{"id":"https://openalex.org/W82415783","doi":null,"title":"Luteolin inhibits mast cell-mediated allergic inflammation.","display_name":"Luteolin inhibits mast cell-mediated allergic inflammation.","publication_year":2013,"publication_date":"2013-10-01","ids":{"openalex":"https://openalex.org/W82415783","mag":"82415783","pmid":"https://pubmed.ncbi.nlm.nih.gov/24382176"},"language":"en","primary_location":{"id":"pmid:24382176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24382176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biological regulators and homeostatic agents","raw_type":"Editorial"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010719890","display_name":"Spyridon K. Kritas","orcid":"https://orcid.org/0000-0002-3540-9928","observed_orcids":["https://orcid.org/0000-0002-3540-9928"]},"institutions":[{"id":"https://openalex.org/I21370196","display_name":"Aristotle University of Thessaloniki","ror":"https://ror.org/02j61yw88","country_code":"GR","type":"education","lineage":["https://openalex.org/I21370196"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"S K Kritas","raw_affiliation_strings":["Department of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, Macedonia, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, Macedonia, Greece","institution_ids":["https://openalex.org/I21370196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051567934","display_name":"Andrea Saggini","orcid":"https://orcid.org/0000-0001-8814-441X","observed_orcids":["https://orcid.org/0000-0001-8814-441X"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Saggini","raw_affiliation_strings":["Department of Dermatology, University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080902126","display_name":"Giuseppe Varvara","orcid":"https://orcid.org/0000-0002-7501-0794","observed_orcids":["https://orcid.org/0000-0002-7501-0794"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Varvara","raw_affiliation_strings":["Dental School, University of Chieti-Pescara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental School, University of Chieti-Pescara, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009678026","display_name":"Giovanna Murmura","orcid":"https://orcid.org/0000-0003-3054-0203","observed_orcids":["https://orcid.org/0000-0003-3054-0203","https://orcid.org/0009-0005-6252-8913"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Murmura","raw_affiliation_strings":["Dental School, University of Chieti-Pescara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental School, University of Chieti-Pescara, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043479380","display_name":"Alessandro Caraffa","orcid":"https://orcid.org/0000-0002-7733-6413","observed_orcids":["https://orcid.org/0000-0002-7733-6413"]},"institutions":[{"id":"https://openalex.org/I27483092","display_name":"University of Perugia","ror":"https://ror.org/00x27da85","country_code":"IT","type":"education","lineage":["https://openalex.org/I27483092"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Caraffa","raw_affiliation_strings":["Orthopedic Division, University of Perugia, Perugia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Division, University of Perugia, Perugia, Italy","institution_ids":["https://openalex.org/I27483092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063376067","display_name":"Pierluigi Antinolfi","orcid":"https://orcid.org/0000-0002-9049-3683","observed_orcids":["https://orcid.org/0000-0002-9049-3683"]},"institutions":[{"id":"https://openalex.org/I27483092","display_name":"University of Perugia","ror":"https://ror.org/00x27da85","country_code":"IT","type":"education","lineage":["https://openalex.org/I27483092"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P Antinolfi","raw_affiliation_strings":["Orthopedic Division, University of Perugia, Perugia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Division, University of Perugia, Perugia, Italy","institution_ids":["https://openalex.org/I27483092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068152459","display_name":"Elena Toniato","orcid":"https://orcid.org/0000-0002-2389-5375","observed_orcids":["https://orcid.org/0000-0002-2389-5375"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E Toniato","raw_affiliation_strings":["Immunology Division, Medical School, University of Chieti-Pescara, Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Division, Medical School, University of Chieti-Pescara, Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074670642","display_name":"Andrea Pantalone","orcid":"https://orcid.org/0000-0003-2356-811X","observed_orcids":["https://orcid.org/0000-0003-2356-811X"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Pantalone","raw_affiliation_strings":["Orthopedic Division, University of Chieti-Pescara, Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedic Division, University of Chieti-Pescara, Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084120005","display_name":"Giampiero Neri","orcid":"https://orcid.org/0000-0002-4078-3973","observed_orcids":["https://orcid.org/0000-0002-4078-3973"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Neri","raw_affiliation_strings":["Department of Neurosciences and Imaging, Faculty of Medicine and Surgery, G. d'\u0092Annunzio University Chieti-Pescara, Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences and Imaging, Faculty of Medicine and Surgery, G. d'\u0092Annunzio University Chieti-Pescara, Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084999451","display_name":"Stavros Frydas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21370196","display_name":"Aristotle University of Thessaloniki","ror":"https://ror.org/02j61yw88","country_code":"GR","type":"education","lineage":["https://openalex.org/I21370196"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"S Frydas","raw_affiliation_strings":["Department of Parasitology, School of Veterinary Medicine, University of Thessaloniki, Macedonia, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, School of Veterinary Medicine, University of Thessaloniki, Macedonia, Greece","institution_ids":["https://openalex.org/I21370196"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M Rosati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210147037","display_name":"Azienda USL di Pescara","ror":"https://ror.org/048ym4d69","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210147037"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Rosati","raw_affiliation_strings":["Gynecology Clinic, Pescara Hospital, Pescara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gynecology Clinic, Pescara Hospital, Pescara, Italy","institution_ids":["https://openalex.org/I4210147037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065655146","display_name":"Matteo Maria Tei","orcid":"https://orcid.org/0000-0002-3254-2205","observed_orcids":["https://orcid.org/0000-0002-3254-2205"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Tei","raw_affiliation_strings":["Nicola\u0092s Foundation, Onlus, Arezzo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nicola\u0092s Foundation, Onlus, Arezzo, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085191929","display_name":"Andrea Speziali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Speziali","raw_affiliation_strings":["Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059987642","display_name":"Raoul Saggini","orcid":"https://orcid.org/0000-0002-6379-4472","observed_orcids":["https://orcid.org/0000-0002-6379-4472","https://orcid.org/0000-0002-2729-0461"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R Saggini","raw_affiliation_strings":["Department of Neurosciences and Imaging, Faculty of Medicine and Surgery, G. d'\u0092Annunzio University Chieti-Pescara, Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences and Imaging, Faculty of Medicine and Surgery, G. d'\u0092Annunzio University Chieti-Pescara, Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":null,"display_name":"F Pandolfi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F Pandolfi","raw_affiliation_strings":["Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy","institution_ids":["https://openalex.org/I103320735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028878214","display_name":"Giuliano Giorgio Cerulli","orcid":"https://orcid.org/0000-0003-4990-1902","observed_orcids":["https://orcid.org/0000-0003-4990-1902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Cerulli","raw_affiliation_strings":["Nicola\u0092s Foundation, Onlus, Arezzo, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nicola\u0092s Foundation, Onlus, Arezzo, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085356549","display_name":"Theoharis Constantin Theoharides","orcid":"https://orcid.org/0000-0002-1598-460X","observed_orcids":["https://orcid.org/0000-0002-1598-460X"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T C Theoharides","raw_affiliation_strings":["Department of Pharmacology and Experimental Therapeutics, Biochemistry and Internal Medicine Tufts University School of Medicine, Tufts-New England Medi-cal Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Experimental Therapeutics, Biochemistry and Internal Medicine Tufts University School of Medicine, Tufts-New England Medi-cal Center, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054106836","display_name":"Pio Conti","orcid":"https://orcid.org/0000-0002-9475-4924","observed_orcids":["https://orcid.org/0000-0002-9475-4924"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P Conti","raw_affiliation_strings":["Immunology Division, Medical School, University of Chieti-Pescara, Chieti, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunology Division, Medical School, University of Chieti-Pescara, Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":65,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"4","first_page":"955","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9258000254631042,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9258000254631042,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.0731000006198883,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/luteolin","display_name":"luteolin","score":1.0},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8429999947547913},{"id":"https://openalex.org/keywords/allergic-inflammation","display_name":"allergic inflammation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/mast-cell-activation","display_name":"mast cell activation","score":0.8610000014305115},{"id":"https://openalex.org/keywords/fcepsilonri","display_name":"Fc\u03b5RI","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ige","display_name":"IgE","score":0.7329999804496765},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9449999928474426},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.781000018119812},{"id":"https://openalex.org/keywords/mediator-release","display_name":"mediator release","score":0.5659999847412109},{"id":"https://openalex.org/keywords/allergy","display_name":"allergy","score":0.36800000071525574}],"concepts":[{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.7236727476119995},{"id":"https://openalex.org/C2776080593","wikidata":"https://www.wikidata.org/wiki/Q415011","display_name":"Luteolin","level":4,"score":0.702423632144928},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.6900614500045776},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6324568390846252},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.575854480266571},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5752030611038208},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.5685617923736572},{"id":"https://openalex.org/C2779675166","wikidata":"https://www.wikidata.org/wiki/Q4732119","display_name":"Allergic inflammation","level":3,"score":0.5318453311920166},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4701545238494873},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46680691838264465},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.4299180507659912},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3822297155857086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38086554408073425},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.12100639939308167},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11478570103645325},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.06810539960861206},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018926","descriptor_name":"Anti-Allergic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D047311","descriptor_name":"Luteolin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:24382176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24382176","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biological regulators and homeostatic agents","raw_type":"Editorial"},{"id":"mag:3023144219","doi":null,"is_oa":false,"landing_page_url":"https://ikee.lib.auth.gr/record/280035","pdf_url":null,"source":{"id":"https://openalex.org/S199192407","display_name":"International Journal of Immunopathology and Pharmacology","issn_l":"0394-6320","issn":["0394-6320","2058-7384"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Immunopathology and Pharmacology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4220926815","https://openalex.org/W2005072324","https://openalex.org/W4394564462","https://openalex.org/W2127172511","https://openalex.org/W1925689439","https://openalex.org/W2137347703","https://openalex.org/W2910133655","https://openalex.org/W2040511489","https://openalex.org/W2753204520","https://openalex.org/W2417165021"],"abstract_inverted_index":{"Mast":[0],"cells":[1,31,71],"are":[2,12],"ubiquitous":[3],"in":[4,18,36,40,48],"the":[5,58,67,135],"body":[6],"and":[7,47,99,120,130],"multifunctional":[8],"immune":[9,42],"cells;":[10],"they":[11],"known":[13],"to":[14,24,44,51,91,103],"be":[15],"primary":[16],"responders":[17],"allergic":[19],"reactions,":[20],"orchestrating":[21],"strong":[22],"responses":[23,43],"minute":[25],"amounts":[26],"of":[27,60,69,75,87,107,137],"allergens.":[28],"Mature":[29],"mast":[30,70,126,140],"perform":[32],"important":[33],"beneficial":[34],"roles":[35],"host":[37],"defense,":[38],"both":[39],"IgE-dependent":[41],"certain":[45],"parasites":[46],"natural":[49],"immunity":[50],"bacterial":[52],"infection.":[53],"In":[54],"IgE-associated":[55],"biological":[56],"responses,":[57],"crosslinking":[59],"Fc\u03b5RI-bound":[61],"IgE":[62,80],"with":[63],"multivalent":[64,82],"antigens":[65],"initiate":[66],"activation":[68],"by":[72,81],"promoting":[73],"aggregation":[74],"FceRI.":[76],"This":[77],"cross-linking":[78],"receptor-bound":[79],"Ag":[83],"initiates":[84],"a":[85,104,122],"cascade":[86],"intracellular":[88],"reactions":[89],"leading":[90],"mediator":[92],"release":[93],"such":[94],"as":[95],"proinflammatory":[96],"mediators,":[97],"chemokines":[98],"cytokines.":[100],"Luteolin":[101],"belongs":[102],"flavone":[105],"group":[106],"compounds":[108],"called":[109],"flavonoids,":[110],"it":[111],"has":[112],"anti-oxidant":[113],"properties,":[114],"inhibits":[115],"some":[116],"cancer":[117],"cell":[118,141],"proliferation":[119],"exerts":[121],"regulatory":[123],"effect":[124],"on":[125,139],"cell-mediated":[127],"inflammatory":[128],"diseases":[129],"allergy.":[131],"Here":[132],"we":[133],"report":[134],"impact":[136],"luteolin":[138],"activation.":[142]},"counts_by_year":[{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}