{"id":"https://openalex.org/W819210546","doi":null,"title":"A plant resistance mechanism that promotes the emergence of resistance-breaking variants of potato Y potyvirus","display_name":"A plant resistance mechanism that promotes the emergence of resistance-breaking variants of potato Y potyvirus","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W819210546","mag":"819210546"},"language":"en","primary_location":{"id":"pmh:oai:repository.arizona.edu:10150/288987","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/288987","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation-Reproduction (electronic)"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083478775","display_name":"Rodolfo Acosta-Leal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rodolfo Acosta-Leal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5083478775"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10135","display_name":"Insect-Plant Interactions and Control","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plant-resistance","display_name":"plant resistance","score":0.3009999990463257},{"id":"https://openalex.org/keywords/virus-accumulation","display_name":"virus accumulation","score":0.47099998593330383},{"id":"https://openalex.org/keywords/cell-to-cell-movement","display_name":"cell-to-cell movement","score":0.8460000157356262},{"id":"https://openalex.org/keywords/systemic-infection","display_name":"systemic infection","score":0.6779999732971191},{"id":"https://openalex.org/keywords/quasispecies","display_name":"quasispecies","score":0.5920000076293945},{"id":"https://openalex.org/keywords/viral-fitness","display_name":"viral fitness","score":0.5379999876022339},{"id":"https://openalex.org/keywords/nicotiana-tabacum","display_name":"tobacco","score":0.3230000138282776}],"concepts":[{"id":"https://openalex.org/C2776625791","wikidata":"https://www.wikidata.org/wiki/Q3400142","display_name":"Potyvirus","level":4,"score":0.9392277002334595},{"id":"https://openalex.org/C2780504191","wikidata":"https://www.wikidata.org/wiki/Q29007110","display_name":"Potato virus Y","level":4,"score":0.8358032703399658},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7841438055038452},{"id":"https://openalex.org/C180032290","wikidata":"https://www.wikidata.org/wiki/Q1664296","display_name":"Inoculation","level":2,"score":0.7679905891418457},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6588833928108215},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6387461423873901},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5876299738883972},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.5291686058044434},{"id":"https://openalex.org/C109110057","wikidata":"https://www.wikidata.org/wiki/Q1495434","display_name":"Plant virus","level":3,"score":0.4013475179672241},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37510740756988525},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32182377576828003},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.2438829243183136},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.arizona.edu:10150/288987","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/288987","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation-Reproduction (electronic)"},{"id":"mag:819210546","doi":null,"is_oa":false,"landing_page_url":"http://arizona.openrepository.com/arizona/handle/10150/288987","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.6875,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2035628855","https://openalex.org/W2008415109","https://openalex.org/W1996117936","https://openalex.org/W2058788631","https://openalex.org/W2778707671","https://openalex.org/W1536755026","https://openalex.org/W3199944305","https://openalex.org/W2774018063","https://openalex.org/W2807607784","https://openalex.org/W2328205871"],"abstract_inverted_index":{"Tobacco":[0],"Virgin":[1],"A":[2],"Mutant":[3],"(VAM)":[4],"exhibits":[5],"apparent":[6],"immunity":[7],"to":[8,81,92,106,209,284,292,302,332],"several":[9,37],"potyviruses":[10],"in":[11,59,66,143,178,194,243,270,286,306],"a":[12,118,266,281,294,303,328,333],"strain-specific":[13],"manner.":[14,247],"Its":[15],"resistance":[16,169,325,331],"was":[17,45,91,151,157,215,236,252],"generated":[18],"by":[19,26,226,255],"UV":[20],"irradiation,":[21],"and":[22,71,86,105,222,241],"is":[23,314],"partially":[24],"conditioned":[25],"the":[27,48,72,94,108,112,136,147,180,187,195,205,211,256,261,273,307,315,319],"recessive":[28],"gene":[29],"va.":[30],"This":[31,248,313],"allele":[32,245],"has":[33],"been":[34],"introgressed":[35],"into":[36],"breeding":[38],"fines":[39],"such":[40],"as":[41,135],"NC745.":[42],"Previously,":[43],"it":[44],"observed":[46],"that":[47,97],"inoculation":[49],"of":[50,54,101,111,121,186,204,268,276,297,322],"an":[51,79,223,244],"avirulent":[52,228],"strain":[53],"potato":[55],"Y":[56],"potyvirus":[57],"(PVY(NN))":[58],"both":[60,84,144],"resistant":[61,103,145],"genotypes,":[62],"caused":[63],"systemic":[64,274,335],"infection":[65],"some":[67],"NC745":[68,85,125],"plants":[69,77],"only,":[70],"virus":[73,129,148,234,263,299,308],"recovered":[74,158],"from":[75,160,163,239,280],"these":[76,102],"acquired":[78],"ability":[80],"easily":[82,253],"infect":[83],"VAM.":[87],"The":[88,202,230],"current":[89],"study":[90],"identify":[93],"host":[95],"factors":[96],"define":[98],"each":[99],"one":[100],"phenotypes,":[104],"characterize":[107],"pathogenic":[109],"properties":[110],"evolving":[113],"virus.":[114],"VAM":[115,200,213,231],"cells":[116],"supported":[117],"reduced":[119],"rate":[120,221,296],"PVY(NN)-accumulation":[122],"compared":[123],"with":[124,217],"cells,":[126],"which":[127],"accumulated":[128],"progeny":[130],"at,":[131],"he":[132],"same":[133,196],"level":[134],"susceptible":[137],"control":[138],"Burley":[139],"21":[140],"(B21).":[141],"However,":[142],"tobaccos":[146],"cell-to-cell":[149],"movement":[150],"similarly":[152],"impaired.":[153],"Even":[154],"so,":[155],"PVY(NN)":[156],"sooner":[159],"NC745-":[161],"than":[162],"VAM-inoculated":[164],"leaves.":[165],"After":[166],"PVY(NN)-detection,":[167],"emerging":[168,206],"breaking":[170],"(RB)":[171],"variants":[172,182,208],"were":[173,192],"also":[174],"recovered.":[175],"Surprisingly,":[176],"just":[177],"VAM,":[179],"RB":[181,207,258,277],"never":[183],"moved":[184],"out":[185],"inoculated":[188],"leaves,":[189],"until":[190],"they":[191],"reinoculated":[193],"or":[197],"another":[198],"uninoculated":[199],"plant.":[201],"inability":[203],"exit":[210],"PVY(NN)-inoculated":[212],"leaves":[214],"associated":[216],"their":[218],"low":[219],"accumulation":[220,235,300],"obstruction":[224],"imposed":[225],"coinfecting":[227],"genotypes.":[229],"factor":[232],"restricting":[233],"inherited":[237],"independently":[238],"va":[240],"operated":[242],"doses":[246],"gene,":[249],"named":[250],"rvam2,":[251],"overcome":[254],"isolated":[257],"variants,":[259,278],"but":[260],"underlying":[262],"modification(s)":[264],"implied":[265],"loss":[267],"fitness":[269],"B21.":[271],"Thus,":[272],"emergence":[275],"starting":[279],"quasispecies,":[282],"adapted":[283],"accumulate":[285],"Rvam2":[287],"genotypes":[288],"(e.g.,":[289],"B21),":[290],"seems":[291],"require":[293],"high":[295],"local":[298],"linked":[301],"selective":[304],"constraint":[305],"intercellular":[309],"and/or":[310],"intertissular":[311],"traffic.":[312],"first":[316],"report":[317],"where":[318],"combined":[320],"action":[321],"two":[323],"vulnerable":[324],"mechanisms":[326],"confers":[327],"stronger":[329],"plant":[330],"viral":[334],"infection.":[336]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}