edu.tr/handle/11424/2178","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openaccess.marmara.edu.tr:11424/2178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11424/2178","pdf_url":"http://hdl.handle.net/11424/2178","source":{"id":"https://openalex.org/S4306401380","display_name":"Dspace Repository (Marmara \u00dcniversitesi)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I74897591","host_organization_name":"Marmara University","host_organization_lineage":["https://openalex.org/I74897591"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W827874409.pdf","grobid_xml":"https://content.openalex.org/works/W827874409.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W118488404","https://openalex.org/W1973190276","https://openalex.org/W1981772756","https://openalex.org/W1988386616","https://openalex.org/W2026769337","https://openalex.org/W2035192249","https://openalex.org/W2043516997","https://openalex.org/W2063579231","https://openalex.org/W2114957102","https://openalex.org/W2165889447","https://openalex.org/W2230144546","https://openalex.org/W2404218605","https://openalex.org/W2410264402","https://openalex.org/W2410330794"],"related_works":["https://openalex.org/W7024382155","https://openalex.org/W7164914434","https://openalex.org/W1845196765","https://openalex.org/W2043339798","https://openalex.org/W1507500502","https://openalex.org/W2074920729","https://openalex.org/W1439256453","https://openalex.org/W2412408699","https://openalex.org/W1029807300","https://openalex.org/W1546785940"],"abstract_inverted_index":{"Objectives:":[0],"The":[1,97,146,184],"aim":[2],"of":[3,44,89,100,110,164,200],"this":[4,138],"study":[5,46],"is":[6],"to":[7,49],"determine":[8],"whether":[9],"interleukin":[10],"6":[11],"(IL-":[12],"6)":[13],"and":[14,29,52,64,72,106,124,178,204],"tumor":[15],"necrosis":[16],"factor":[17],"alpha":[18,74,148,162],"(TNF":[19],"alpha)":[20],"may":[21,226],"be":[22,227],"markers":[23],"for":[24,69,230],"acute":[25],"surgical":[26,177,220,231],"abdomen.":[27,232],"\\nMaterials":[28],"Methods:":[30],"Patients":[31],"over":[32],"18":[33],"years":[34,105],"old":[35],"were":[36,83,92,118,150,187,216],"enrolled":[37,93,119],"in":[38,94,120,152,190,218],"the":[39,45,50,77,95,101,107,111,121,125,140,153,160,165,191,198,201,219],"study.":[40,96],"After":[41],"a":[42,228],"description":[43],"was":[47,58,67,103,113,129,144,171,206],"given":[48],"patients":[51,91,117,134,156,194],"their":[53],"families,":[54],"written":[55],"informed":[56],"consent":[57],"obtained.":[59],"During":[60],"routine":[61],"laboratuary":[62],"assays":[63],"treatment,":[65],"blood":[66],"collected":[68],"studying":[70],"IL-6":[71,185,214,225],"TNF":[73,147,161],"levels.":[75],"For":[76],"control":[78,167,202],"group,":[79,139,168,203],"healthy":[80,166],"adults\u2019":[81],"sera":[82],"studied.":[84],"\\n":[85,223],"\\nResults:":[86],"A":[87],"total":[88],"80":[90],"mean":[98,108],"age":[99,109],"males":[102],"43\u00b18":[104],"females":[112],"51\u00b17":[114],"years.":[115],"41":[116],"non-surgical":[122,179],"group":[123],"most":[126,141],"common":[127,142],"reason":[128],"urinary":[130],"tract":[131],"infection.":[132],"39":[133],"had":[135],"surgery.":[136],"In":[137],"pathology":[143],"cholesistolithiasis.":[145],"levels":[149,163,186,199,215],"higher":[151,189,217],"abdominal":[154,180,192,211],"pain":[155,181,193,212],"when":[157,195],"compared":[158,196],"with":[159,197],"but":[169],"there":[170,205],"no":[172],"statistically":[173,207],"significant":[174,208],"difference":[175,209],"between":[176,210],"groups":[182],"(p>0.05).":[183],"also":[188],"groups.":[213],"abdomen":[221],"group.":[222],"\\nConclusion:":[224],"marker":[229]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}