{"id":"https://openalex.org/W81609256","doi":"https://doi.org/10.1016/s0889-857x(05)70204-0","title":"PATHOGENESIS OF RHEUMATOID ARTHRITIS","display_name":"PATHOGENESIS OF RHEUMATOID ARTHRITIS","publication_year":2001,"publication_date":"2001-05-01","ids":{"openalex":"https://openalex.org/W81609256","doi":"https://doi.org/10.1016/s0889-857x(05)70204-0","mag":"81609256","pmid":"https://pubmed.ncbi.nlm.nih.gov/11396095"},"language":"en","primary_location":{"id":"doi:10.1016/s0889-857x(05)70204-0","doi":"https://doi.org/10.1016/s0889-857x(05)70204-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0889-857x(05)70204-0","pdf_url":null,"source":{"id":"https://openalex.org/S28431432","display_name":"Rheumatic Disease Clinics of North America","issn_l":"0889-857X","issn":["0889-857X","1558-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic Disease Clinics of North America","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111488027","display_name":"Gabriel S. Panayi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriel S. Panayi","raw_affiliation_strings":["Department of Rheumatology, Guy's, King's and St Thomas' Medical School, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Guy's, King's and St Thomas' Medical School, London, United Kingdom","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091738058","display_name":"Valerie Corrigall","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Valerie M. Corrigall","raw_affiliation_strings":["Rheumatology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057803401","display_name":"Costantino Pitzalis","orcid":"https://orcid.org/0000-0003-1326-5051","observed_orcids":["https://orcid.org/0000-0003-1326-5051"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Costantino Pitzalis","raw_affiliation_strings":["King \u2018s College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King \u2018s College London","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":2.4521,"has_fulltext":false,"cited_by_count":184,"citation_normalized_percentile":{"value":0.93023256,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"27","issue":"2","first_page":"317","last_page":"334"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.8270000219345093},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.8320000171661377},{"id":"https://openalex.org/keywords/cd4-monoclonal-antibody","display_name":"CD4 monoclonal antibody","score":0.8450000286102295},{"id":"https://openalex.org/keywords/synovial-t-cells","display_name":"synovial T cells","score":0.781000018119812},{"id":"https://openalex.org/keywords/joint-damage","display_name":"joint destruction","score":0.7300000190734863},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.8840000033378601},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9150000214576721},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/synovitis","display_name":"synovitis","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7883975505828857},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.7217816710472107},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.6866883635520935},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6395032405853271},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.6058833003044128},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5626691579818726},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5229185819625854},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.45920851826667786},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4537610411643982},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.31689196825027466},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15831217169761658}],"mesh":[{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0889-857x(05)70204-0","doi":"https://doi.org/10.1016/s0889-857x(05)70204-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0889-857x(05)70204-0","pdf_url":null,"source":{"id":"https://openalex.org/S28431432","display_name":"Rheumatic Disease Clinics of North America","issn_l":"0889-857X","issn":["0889-857X","1558-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic Disease Clinics of North America","raw_type":"journal-article"},{"id":"pmid:11396095","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11396095","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatic diseases clinics of North America","raw_type":"Journal Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/1ccc7c7e-b5a3-4e14-a20d-26f14a14c3bc","doi":null,"is_oa":false,"landing_page_url":"http://www.scopus.com/inward/record.url?scp=0035010959&partnerID=8YFLogxK","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Panayi, G S, Corrigall, V M & Pitzalis, C 2001, 'Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts', Rheumatic Diseases Clinics of North America, vol. 27, no. 2, pp. 317 - 334. https://doi.org/10.1016/S0889-857X(05)70204-0","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":137,"referenced_works":["https://openalex.org/W75593237","https://openalex.org/W76382802","https://openalex.org/W122949193","https://openalex.org/W230393467","https://openalex.org/W269067557","https://openalex.org/W278851545","https://openalex.org/W1480778114","https://openalex.org/W1484000129","https://openalex.org/W1485492992","https://openalex.org/W1518307677","https://openalex.org/W1534645474","https://openalex.org/W1561950821","https://openalex.org/W1568317937","https://openalex.org/W1578883193","https://openalex.org/W1582144994","https://openalex.org/W1584068751","https://openalex.org/W1601356132","https://openalex.org/W1629559958","https://openalex.org/W1648671938","https://openalex.org/W1677043489","https://openalex.org/W1679707032","https://openalex.org/W1814172467","https://openalex.org/W1820973630","https://openalex.org/W1874771490","https://openalex.org/W1901808362","https://openalex.org/W1912833239","https://openalex.org/W1933742170","https://openalex.org/W1967857969","https://openalex.org/W1968376159","https://openalex.org/W1969596391","https://openalex.org/W1970404248","https://openalex.org/W1972195950","https://openalex.org/W1982092413","https://openalex.org/W1982981322","https://openalex.org/W1983541797","https://openalex.org/W1985238647","https://openalex.org/W1985680749","https://openalex.org/W1987568997","https://openalex.org/W1989997867","https://openalex.org/W1990251286","https://openalex.org/W1993481401","https://openalex.org/W1995557967","https://openalex.org/W1998256351","https://openalex.org/W1999626234","https://openalex.org/W1999683126","https://openalex.org/W2000363224","https://openalex.org/W2001118450","https://openalex.org/W2002991417","https://openalex.org/W2003284223","https://openalex.org/W2004109561","https://openalex.org/W2005139135","https://openalex.org/W2007137447","https://openalex.org/W2007264686","https://openalex.org/W2007384961","https://openalex.org/W2008924465","https://openalex.org/W2011700185","https://openalex.org/W2012827463","https://openalex.org/W2016099749","https://openalex.org/W2016446407","https://openalex.org/W2018039455","https://openalex.org/W2018527410","https://openalex.org/W2019642817","https://openalex.org/W2021969578","https://openalex.org/W2024863213","https://openalex.org/W2042626190","https://openalex.org/W2043103025","https://openalex.org/W2050591560","https://openalex.org/W2050633514","https://openalex.org/W2052083000","https://openalex.org/W2052316327","https://openalex.org/W2054686030","https://openalex.org/W2057325749","https://openalex.org/W2059427290","https://openalex.org/W2062945620","https://openalex.org/W2064751736","https://openalex.org/W2066290397","https://openalex.org/W2069508774","https://openalex.org/W2072737535","https://openalex.org/W2073917674","https://openalex.org/W2075309835","https://openalex.org/W2075718545","https://openalex.org/W2076342409","https://openalex.org/W2078940753","https://openalex.org/W2079122567","https://openalex.org/W2082479577","https://openalex.org/W2082866606","https://openalex.org/W2085266169","https://openalex.org/W2085534168","https://openalex.org/W2087167272","https://openalex.org/W2088449977","https://openalex.org/W2089456249","https://openalex.org/W2092602103","https://openalex.org/W2098015378","https://openalex.org/W2098252815","https://openalex.org/W2098667156","https://openalex.org/W2099675490","https://openalex.org/W2099853009","https://openalex.org/W2101035519","https://openalex.org/W2104843745","https://openalex.org/W2105487639","https://openalex.org/W2107184059","https://openalex.org/W2110555227","https://openalex.org/W2112066013","https://openalex.org/W2113234718","https://openalex.org/W2120535451","https://openalex.org/W2125501107","https://openalex.org/W2140611998","https://openalex.org/W2141681336","https://openalex.org/W2144152742","https://openalex.org/W2146045246","https://openalex.org/W2156835571","https://openalex.org/W2157542668","https://openalex.org/W2160578379","https://openalex.org/W2161854417","https://openalex.org/W2164851074","https://openalex.org/W2166203843","https://openalex.org/W2169318446","https://openalex.org/W2170842773","https://openalex.org/W2171832676","https://openalex.org/W2279136988","https://openalex.org/W2397308758","https://openalex.org/W2403253550","https://openalex.org/W2406594603","https://openalex.org/W2414997664","https://openalex.org/W2417828165","https://openalex.org/W2460992717","https://openalex.org/W2462132580","https://openalex.org/W2471978186","https://openalex.org/W2992765387","https://openalex.org/W4285719527","https://openalex.org/W4299868448","https://openalex.org/W4313347845","https://openalex.org/W6605033570","https://openalex.org/W6713388313","https://openalex.org/W6716237954","https://openalex.org/W6718935540","https://openalex.org/W7073709917"],"related_works":["https://openalex.org/W2034402043","https://openalex.org/W2385399729","https://openalex.org/W2331456111","https://openalex.org/W2964489454","https://openalex.org/W3055969531","https://openalex.org/W2320688631","https://openalex.org/W4236434195","https://openalex.org/W4232827113","https://openalex.org/W4362732928","https://openalex.org/W2137717947"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
